McMaster University

McMaster University

Volodymyr (Vlad) Maksymov,

MD, PhD, FRCPC

Assistant Clinical Professor (Adjunct)
Pathology and Molecular Medicine

Grand River Hospital
835 King Street West
Kitchener, Ontario, Canada N2G 1G3

Phone: (519) 749-4300 Ext 2707
Fax: (519) 7494221
Volodymyr.maksymov@grhosp.on.ca

Faculty Biography

Education and Professional Standing

FRCPC, Anatomical Pathology (2009)

Residency: Memorial University of Newfoundland (2009)

MD, Lviv State Medical University, Lviv, Ukraine.

PhD, Moscow, High Educational Commission, Russia

Assistant Clinical Professor, McMaster University

Staff Pathologist, Grand River Hospital and St Mary’s General Hospital, Regional HPB Centre, Kitchener


Interests

Given the key anatomical relationships of the pancreas to the superior mesenteric artery (SMA) and superior mesenteric vein (SMV), and the bearing this has on surgical management over the last decade, we have been developed innovative approach to handling and assessment of the pancreaticoduodenectomy (Whipple) (PD) specimens, with emphasize on the margins status, as well as, we have been proponents of rigorous and thorough sampling of the SMA and SMV (groove) margins. Extensive sampling of margins/surfaces in PD specimens has revealed that invasion of the peripancreatic fat by single malignant glands without significant desmoplastic reaction is relatively common and may not be identified on gross examination (unless extensively sampled), or with imaging. This is important for quality assurance, including feedback to the radiologists and surgeons who make preoperative and intraoperative decisions as to the separation of vessels from the pancreatic head, especially in borderline resectable cases. 

Our proposal (clarification of terminology for the SMA margin, and inclusion of reporting of the SMV/portal vein/vascular groove surface/margin, as well as reporting the relationship of tumour to the anterior surface) are included in the new version of the CAP cancer reporting protocol. 

Clinical Focus

Pancreatic pathology

Academic interests

Dr Maksymov is involved in the Undergraduate Medical Program and Post-Graduate Residency Training Program at the Grand River Hospital (Waterloo campus of McMaster University).


Selected Publications

  • Maksymov V, M Hogan, Khalifa M A. An Anatomy-based mapping analysis of the pancreaticoduo-denectomy retroperitoneal margin highlights the urgent need for standardized assessment. Hepato Pancreato Biliary (HPB) (Oxford) 2013; 15 (3): 218-23. PMID: 23374362.
  • Maksymov V, Khalifa M A, Bussey A, Carter. B, M Hogan. Undifferentiated (anaplastic) carcinoma of the pancreas with intraductal growth pattern, morphological temporal heterogeneity: a case report and literature review. JOP. Journal of the Pancreas, 2011; 12(2): 170-6. PMID: 21386647.
  • Khalifa M A, Maksymov V, Rowsell C H. Retroperitoneal margin of the pancreaticoduo-denectomy specimen: anatomic mapping for the surgical pathologist. Virchows Archiv 2009; Volume 454, Number 2/ February:  125-131. PMID: 19066952.
  • Khalifa MA, Maksymov V, Rowsell CH, Hanna S. A novel approach to the intraoperative assessment of the uncinate margin of the pancreaticoduo-denectomy specimen.  Hepato Pancreato Biliary (HPB) (Oxford) 2007; 9:146-149. PPMID: 18333131.

Selected Presentations

  • 2015. Director of Workshop. 66th Annual Meeting of the Canadian Association of pathologists. Pathological Assessment of Pancreaticoduodenectomy (Whipple’s) Specimen (co-director D Driman). June 20-24, Montreal, Canada.
  • 2014. Director of Workshop. 65th Annual Meeting of the Canadian Association of pathologists. Pathological Assessment of Pancreaticoduodenectomy (Whipple’s)  Specimen (co-director D Driman). July 12-15, Toronto, Canada.
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