McMaster University

Fragile X and Autism
Research (FXAR)

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Neurosphere

Team News

  • 2017
  • 2016
  • 2015
  • 2014

May 2017

 

Summer students Amanda Poxon, Chloe Wong and Danish Ayub joined the Doering Lab.

 

July 2017

 

Publication by the Doering Lab in Brain Research. "Abnormal neural precursor cell regulation in the early postnatal Fragile X mouse hippocampus". Brain Research 2017, Volume 1666, 1 July, Pages 58-69.


February 2016

Publication by the Doering Lab in International Innovation. "The Role of Astrocytes in the Developing Brain".

March 2016

Publication by the Doering Lab in Neuroscience. "Hippocampal neuronal subtypes develop abnormal dendritic arbors in the presence of Fragile X astrocytes". Neuroscience, Volume 324, 2 June 2016, Pages 202–217.

April 2016

Dr. Shivraj Singh (Post-doctoral fellow) recruited to the Doering lab (April 1, 2016). Dr. Singh brings technical expertise in flow cytometry, microscopy, immunoassays and optogenetics to the project.

May 2016

The FRAXA Research Foundation renewed the post-doctoral fellowship for a second year to Dr. Angela Scott.

Publication by the Doering Lab in Frontiers in Cellular Neuroscience. "Astrocyte-Secreted Factors Selectively Alter Neural Stem and Progenitor Cell Proliferation in the Fragile X Mouse". Frontiers in Cellular Neuroscience, 18 May 2016.

June 2016

Dr. Doering, Dr. Scott and Jessica Wallingford presented at the Gordon Research Conference: Fragile X and Autism-Related Disorders - New Insights into Disease Mechanisms Leading to Improved Therapeutics for Neurodevelopmental Disorders held June 5-10 in Mount Snow, West Dover, VT.

August 2016

Publication by the Doering Lab in Molecular Brain. "Astrocyte-secreted thrombospondin-1 modulates synapse and spine defects in the fragile X mouse model". Molecular Brain 20169:74
DOI: 10.1186/s13041-016-0256-9.

September 2016

New graduate students (Kathryn Reynolds and Victoria Krasovska) joined the Doering lab.

November 2016


Dr. Doering and lab members attended the Society for Neuroscience annual Meeting in San Diego, CA from November 12th to 16th. A poster presentation was made by Angela Scott.

 

Abstract Link for the 2016 poster presentation

Drs. Doering, Scott, Haghighi and Zhuo met in San Diego to discuss research progress and plan future developments.

 

 

 

 

 

 

January 2015

Phase 2 of the Azrieli Neurodevelopmental Research Program was announced December 18, 2015.

[Details about Phase 2 of the Azrieli Neurodevelopmental Research Program]

This funding will be under the Brain Canada's Multi-Investigator Research Initiative (MIRI) latform Support Grants (PSGs) programs.


February 2015

Dr. Angela Scott (Post-doctoral fellow) recruited to the Doering lab (April 1, 2015 start date). Dr. Scott brings technical expertise in molecular (qPCR, Western blotting, in situ hybrization), cellular (immunocytochemistry, calcium imaging, amperometry recording) and behavioral assays to the project.


March 2015

The FRAXA Research Foundation awarded a post-doctoral fellowship to Dr. Angela Scott.

[Details on the complete list of 2015 FRAXA Grants for Fragile X Research]


April 2015

Undergraduate summer student Huaying (Helen) Zhao joined the Doering lab.


May 2015

Undergraduate summer student Kimberley Young joined the Haghighi lab.


October 2015

Dr. Doering and lab members attended the Society for Neuroscience annual Meeting in Chicago, IL from October 17th to 21th. Poster presentations were made by Connie Cheng, Mary Sourial, Jessica Wallingford and Angela Scott.

Abstract Links for 2015 poster presentations

The annual meeting provided an opportunity for Drs. Doering, Haghighi, Zhuo and Nelson to discuss research progress and plan future developments

April 2014

Subsequent to the official start date of April 1, 2014, Dr. Doering met with Dr. Zhuo at the University of Toronto. The discussions established an initial plan to develop pilot studies exploring the electrophysiological effects of TSP-1, Hevin and Glypican in the cerebral cortex of selected mice.


May 2014

May 1 marked the official announcement of the grant recipients funded through the Azrieli Foundation and Brain Canada $7.5 million partnership. The announcement was made at the Palais des Congres de Montreal by Prime Minister Stephen Harper.

The annual Canadian Association for Neuroscience (CAN) meeting (May 25-28) provided an opportunity for Dr. Doering to meet Dr. Haghighi in Montreal. Very meaningful talks sorted out strategic starting points to examine glial influences on synaptic structure in the Fragile X fly model.


July 2014

Graduate students Connie Cheng and Mary Sourial attended the 14th International Fragile X Conference from July 16-20 in Orange County, California to present their latest Fragile X research results. Their abstracts are listed on page 12 of the conference agenda.

September 2014


New personnel recruited to the labs include Jessica Wallingford (MSc. graduate student) to the Doering lab and Dr. Mario Ramiro Calderon (Post-doctoral fellow) to the Haghighi laboratory. Post-doctoral position in the Doering laboratory in glial neurobiology and Fragile X/autism advertised with the Canadian Association for Neuroscience.


October 2014

Post-doctoral position in the Doering laboratory posted with the Society for Neuroscience (NeuroJobs Career Center. Potential applicants will be able to meet with Dr. Doering at the annual Society for Neuroscience meeting in Washington, DC.


November 2014

Dr. Doering and graduate students Connie Cheng and Mary Sourial attended the Society for Neuroscience annual meeting in Washington, DC from November 15th to 19th.  Poster presentations from the Doering lab were made by Connie Cheng and Mary Sourial.

Abstract Links for 2014 poster presentations

The annual meeting provided an opportunity for Drs. Doering, Haghighi and Nelson to discuss ongoing research in their labs and to initiate future experiments.

 

 

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