Division of Hematology & Thromboembolism

Irwin Walker


Professor, Division of Hematology & Thromboembolism, Department of Medicine

Associate Member, Department of Oncology

Director, Hamilton Bone Marrow Transplant Program

Director (Adults), Hamilton-Niagara Regional Hemophilia Program

Education and Professional Standing

  • MBBS, Melbourne University 1965
  • FRACP, Internal Medicine, 1970
  • FRCPC, Internal Medicine, 1972
  • FRCPC, Hematology, 1973

Research Interests

Dr. Walker has maintained a broad interest in hematology over many years. Most recently, in the field of bone marrow transplantation, he is a past-President of the Canadian Blood and Marrow Transplant Group, and has held a CIHR grant for the development of haploidential donor transplantation. Relating to hemophilia, he has held a series of grants relating to the development of hemophilia related software programs, the Canadian Hemophilia Registry, and epidemiological data relating to hemophilia.

He is a member of the World Federation of Hemophilia Data and Demographics Committee and together with his pediatric colleague, Dr. Anthony Chan, has “Twinned” the Hamilton Hemophilia Program with Belgrade, Serbia

Selected Publications

  1. Donald M Arnold, Jim A Julian, and Irwin R Walker. Mortality rates and causes of death among all HIV-positive individuals with hemophilia in Canada over twenty-one years of follow up. Blood First Edition Paper, prepublished online March 21, 2006; DOI 10.1182/blood-2005-11-4407
  2. Passweg JR, Walker I, Sobocinski KA, Klein JP, Horowitz MM, Giralt SA on behalf of the Chronic Leukemia Study Writing Committee of the International Bone Marrow Transplant Registry. Validation and extension of the EBMT Risk Score for patients with chronic myeloid leukaemia (CML) recieving allogenic haematopoietic stem cell transplants. British Journal of Hematology, 125:613-620, 2004.
  3. Walker I, Sigouin C, Sek J, Almonte T, Carruthers J, Chan A, Pai M, Heddle N., Comparing hand-held computers and paper diaries for haemophilia home therapy: A randomized trial. Haemophilia 10, 1-7, 2004.
  4. Walker I, Shehata, Nadine, Cantin Guy, Couture F, Dhedin N, Barty R, Foley R, Sutherland DR, Sigouin C, Schultz KR, Mitchell D., Canadian multicenter pilot trial of haploidentical donor transplantation. Blood, Molecules, and Diseases 33 222-226, 2004.
  5. Fraser, Graeme AM, Walker, IR, and Canadian Blood and Marrow Transplant Group. Cytomegalovirus prophylaxis and treatment after hematopoietic stem cell transplantation in Canada: a description of current practices and comparison with Centers for Disease Contro/Infectious Diseases Society of America/American Society for Blood and Marrow Transplantation guideline recommendations. Biology of Blood and Marrow Transplantation, vol 10, issue 5:287-297, 2004.