Dominik Mertz

Division of Infectious Diseases

Dominik Mertz


Associate Professor, Division of Infectious Diseases, Department of Medicine

Medical Director Infection Control, Hamilton Health Sciences





Education and Professional Standing

Dr. Dominik Mertz, MD, MSc, FMH (CH), Associate Professor, attended medical school at the University Basel, Switzerland (1996-2002). He completed his training in Internal Medicine (2006) and Infectious Diseases (2009) in Switzerland and is board certified in both disciplines. He moved to Hamilton in August 2009 to complete a Master Degree in Health Research Methodology at McMaster University (2009-2011).

In June 2011, Dr. Mertz started as an Assistant Professor at McMaster University (Division of Infectious Diseases in the Department of Medicine and affiliated with the Department of Health Research Methods, Evidence, and Impact and the Department of Pathology and Molecular Medicine) and is serving as the Medical Director Infection Prevention and Control at Hamilton Health Sciences since. He was promoted to Associate Professor by July 2016.

His particular research interest is the epidemiology of hospital-acquired infections and of antibiotic-resistant pathogens, and antimicrobial stewardship. He published >60 peer reviewed articles to date. He is an associate editor for BMC Infectious Diseases and serves as the first-named editor for the 3rd edition of the book ‘Evidence-based Infectious Diseases’. He is teaching at the undergraduate (MD program), graduate (Health Research Methodology) and postgraduate level at McMaster University.

Research Areas and Clinical Focus:

  • Antimicrobial stewardship
  • Epidemiology and risk factors for resistance and infections by resistant bacteria
  • Prevention of C. difficile infection
  • Infection Control and Hospital Epidemiology

Honours and Grants:

  • Physician Service Incorporated Foundation (research funding)
  • Hamilton Health Sciences Early Career Award (2013-2016)
  • Lichtenstein Foundation (Basel, Switzerland)
  • Swiss National Science Foundation Research Fellowship (October 2009 to May 2011)
  • Swiss Society for Infectious Diseases Award 2009 for best epidemiological research

Selected Publications

  1. Mertz D, Whitlock R, Kokoszka AY, Swith SW, Carignan A, Rehan M, Jaffer IH, Alsagheir A, Loeb M. Routine surveillance versus independent assessment by an outcome adjudication committee in assessing patients for sternal surgical site infections after cardiac surgery. Infect Control Hosp Epidemiol; 37(5):600-602; 2016.
  2. Lytvyn L, Quack K, Banfield L, Johnston BC, Mertz D. Probiotics and synbiotics for the prevention of post-operative infections following abdominal surgery: a systematic review and meta-analysis of randomized controlled trials. J Hosp Infection. 2016: 92(2): 130-139
  3. Mertz D, Alawfi A, Pernica J, Rutherford C, Luinstra K, Smieja MJ. Clinical Severity of Pediatric Respiratory Illness with Enterovirus D68 as Compared to Rhinovirus or Other Enterovirus Genotypes: A Matched Cohort Study. CMAJ. doi: 10.1503/cmaj.150619; 2015.
  4. Irfan N, Brooks A, Mithoowani S, Celleti S, Mertz D. A Controlled Quasi-Experimental Study of an Educational Intervention to Reduce the Unnecessary Use of Antimicrobials For Asymptomatic Bacteriuria. PlosOne. 16;10(7):e0132071; 2015.
  5. Kasenda B, von Elm E, You J, Blümle A, Tomonaga Y, Saccilotto R, Amstutz A, Bengough T, Meerpohl J, Stegert M, Tikkinen KAO, Neumann I, Carrasco-Labra A, Faulhaber M, Mulla S, Mertz D, Akl EA, Bassler D, Busse JW, Ferreira-González I, Lamontagne F, Nordmann A, Gloy V, Raatz H, Moja L, Rosenthal R, Ebrahim S, Schandelmaier S, Sun X, Vandvik PO, Johnston BC, Walter MA, Burnand B, Schwenkglenks M, Hemkens L, Bucher HC, Guyatt GH, Briel M. Prevalence, characteristics, and publication of discontinued randomized trials. JAMA. 311(10): 1045; 2014.
  6. Srigley JA, Brooks A, Sung M, Yamamura D, Haider S, Mertz D. Inappropriate Use of Antibiotics and Clostridium difficile Infection. Am J Infect Control. 41(11):1116; 2013.
  7. Mertz D, Kim TH, Johnstone J, Lam PP, Science M, Kuster SP, Fadel S, Tran D, Fernandez E, Bhatnagar N, Loeb M. Populations at risk for severe or complicated influenza illness: a systematic review and meta-analysis. BMJ 347:f5061; 2013.
  8. Mertz D, Nuri K, O’Neill C, Loeb M. Algorithm to Reduce Unnecessary Isolation Days in Patients with a History of Colonization by Antimicrobial Resistant Organisms. Am J Infect Control. 41(11):1119; 2013.
  9. Mertz D, Johnstone J, Loeb M. Does duration of perioperative antibiotic prophylaxis matter in cardiac surgery? A systematic review. Ann Surg. 254(1):48-54; 2011.
  10. Mertz D, Frei R, Jaussi B, Battegay M, Flückiger U, Widmer AF. Exclusive Staphylococcus aureus throat carriage. At risk populations. Arch Intern Med. 169(2):172-178; 2009.