McMaster University

McMaster University

Faculty of
Health Sciences

Canada Research Chair in Aging and Immunity

Dawn Bowdish

Research Involves

It is unclear why susceptibility to bacterial pneumonia begins to increase in middle age (i.e 55 yrs). However, these infections become increasingly common and costly to treat with age. In addition, acquiring bacterial pneumonia in mid- or late-life often exacerbates or accelerates sub-clinical or existing chronic inflammatory conditions, decreasing the quality of life and increasing the cost of care.

This proposal investigates the mechanisms of susceptibility to the major causative agent of pneumonia in the elderly, Streptococcus pneumoniae, and the interplay between age associated inflammation, chronic inflammatory diseases and the anti-bacterial response, targeting age-associated inflammation as a novel therapeutic target.

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