McMaster University

McMaster University

Christine Lee


Professor, Part-Time
Pathology and Molecular Medicine

Division: Clinical Pathology
Specialty: Infectious diseases and Medical Microbiology

St. Joseph's Healthcare
L424 St. Luke Wing
50 Charlton Avenue East
Hamilton, Ontario

Victoria BC office:
Royal Jubilee Hospital, Microbiology Lab
1952 Bay Street, Victoria BC V8R 1J8

Dr Lee

Faculty Biography

Education and Professional Standing

FRCPC Microbiology, 2000
Royal College Infectious Diseases Certification 2000
FRCPC Internal Medicine, 1998
MD, University of Toronto 1994
University of Toronto:  Internal Medicine , Infectious Diseases and Medical Microbiology Residency


Research Focus

Dr. Lee's research interests include optimal laboratory methods to diagnose and treat Clostridium difficile — associated diarrhea.  Her clinical focus includes treatment of refractory Clostridium difficile infection.

Dr. Lee leads two clinical trials assessing the use of FMT in gastrointestinal disease:

Clinical Focus

Dr. Lee’s clinical focus includes:

  • Treatment of viral hepatitis
  • Severe skin and soft tissue infections
  • Refractory Clostridium difficile infection
  • Chronic osteomyelitis, including vertebral
  • Prosthetic joint infections

Academic Interests

Dr. Lee is currently the Discipline Director of Microbiology for Hamilton Regional Laboratory Medicine Program (HRLMP) and formal Director of the Microbiology Residency Program at McMaster University.  She is also a member of the Hamilton Infection Control Committee, and Infections Research Group at St. Joseph's Healthcare.

Dr. Lee also teaches Nursing students and Medical Residents.  Her involvement in McMaster’s Medical program includes teaching:

  • Internal medicine Residents
  • Infections Diseases and Microbiology Residents
  • General Pathology Residents

Team Members

Research Associates

Christine Gauthier, Lynn Kelleher, Peter Kim

team photo

Selected Publications

Publications on FMT or areas related to C diff:

  • Kassam Z, Hundal R, Marshall JK, Lee CH. Fecal transplant via retention enema for refractory or recurrent Clostridium difficile infection. Arch Intern Med 2012;172(2):191-3.
  • Z Kassam, CH Lee, Y Yuan, RH Hunt.  Fecal Microbiota Transplantation for Clostridium difficile Infection:  Systematic Review and Meta-analysis.  Am J Gastroenterol.  2013:108; 500-508
  • Hundal R, Kassam Z, Johnstone J, Lee C, Marshall JK. Fecal transplantation for recurrent or refractory Clostridium difficile diarrhea. The Cochrane Library. Published Online: Sept. 7, 2011.
  • Tung JM, Dolovich LR, and Lee CH. Prevention of Clostridium difficile infection with Saccharomyces boulardii: A systematic review. Can J Gastroenterol 2009;23(12):817–821.
  • Lagrotteria D, Holmes S, Smieja M, Smaill F, and Lee C. Prospective, randomized inpatient study of oral metronidazole versus oral metronidazole and rifampin for treatment of primary episode of Clostridium difficile–associated diarrhea. Clin Infect Dis 2006;43 (5):547-552.
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