McMaster University

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Researchers

Sonia Anand

Sonia Anand

Dr. Sonia Anand is a Professor of Medicine and Epidemiology at McMaster University, the Director of McMaster Population Genomics Program and a vascular medicine specialist. She also holds the Canada Research Chair in Ethnic Diversity and Cardiovascular Disease and the Heart and Stroke Foundation of Ontario/Michael G. DeGroote Chair in Population Health Research. Her present research focuses upon the environmental and genetic determinants of vascular disease in populations of varying ancestral origin, women and cardiovascular disease.

Past education includes an undergraduate degree in Life Sciences from Queen’s University in 1989, a Doctor of Medicine from McMaster in 1992, Internal Medicine Training at McMaster and a Fellowship of the Royal College of Physicians and Surgeons of Canada in 1996. She further received her Masters in Clinical Epidemiology at McMaster in 1996 and Ph.D. in Health Research Methodology at McMaster in 2002. She completed a Heart and Stroke Foundation of Canada Research Fellowship in 1998, and in 2001 completed a Vascular Medicine Fellowship at Harvard University’s Brigham and Women's Hospital.

In 1996, Dr. Anand received a Canadian Institutes of Health Research Clinician Scientist Award Phase 1 followed by the Phase 2 Award which she held from 2003-2008. She held the Eli Lily/May Cohen Chair in Women’s Health Research at McMaster from 2006-2013. Dr. Anand’s work is widely published amongst academic and peer-evaluated journals and she teaches clinical epidemiology courses in methodology and cardiovascular disease at McMaster University.

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Rahul Chanchlani

Rahul Chanchlani

Dr. Rahul Chanchlani is an Associate Professor in the Division of Nephrology, Department of Pediatrics at McMaster Children’s Hospital. After finishing his initial medical training from India, he completed a clinical fellowship in pediatric nephrology at the Hospital for Sick Children, Toronto, and also pursued a Master's in Clinical Epidemiology and Clinician Investigator Program from the University of Toronto. He is an associate faculty in the Department of Health Research Methods, Evidence, and Impact (HEI), and cross appointed as a Scientist at ICES and at the Population Health Research Institute (PHRI), McMaster University.

Dr. Chanchlani is one of the 14 participants selected from 12 countries by the International Society of Nephrology for the Emerging Leader’s Program, which helps early-career nephrologists to become qualified for a leadership role in the advancement of global kidney care. In addition to clinical and teaching commitments, Dr. Chanchlani has an established research program that aims to promote interdisciplinary collaborations among peers and experts to address key knowledge gaps in common kidney diseases such as acute kidney injury, kidney transplantation, hypertension and nephrotic syndrome among children. As principal investigator, his research program is supported by grants from various local, provincial and national organizations including CIHR and Kidney Foundation of Canada. He has so far published more than 50 peer-reviewed papers and has supervised learners at all levels of training.

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Joseph Beyene

Joseph Beyene

Dr. Joseph Beyene is an Associate Professor of Biostatistics and the John D. Cameron Endowed Chair in the Genetic Determinants of Chronic Diseases, Department of Health Research Methods, Evidence, and Impact, McMaster University. He was recently a Senior Scientist in the Research Institute of the Hospital for Sick Children. He currently holds an adjunct faculty position as Associate Professor of Biostatistics at the University of Toronto in the Dalla Lana School of Public Health and the Institute of Health Policy, Management and Evaluation, and Adjunct Scientist at the Hospital for Sick Children.

His research is funded by the Natural Sciences and Engineering Research Council of Canada (NSERC) and the Canadian Institutes of Health Research (CIHR). He has a broad research interest around statistical method development and application including statistical genetics, systematic reviews/meta-analyses, predictive modeling, health technology assessment, and clinical research. His current work focuses on developing and applying novel data integration statistical methods using heterogeneous sources of data. Dr. Beyene's scientific and clinical application areas span a wide range of disciplines including infectious diseases, rheumatology, oncology, and cardiovascular diseases.

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Russell de Souza

Dr Russell de Souza

Dr. Russell de Souza, RD, ScD is an Assistant Professor in the Department of Health Research Methods, Evidence, and Impact. As a nutrition epidemiologist, Dr. de Souza's current research interests lie in advancing methodology for systematic reviews and meta-analysis and clinical trials in the field of nutrition, with an interest in the role of dietary patterns and macronutrients (specifically fructose, saturated and trans fats) in chronic disease risk.

Dr. de Souza is also involved with the Diet and Gene Interaction Study (DIGEST) pilot trial to examine the mechanism underlying the interaction between fruits and vegetables and 9p21 variants on risk of heart disease, and two cohorts: the Alliance for Healthy Hearts and Minds, and the Birth Cohort Alliance, which are investigating the impact of neighbourhood-level risk factors and early life exposures on chronic disease incidence and risk factors.

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Guillaume Paré

Guillaume Pare

Dr. Guillaume Paré is Assistant Professor of Pathology & Molecular Medicine at McMaster University and Director of the Genetic and Molecular Epidemiology Laboratory, as well as Deputy Director of the Clinical Research & Clinical Trials Laboratory for Hamilton Health Sciences. Dr. Paré is a Medical Biochemist with board certification from the Royal College of Physicians and Surgeons of Canada. He completed a Master’s in Human Genetics at McGill University.

He further trained in genetic epidemiology at Harvard Medical School. Dr. Paré currently holds a Canada Research Chair in Genetic and Molecular Epidemiology. Dr. Paré was presented the ‘Mrs. Asha Verma Memorial Translational Lectures in Cardiovascular Medicine Award’ in September 2013.  Dr. Paré was also the recipient of the CIHR Maud Menten award for outstanding research as a new clinician-scientist in 2010, and was a finalist in 2012.

His clinical interests are centered on lipoprotein disorders, obesity and cardiovascular disease prevention. His corresponding research interests are in cardiovascular genetics, biomarker development and pharmacogenomics. These interests have led to expertise in bioinformatics, high-throughput biology and genetic epidemiology. His latest contributions are the characterization of the common genetic determinants of clopidogrel efficacy, inflammatory markers and lipoprotein fractions, as well as development of novel statistical tools for analysis of genetic datasets.

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Jackie Bosch

Jackie Bosch

Dr. Jackie Bosch is an occupational therapist with a clinical interest in functional outcomes and improving outcomes after stroke. She the Assistant Dean of the McMaster Occupational Therapy Program, a full-time faculty member in the School of Rehabilitation Science and an Investigator at the Population Health Research Institute, McMaster University.

She has focussed her research efforts on the conduct of large, multinational clinical trials in the areas of primary and secondary cardiovascular disease and diabetes prevention Dr. Bosch is interested in the design of clinical research and in improving the efficiency of conducting clinical trials and has been involved in the Sensible Guidelines working group to improve key aspects or research implementation. She has been a faculty member of the international Clinical Trials courses offered by PHRI and has co-chaired the Canadian Initiative to Streamline Clinical Trials.

Dr. Bosch’s clinical interest is in the area of functional outcomes, and she has worked with colleagues to develop functional outcome measures used in several large, international trials, to try and understand the effect of interventions on functional as well as clinical outcomes. She is currently co-principal investigator of a large observational study examining clinical and functional outcomes of gastrointestinal bleeding.

Since 2014 she has been the co-principal investigator on the OSCAIL (Organized Stroke Care Across Income Levels) which was designed to determine if key aspects of organized stroke care could be implemented in low resources settings to improve outcomes after stroke. The study demonstrated that small, inexpensive changes to stroke care could make important difference in outcomes. These findings need to be replicated on a larger scale. The study also demonstrated the need for community-based stroke care, as stroke survivors in low resource settings are discharged home with very little or no follow up or rehabilitation. The OSCAIL group has now grown to investigators from 8 countries (five low resource countries) and has made important connections with other groups working to improve outcomes after stroke in low in come settings. The group is developing studies for both the hospital and community settings and is working with Stroke Survivor Organizations (SSO) to develop sustainable community-based support and rehabilitation for stroke survivors and their families.

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Zena Samaan

Zena Samaan

Dr. Zainab (Zena) Samaan is a Professor of the Department of Psychiatry and Behavioral Neurosciences, an Associate Member of the Department of Health Research Methods, Evidence, and Impact, and an Associate Faculty in the Population Genomics Program in McMaster University. Dr. Samaan is also a Staff Psychiatrist, member of the Royal College of Psychiatrists, UK and Certified Academic Psychiatrist by The College of Physicians and Surgeons of Ontario.

Dr. Samaan completed a Master’s in Science at the Department of Psychiatry, Trinity College Dublin, Ireland and further trained in psychiatric genetic epidemiology with Professors Peter McGuffin and Anne Farmer at the Institute of Psychiatry and Maudsley Hospital, London, UK where she obtained her PhD in psychiatric genetics. Dr. Samaan is also a Staff Psychiatrist at St. Joseph’s Healthcare and Hamilton Health Sciences.

Her clinical interests are centered on the interface between psychiatry and medicine, in particular depression comorbidity with obesity and cardiovascular disease. Her corresponding research interests are in psychiatric genetics, comorbidity of depression with cardio metabolic disorders, addiction and suicide risk factors.

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Gita Wahi

Gita Wahi

Dr. Gita Wahi is an Associate Professor in the Department of Pediatrics at McMaster University and a pediatrician at McMaster Children’s Hospital. Her clinical focus includes the treatment of pediatric obesity within the Children’s Exercise and Nutrition Centre. Her research interests focus on the contribution of the early life environment to the trajectory of childhood obesity and related cardiovascular risk factors among diverse ethnic groups. She co-leads the Indigenous Birth Cohort study. Her work is supported by the CIHR and Early Career award from the Hamilton Health Sciences’ Foundation.

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