McMaster University

McMaster University

Roma Semhi

Associate Professor

Location: 3U32

Phone: 905 525-9140 ext 22963



  • BSc(Hons) Pharamcology University College, UK
  • PhD, Imperial College, UK
  • Post-doctoral fellowship, Cambridge University, UK
  • Post-doctoral fellowship Master University

Research interests

  • Hemopoietic mechanisms in eosinophilic asthma — role bone marrow derived progenitor cells in the development of airway eosinophilia
  • Traffic and lung-homing of hemopoietic progenitors to the lungs
  • Role of progenitor cells in tissue remodeling in chronic airway diseases — vascularization and angiogenesis.
  • Role of innate immune pathways in the development and maintenance of persistent eosinophilia in steroid refractory asthma.


  • Ruchong Chen, MD
  • Adrian Bjaates, PhD
  • Steven Smith, PhD
  • Adriana Catalli, PhD
  • Nirooya Sivapalan, MSC
  • Tracey Doyle, MSc
  • Navneet Punia, MSc
  • Jennifer Thompson, MSc
  • Adrian Fanat, MSc

Selected Publications

  1. Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia. Smith SG, Chen R, Kjarsgaard M, Huang C, Oliveria JP, O'Byrne PM, Gauvreau GM, Boulet LP, Lemiere C, Martin J, Nair P, Sehmi R. J Allergy Clin Immunol. 2016 Jan;137(1):75-86
  2. Role of Local Eosinophilopoietic Processes in the Development of Airway Eosinophilia in Prednisone-dependent Severe Asthma. Sehmi R, Smith SG, Kjarsgaard M, Radford K, Boulet LP, Lemiere C, Prazma CM, Ortega H, Martin JG, Nair P. Clin Exp Allergy. 2015 Dec 18.
  3. Thymic stromal lymphopoietin and IL-33 modulate migration of hematopoietic progenitor cells in patients with allergic asthma. Smith SG, Gugilla A, Mukherjee M, Merim K, Irshad A, Tang W, Kinoshita T, Watson B, Oliveria JP, Comeau M, O'Byrne PM, Gauvreau GM, Sehmi R. J Allergy Clin Immunol. 2015 Jun;135(6):1594-602
  4. Thymic stromal lymphopoietin activation of basophils in patients with allergic asthma is IL-3 dependent. Salter BM, Oliveria JP, Nusca G, Smith SG, Watson RM, Comeau M, Sehmi R, Gauvreau GM. J Allergy Clin Immunol. 2015 Dec;136(6):1636-44
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