Division of Clinical Immunology and Allergy

Mark Larché


Professor, Division of Clinical Immunology & Allergy

Canada Research Chair, Allergy & Immune Tolerance




Education and Professional Standing

Dr. Larché completed his PhD in Immunology at the Royal Postgraduate Medical School, Hammersmith Hospital in 1990, under the supervision of Professor Mary A. Ritter. He spent 3 years in the USA at St. Jude Children’s Research Hospital, Memphis, TN as a postdoctoral fellow (Peter C. Doherty, Chairman).

On his return to the UK he joined the Immunology Department at St. Mary’s Hospital Medical School (Jonathan R. Lamb, Chairman), prior to joining the faculty of the National Heart and Lung Institute (A. Barry Kay, Chairman) which later became a Division of the Faculty of Medicine of Imperial College.

Research Interests

Mark Larché is Canada Research Chair in Allergy & Immune Tolerance and Professor in the Department of Medicine at McMaster University. Larché is also Honorary Professorial Research Fellow in the Faculty of Medicine at Imperial College, London, UK from where he recently (Sept 2006) made the move to Canada. In 2004 he was a Distinguished Visiting Professor at the University of Manitoba, Canada.

From 2001-2006 he was an Asthma UK Senior Research Fellow. He is a former member of the Medical Research Council New Investigator Awards (NIA) Panel, the MRC College of Experts (Physiological Systems and Clinical Sciences Board) and the Asthma UK Research Committee. He was Chairman of the Asthma Section of the European Academy of Allergology and Clinical Immunology (EAACI) from 2001-2005, a member of the EAACI Executive Committee (2001-2005) and a member of the BSI Vaccine Affinity Group Board (2003-2006).

Larché is an Associate Editor of Respiratory Research and a member of the editorial board of Clinical Experimental Immunology and Clinical Experimental Allergy.

He is a member of the AllerGen Network of Centres of Excellence and numerous professional societies including the Institute of Learning and Teaching, the British Society for Immunology, the British Society of Allergy and Clinical Immunology, the European Academy of Allergology and Clinical Immunology, the American Academy of Allergy, Asthma and Immunology, the Collegium Internationale Allergologicum.

Together with Professor AB Kay, he founded “Circassia Ltd.”, a biotechnology company to develop vaccines for allergic diseases. Research interests extend beyond asthma and allergies into transplantation, coeliac disease and autoimmune diseases.

Selected Publications

Dr. Larché has authored over 100 scientific papers and has been the recipient of several international prizes for his work including “The Respiratory 2000 International Young Investigator Award”, “The Henning Lowenstein Research Award 2000” and the "Pharmacia Allergy Research Foundation Award" in 2001.