MacOrtho is a world leader in clinical research in the field of orthopaedic surgery. Under the leadership of Dr. Mohit Bhandari, MacOrtho research is at the forefront of a paradigm shift in how orthopaedic research is being conducted world-wide. Ten years ago, orthopaedic surgery trials were typically single-centre initiatives which included too few patients to yield definitive answers on clinically important questions. In the past ten years, Dr. Bhandari and the MacOrtho team have helped to change how research is being conducted by leading the largest trials in the world in the field of orthopaedic surgery, thereby setting the benchmark for all future clinical research. Clinician Scientists within MacOrtho have thrived under Dr. Bhandari’s mentorship and promotion, making MacOrtho a leading academic institution for research in the field of orthopaedic surgery.