HIV infection; infections in immunocompromised hosts; diagnostic medical microbiology; infection control; infections in pregnancy; clinical epidemiology.
Dr. Smaill is actively involved in clinical trials in HIV management, the development of vaccines for tuberculosis, and management of infections in pregnancy. Her interest in HIV infection includes multicentre trials to evaluate efficacy and side-effects of different antiretroviral regimens and work on gender differences in the management of HIV infection. Dr. Smaill is also working with Dr. Xing on an adenovirus-based vaccine for tuberculosis and they are currently running a phase 1 clinical trial to evaluate their novel TB vaccine in healthy volunteers.
Dr. Smaill has an ongoing commitment to complete and update several Cochrane Systematic Reviews related to the management of infections in pregnancy, with a focus on treatment of asymptomatic bacteriuria and antibiotic prophylaxis for cesarean sections. She is an associate editor for ACP Evidence-Based Medicine. She is the co-editor of the recently published second edition of the textbook "Evidence-Based Infectious Diseases".
Education and Professional Standing
MSc Design, Measurement & Evaluation, McMaster University, 1997
FRCPC Medical Microbiology, 1988
FRCPC Infectious Diseases, 1987
FRCPC Internal Medicine, 1985
MBChB, Otago University (New Zealand) 1978
Research Coordinators: Sarah Culgin and Laura Puri
Research Nurse: Marcia Stirling