McMaster University

Medical Sciences
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Zainab Samaan

Zainab Samaan

Associate Professor

Research Interests

Dr. Zainab (Zena) Samaan is an Associate Professor, Department of Psychiatry and Behavioral Neurosciences, Associate Member, Department of Clinical Epidemiology and Biostatistics and Associate Faculty, Population Genomics Program, McMaster University. Dr. Samaan is also a staff psychiatrist, member of the Royal College of Psychiatrists, UK and Certified Academic Psychiatrist by The College of Physicians and Surgeons of Ontario. Dr. Samaan completed a Master’s in Science at the Dept. of Psychiatry, Trinity College Dublin, Ireland and further trained in psychiatric genetic epidemiology with Professors Peter McGuffin and Anne Farmer at the Institute of Psychiatry and Maudsley Hospital, London, UK where she obtained PhD in psychiatric genetics. Dr. Samaan is also a Staff Psychiatrist at St. Joseph’s Healthcare and Hamilton Health Sciences.

Her clinical interests are centered on the interface between psychiatry and medicine specifically, depression comorbidity with obesity and cardiovascular disease.

Corresponding research interests:

  1. Psychiatric genetics
  2. Comorbidity of depression with cardiometabolic disorders
  3. Addiction and suicide risk factors


McMaster University
St. Joseph's Healthcare

telephone: (905) 522-1155 ext. 36372

Program Area

Metabolism & Nutrition

Research Focus

Mental Health, Addiction, Clinical, Genetics

Selected Publications

  • The effectiveness of opioid substitution treatments for patients with opioid dependence: a systematic review and multiple treatment comparison protocol. Dennis BB, Naji L, Bawor M, Bonner A, Varenbut M, Daiter J, Plater C, Pare G, Marsh DC, Worster A, Desai D, Samaan Z, Thabane L. Syst Rev. 2014 Sep 19;3:105. doi: 10.1186/2046-4053-3-105.
  • Genetic influence on methadone treatment outcomes in patients undergoing methadone maintenance treatment for opioid addiction: a pilot study. Samaan Z, Bawor M, Dennis BB, Plater C, Varenbut M, Daiter J, Worster A, Marsh DC, Tan C, Desai D, Thabane L, Pare G.

    Neuropsychiatr Dis Treat. 2014 Aug 19;10:1503-8. doi: 10.2147/NDT.S66234. eCollection 2014.

  • Methadone induces testosterone suppression in patients with opioid addiction. Bawor M, Dennis BB, Samaan MC, Plater C, Worster A, Varenbut M, Daiter J, Marsh DC, Desai D, Steiner M, Anglin R, Coote M, Pare G, Thabane L, Samaan Z. Sci Rep. 2014 Aug 26;4:6189. doi: 10.1038/srep06189.