Cancer, heart disease, stroke and brain health all impact the quality of life of people living in Canada, and also increase the cost of health care. This study is being conducted to better understand the early causes and risk factors of these conditions and to learn how they progress to the disease states.
The primary goal of the Aboriginal Birth Cohort (ABC) study is to determine the causes of fat gain among Aboriginal newborns and the growing offspring during the first three years of life.
The purpose of the Diet & Gene Interaction Study (DIGEST) is to test the feasibility of a dietary intervention where food is provided for 2 weeks to determine the amount of change in gene expression and biochemical markers of inflammation in response to a prudent diet compared to a typical North American diet.
The NutriGen Alliance will study the interplay among 4 factors: gene expression, maternal and infant nutrition, and the infant gut bacteria; and the role they play in childhood health. Our findings will provide a solid evidence base to inform Dietary Guidelines in pregnancy, the development of randomized clinical trials to provide additional high quality evidence, and will be relevant to diverse and high-risk populations of Canada.
GENOA (Genetics of Opioid Addiction) is a research collaborative between the Ontario Addiction Treatment Center (OATC) and the Population Genomics Program in the Faculty of Health Science at McMaster University. This research collaborative seeks to answer questions pertaining to the impact of genetic variants on response to methadone for patients seeking treatment for opioid addiction.