McMaster University

McMaster University

Joseph Macri

, PhD

Associate Professor
Pathology and Molecular Medicine

Division: Clinical Pathology

Clinical Biochemist

Hamilton General Hospital
Hamilton, Ontario
905-527-4322 ext. 46046

3H03 Lecture 1 & 2 Notes (.pdf) (.ppt)
3H03 Lecture 3 Notes (.pdf) (.ppt)

No photo available

Faculty Biography

Education and Professional Standing

  • PhD Biochemistry, University of Windsor, 1997
  • BSc Biochemistry, University of Windsor, 1992
  • BA Psychology, University of Windsor, 1988


  • Investigating the mechanisms involved with regulating the assembly and secretion of hepatic lipoproteins.
  • Utilizing proteomics-based technologies to investigate specific cellular and intracellular mechanism associated with the development of atherosclerosis.

Selected Publications

  • Macri J, Rapundalo ST. Application of proteomics to the study of cardiovascular biology. Trends Cardiovasc Med. 2001 Feb;11(2):66-75. Review.
  • Macri J, Kazemian P, Kulinski A, Rudy D, Aiton A, Thibert RJ, Adeli K. Translocational status of ApoB in the presence of an inhibitor of microsomal triglyceride transfer protein. Biochem Biophys Res Commun. 2000 Oct 5;276(3):1035-47.
  • Macri J, McGee B, Thomas JN, Du P, Stevenson TI, Kilby GW, Rapundalo ST. Cardiac sarcoplasmic reticulum and sarcolemmal proteins separated by two-dimensional electrophoresis: surfactant effects on membrane solubilization. Electrophoresis. 2000 May;21(9):1685-93.
  • Cavallo D, Rudy D, Mohammadi A, Macri J, Adeli K. Studies on degradative mechanisms mediating post-translational fragmentation of apolipoprotein B and the generation of the 70-kDa fragment. J Biol Chem. 1999 Aug 13;274(33):23135-43.
  • Mohammadi A, Macri J, Newton R, Romain T, Dulay D, Adeli K. Effects of atorvastatin on the intracellular stability and secretion of apolipoprotein B in HepG2 cells. Arterioscler Thromb Vasc Biol. 1998 May;18(5):783-93.
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