Sample Preparation

• Chemical Processing
• Cryofixation
• Freeze substitution
• Ultramicrotomy
• Cryo-ultramicrotomy
• Thin film supports

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Analytical

• Microanalysis and mapping of elements
• Electron diffraction of crystals

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Confocal EM

• Laser optical sectioning
• Fluorescent microscopy
• Transmission/reflected microscopy
• Digital image acquisition

Transmission EM

Ultrastructure

• Biological cells/tissue
• Polymers
• Viruses
• Small molecules
• Metalurgical Samples

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Scanning EM

• Surface ultrastructure
• Particle sizing
• Heavy atom contrast imaging (backscatter)

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Immuno-Labelling

• LM and EM level
• Pre and post embedding
• Cryo-section labelling

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Image Analysis

• Morphometry
• Particle-sizing/counting
• 3D reconstruction