Division of Critical Care

Andreas P. Freitag


Professor Departments of Medicine & Pediatrics

Division Director Critical Care, Department of Medicine, McMaster University

Division Director, Respiratory Medicine, Hamilton Health Sciences

Staff Physician, Hamilton Health Sciences

ICU Director, MUMC Site

Medical Director Adult Cystic Fibrosis Program (Hamilton-Wentworth)

Medical Director, Adult and Pediatric Progressive Weaning Centres, MUMC, HHS


Education and Professional Standing

Research Interests

Dr. Freitag is a co-investigator in collaboration with several multi-centre clinical trials in critical care.  Current and recent collaboration include: Lung Open Ventilation Study (LOVS); Prophylaxis for Thromboembolism in Critical Care Trail (PROTECT), Oscillation for ARDS Treated Early (OSCILLATE), Dalteparin’s Influence on Renally Compromised: anti-Ten-A (DIRECT).

He is also a co-investigator in various clinical trials in cystic fibrosis.  He is involved in multi-centre Canadian trials looking at the prevalence of risk factors and management of osteoporosis in adult CF patients; mapping and isolation of genes influencing disease severity in CF; delivery systems and/or inhaled medications in CF.  Other areas of interest include management and surveillance of airway inflammation, energy requirements and expenditure, as well as exercise performance in CF patients.

Activities and Contributions

Dr. Freitag is a clinician-educator at McMaster University. He is the Divisional Director of Critical Care for the Department of Medicine and the ICU Site Director for clinical activities at the MUMC Site. He regularly teaches at an undergraduate and postgraduate level on topics of respiratory and critical care medicine.

His clinical practice includes critical care and respiratory medicine. He has an outpatient practice in adult and pediatric respiratory medicine, including specific clinical interests in cystic fibrosis and chronic respiratory failure. Throughout his clinical practice, he supervises learners of all levels including medical students and residents from numerous specialties.

Selected Publications

  1. Vandemheen KL, O’Connor A, Bell SC, Freitag A, Bye P, Jeanneret A, Berthiaume Y, Brown N, Wilcox P, Ryan G, Brager N, Rabin H, Morrison N, Gibson P, Jackson M, Paterson N, Middleton P, Aaron SD. Randomized trial of a decision aid for cystic fibrosis patients considering lung transplantation. Am J Resp Crit Care Med. 2009 Jul 9 (epub).
  2. Douketis J, Cook D, Meade M, Guyatt G, Geerts W, Skrobik Y, Albert M, Granton J, Hébert P, Pagliarello G, Marshall J, Fowler R, Freitag A, Rabbat C, Anderson D, Zytaruk N, Heels-Ansdell D, Crowther M; Canadian Critical Care Trials Group. Prophylaxis against deep vein thrombosis in critically ill patients with severe renal insufficiency with the low-molecular-weight heparin dalteparin: an assessement of safety and pharmacodynamics: the DIRECT study. Arch Intern Med. 2008 Sep 8; 168 (16): 1805-12.
  3. Cook D, Rocker G, Marshall J, Sjokvist P, Dodek P, Griffith L, Freitag A, Varon J, Bradley C, Levy M, Finfer S, Hamielec C, McMullin J, Weaver B, Walter S, Guyatt G; Level of Care Study Investigators and the Canadian Critical Care Trials Group. Withdrawal of mechanical ventilation in anticipation of death in the intensive care unit. N Engl J Med. 2003 Sep 18; 349 (12): 1123-32.

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