McMaster University

Medical Sciences
Graduate Program

Scope of Search


Anne Holbrook

Anne Holbrook


MD, PharmD, MSc, FRCP (C)

Research Interests

Research focuses on formulation, dissemination and implementation of best evidence regarding drug therapies, study of evidence vs clinical practice, interventions to improve informed decision-making by policy makers, clinicians and patients. Largest study examines impact of electronic decision support for chronic disease management on quality and efficiency of care, prescribing practices and privacy. Other studies examine the tailoring of benefit and harm information for individual patients, improving clinical trials particularly using complex interventions, patient preferences, quality of information needed and available for decision-making, medication safety, physician-pharmaceutical industry interactions, education in Clinical Pharmacology and Toxicology


St. Joseph's Healthcare,

50 Charlton Ave. E.

telephone: (905)522 1155 ext 35269


Program Area

Physiology & Pharmacology


Research Focus

Appropriateness of Prescribing,Medication Safety, Comparative Effectiveness and Safety, Randomized Trials, Drug Interactions, Prescribing competence

Selected Publications

1. Mei Wang · Anne Holbrook · Munil Lee · Jiayu Liu· Alvin Leenus · Nora Chen · Lawrence Mbuagbaw
Lehana Thabane. Barriers and facilitators to optimal oral anticoagulant management: a scoping review. Journal of Thrombosis and Thrombolysis. 2020.
2. Holbrook A, Bannerman H, Ahmed A, Georgy M, Liu JT, Troyan S, et al. Evaluation of a Novel Audit Tool for Medication Reconciliation at Hospital Discharge. The Canadian Journal of Hospital Pharmacy. 2019;72(6):421-7.
3. Muratov S, Lee J, Holbrook A, Guertin JR, Mbuagbaw L, Paterson JM, et al. Incremental healthcare utilisation and costs among new senior high-cost users in Ontario, Canada: a retrospective matched cohort study. BMJ Open. 2019;9(10):e028637.
4. Zhang XY, Holbrook AM, Nguyen L, Lee J, Al Qahtani S, Garcia MC, et al. Evaluation of online clinical pharmacology curriculum resources for medical students. Br J Clin Pharmacol. 2019; 85(11):2599-2604.