McMaster University

Population Genomics
Program

Scope of Search

HRM 728 — Genetic Epidemiology & Statistics

  • Fall 2015 Schedule
  • Fall 2014 Schedule
  • Online Resources
  • References

Fall 2015 Schedule

Date Session Instructor Title Reference Material
9/11/2015 1 Sonia Anand Key concepts in genetic epidemiology

Readings - Anand

Lecture Slides - Anand

9/18/2015 2 Russell de Souza Gene diet Interactions

Lecture Slides - de Souza

9/25/2015 3 Joseph Beyene Statistical Issues in genetic studies Part 1

Readings - Beyene

10/2/2015 4 David Meyre Functional genomics -review of gene expression and molecular biology techinques and interpretation

Readings - Meyre

Lecture Slides - Meyre

10/09/2015 5 Kevin Zbuk Pharmacogenetics

Readings - Zbuk

Lecture Slides - Zbuk

10/16/2015 6 Mark Loeb Genetic association studies and GWAS

Readings 1 - Loeb

Readings 2 - Loeb

Readings 3 - Loeb

Lecture Slides - Loeb

10/16/2015     Mid-Term Assignment Due in Class  
10/23/2015 7 Joseph Beyene Statistical issues in genetic studies Part 2  
10/30/2015 8 Guillaume Pare Epigenetics and the potential influence of epigenetic variation on the occurance of phenotypic characterization and disease causation Readings - Pare
11/06/2015 9 David Meyre Analytical challenges in genetic association

Readings - Meyre

Lecture Slides - Meyre Nov

11/13/2015 10 Guillaume Pare Betwixt and between; common and rare variants in human disease
11/20/2015 11 Binod Neupane

Issues in Genetic data analysis and use of PLINK

(Students are not expected to understand all the mathematical details in the paper. A quick scan of what PLINK can do and how it can be used in a student's course project is enough)

Readings 1 - Neupane

Readings 2 - Neupane

Readings 3 - Neupane

11/27/2015 12 Zena Samaan The application of genetic studies in specific disorders: psychiatric genetics

Readings 1 - Samaan

Readings 2 - Samaan

Lecture Slides - Samaan

12/4/2015 13 Binod Neupane / Russell de Souza Wrap up Session - First hour Final exam 2 hour wrap up questions  
12/11/2015 14 Sonia Anand Final Assigment - Independent Study  

Fall 2014 Schedule

Date Session Instructor Title Reference Material
9/12/2015 1 Sonia Anand Key concepts in genetic epidemiology HRM 728 Slides
9/19/2014 2 Guillaume Pare Epigenetics and the potential influence of epigenetic variation on the occurance of phenotypic characterization and disease causation Lecture Slides
9/26/2014 3 Russell de Souza Gene diet Interactions

Ottman

09-22-2014_HRM 728 readings list

Lecture Slides

10/3/2014 4 Joseph Beyene Statistical Issues in genetic studies Part 1 Hattersley AT McCarthy MI
10/10/2014 5 Mark Loeb Gene association studies and GWAS

Epidemiological methods for studying...

J Infect Dis.-2011-Loeb-1031-7

10/17/2014 6 Guillaume Pare Betwixt and between; common and rare variants in human disease

Genetic Heterogeneity in Human Disease

Schizophr Bull-2007-Schork-95-104

Genome-wide association studies

Lecture Slides

10/17/2014     Mid-Term Assignment Due in Class  
10/24/2014 7 David Meyre Functional genomics -review of gene expression and molecular biology techinques and interpretation

Ichimura et al Nature 2012

Lecture Slides

10/31/2014 8 Binod Neupane Issues in Genetic data analysis and use of PLINK

Shaking the tree mapping complex disease genes with

Analysis GWAS data through PLINK

11/7/2014 9 David Meyre Analytical challenges in genetic association

Int J Obes 2013

Lecture Slides

11/14/2014 10 Joseph Beyene Statistical issues in genetic studies Part 2 Lecture Slides
11/21/2014 11 Kevin Zbuk Pharmacogenetics

Effects of CYP2C19 Genotype on Outcomes

Lecture Slides

11/28/2014 12 Zena Samaan The application of genetic studies in specific disorders: psychiatric genetics Lecture Slides
12/5/2014 13 Binod Neupane / Russell de Souza Wrap up Session - First hour Final exam 2 hour wrap up questions  
12/12/2014 14 Sonia Anand Final Assigment - Independent Study  

Online Resources

References