The research focus for the Centre is the general area of mammalian functional genomics. CFG faculty members are particularly interested in developing new technologies to ascertain the function of genes at the cellular and organismal level. Our experimental organism of choice is the laboratory mouse and cultured cells derived from various mammalian species, including humans. Due largely to the research interest of the CFG’s core faculty, our principal research focus is in the area of human diseases, especially cancer. The Centre is also interested in developing new functional genomics tools to rapidly define protein function in mammalian cells. This includes the development of new methods to validate the participation of specific genes in diseases that are identified using expression profiling and proteomic technologies.