McMaster University

McMaster University

Boleslaw Lach


Pathology and Molecular Medicine

Division: Anatomical Pathology

Hamilton General Hospital
Hamilton, Ontario
905-527-0271 ext 46168

Boleslaw Lach

Faculty Biography

Education and Professional Standing

  • FRCPC Neuropathology, 1980
  • FRCPC Anatomical Pathology, 1976
  • MD, Academy of Medicine, Lodz, Poland, 1966


Research Focus

Dr. Lach’s research focus includes the following:

  • Encephalitis and other viral infections of the CNS
  • Pathology of mitochondrial encephalomyopathies
  • Muscle pathology
  • Neuro-Oncology

Academic Interests

Dr. Lach teaches neurosurgery, pathology and neurology residents.  He also participates in the “neuroblock” at the undergraduate level.

Selected Publications

  • Lach B, Haust MA. Nodular stromal lesions of choroid plexus in Hurler disease. Fetal and Pediatric Pathology. In Press.
  • Lach B, Tarnopolsky M, Nguyen C. Sacroplasmic hexogonally cross-linked tubular arrays immunostain for caveolin-3: an excess caveolinopathy? Acta Neuropathologica, 2009; 117(3):339-341.
  • Lach B, Hassounah M, Khafaga Y. Primary angiosarcoma of the brain in a child. Fetal and Pediatric Pathology, 2008; 27(3):175-183.
  • Lach B, Cupler EJ. Macrophagic myofasciitis in children is a localized reaction to vaccination. Journal of Child Neurology, 2008; 23(6):614-619.
  • Lach B, Benoit BG. Myofibroblastic sarcoma in meningioma: a new variant of “metaplastic” meningioma. Ultrastructural Pathology, 2007; 31(5):357-363.
  • Bouchama A, Roberts G, Al Mohanna F, El-Sayed r, Lach B, et al: Inflammatory, hemostatic and clinical changes in baboon experimental model for heat stroke. J Appl Physiol, 2005; 98(2):697-705.
  • Hassounah M, Lach B, Allam A, Al-Khalal H, Siddiqui Y, et al. Benign tumours of the human nervous system express high level of surviving and are resistant to spontaneous and radiation induced apoptosis. J Neuro-Oncology, 2005; 72(3):203-208.
  • Lach B, Al-Shail E, Patay Z. Spontaneous anaplasia in cerebellar astrocytoma. Brit Neurosurg, 2003; 17: 250-252.
  • Bohlega, B. Lach, B.F. Meyer, Y. Al Said, M. Kambouris, M. Al Homsi, E.J. Cupler. “Autosomal dominant hyaline body myopathy: Clinical variability and pathologic findings. Neurology, 2003; 61: 1519-23.
  • Duggal N, Lach B. Selective vulnerability of lumbo-sacral level of the spinal cord in anoxic-ischaemic myelopathy. Stroke: January, 2002.
  • Raymond L, Lach B, Shamji FM: Inflammatory aethiology of primary achalasia. Ultrastructural and immunohistochemical study. Histopathology, 1999; 35(5):445-453.
  • Bourque P, Lach B, Carpenter S, Rippstein P: New myopathy with hexagonal vesico-tubular cytoplasmic inclusions in muscle fibers. Annals of Neurol, 1999; 45:512-515.
  • Lach B, Gregor A, Rippstein P, Omulecka A: Angiogenic Histogenesis of Stromal Cells in Haemangioblastoma. Ultrastr. Pathol, 1999; 23:299-310.
  • DiMauro S, Bonilla, Servidei, Hughes, Lach B, et al. Exercise intolerance due to mutations in the cytochrome b gene of mitochondrial DNA. New Engl J,Med, 1999; 341:1037-1044.
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