Dr. Chris Allen

Division of Respirology

Chris Allen


Associate Clinical Professor, Division of Respirology, Department of Medicine, McMaster University






Education and Professional Standing

Dr. Allen is an Associate Professor of Medicine at McMaster University.  His undergraduate education was at Oxford University in England and at the Royal London Hospital.  After postgraduate training which led to the MRCP (UK) diploma in General Internal Medicine Dr. Allen completed fellowship training in respiratory medicine at McMaster University.  This was followed by a Canadian MRC research fellowship in clinical exercise physiology at McMaster.  He joined the consultant staff at the Firestone Institute in 1984.

Research Interest

Pulmonary physiology and exercise testing, gastroesophageal reflux as it relates to respiratory disease, electronic database development to support the practice of respiratory medicine, community management of asthma through collaboration with the Primary Care Asthma Program which is funded and supported by the Ontario Ministry of Health..  Dr. Allen has received research funding from the Ontario Ministry of Health, the Ontario Lung Association, and the Canadian Institutes of Health Research.

Selected Publications

  1. Allen CJ, Jones NL.  Rate of change of alveolar CO2 and the control of ventilation during exercise.   J Physiol 1984;355:1-9.
  2. Allen CJ, Newhouse MT.  Gastroesophageal reflux and chronic respiratory disease.  Am Rev Resp Dis.  1984;129:645-7.
  3. Allen CJ, Jones NL, Killian KJ.  Alveolar gas exchange single breath analysis.  Journal of Applied Physiology 1984;57:1704-9.
  4. Anvari M, Allen CJ, Borm A.  Laparoscopic Nissen Fundoplication is a satisfactory alternative to long-term omeprazole. Br. J. Surg 1995;82:938-42.
  5. Anvari M, Allen CJ, Moran LA.  Immediate And Delayed Effects Of Laparoscopic Nissen Fundoplication On Pulmonary Function.  Surg Endosc 1996 10:1171-5.
  6. Kates N, Craven M.A., Crustolo A-M., Nikolaou N, Allen C, Farrar S.  Sharing care: the psychiatrist in the family physician’s office.  Can J Psychiatry 1997;42:960-65.
  7. Anvari M., Allen CJ.  Laparoscopic Nissen fundoplication two year comprehensive follow-up of a technique of minimal paraesophageal dissection.  Ann Surg 1998 Jan;227(1):25-32.
  8. Allen CJ, Anvari M.  Prospective Evaluation of Cough Before and After Laparoscopic Nissen Fundoplication.  Thorax 1998;53:963-8.  This paper discussed in an editorial Ing AJ, Ngu MC. Cough and gastroesophageal reflux. Lancet 1999;353:944-6.
  9. Allen, C. J. , Parameswaran, K. , Belda, J. & Anvari, M.  Reproducibility, validity, and responsiveness of a disease-specific symptom questionnaire for gastroesophageal reflux disease.  Diseases of the Esophagus2000:13 (4), 265-270.
  10. K. Parameswaran, M. Anvari, A. Efthimiadias, D. Kamada, FE. Hargreve, C. Allen.  Lipid-Laden Macrophages in Induced Sputum are a Marker of Oro-pharyngeal Reflux and Possible Gastric Aspiration.  Eur Respiratory J  2000 16(6):1119-1122.
  11. Parameswaran K, Allen CJ, Kamada D, Efthimiadis A, Anvari M, Hargreave FE. Sputum cell counts and exhaled nitric oxide in patients with gastroesophageal reflux, and cough or asthma. Can Respir J 2001;8(4):239-44.
  12. Anvari M, Allen C. Five-year comprehensive outcomes evaluation in 181 patients after laparoscopic Nissen fundoplication. J Am Coll Surg 2003;196(1):51-7.
  13. Allen CJ, Anvari M. Does laparoscopic fundoplication provide long-term control of gastroesophageal reflux related cough? Surg Endosc 2004;18(4):633-7.
  14. M.A. Craven,  L. Nikolaou, C.J. Allen, A.M. Crustolo, N. Kates.  Patient Education Materials for Mental Health Problems in Family Practice: Does Location Matter? Patient Education and Counseling 2005;56:192-196.
  15. Anvari M, Allen C, Marshall J, Armstrong D, Goeree R, Ungar W, et al. A randomized controlled trial of laparoscopic nissen fundoplication versus proton pump inhibitors for treatment of patients with chronic gastroesophageal reflux disease: One-year follow-up. Surg Innov. 2006 Dec;13(4):238-49
  16. D'Silva L, Cook RJ, Allen CJ, Hargreave FE, Parameswaran K. Changing pattern of sputum cell counts during successive exacerbations of airway disease. Respir Med. 2007;101(10):2217-20.
  17. Anvari M, Allen C, Marshall J, Armstrong D, Goeree R, Ungar W, et al. A randomized controlled trial of laparoscopic Nissen fundoplication versus proton pump inhibitors for the treatment of patients with chronic gastroesophageal reflux disease (GERD): 3-year outcomes. Surg Endosc. 2011;25(8):2547-54. Epub 2011/04/23.
  18. Goeree R, Hopkins R, Marshall JK, Armstrong D, Ungar WJ, Goldsmith C, et al. Cost-utility of laparoscopic Nissen fundoplication versus proton pump inhibitors for chronic and controlled gastroesophageal reflux disease: a 3-year prospective randomized controlled trial and economic evaluation. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. 2011;14(2):263-73. Epub 2011/03/16.
  19. Wilson AM, Nair P, Hargreave FE, Efthimiadis AE, Anvari M, Allen CJ. Lipid and smoker's inclusions in sputum macrophages in patients with airway diseases. Respir Med. 2011;105(11):1691-5. Epub 2011/08/13.

  20. Yao X, Gomes MM, Tsao MS, Allen CJ, Geddie W, Sekhon H. Fine-needle aspiration biopsy versus core-needle biopsy in diagnosing lung cancer: a systematic review. Curr Oncol. 2012;19(1):e16-27. Epub 2012/02/14.