Health Research Methods, Evidence, and Impact

Holger Schünemann
MD (Hanover, Germany), MSc (Buffalo), PhD (Buffalo)

Professor and Chair, Department of Health Research Methods, Evidence, and Impact

Michael Gent Chair in Healthcare Research

Professor of Medicine

Editor-in-chief, BMC Health and Quality of Life Outcomes

Professor, University at Buffalo, Department of Medicine

Visiting Professor, University of Freiburg, Germany

+ 1 905 525 9140 x 24931
+ 1 905 522-9507 for official department email for research and other email

Administrative Assistant: Charmaine Fraser x 24931

Department of Health Research Methods, Evidence, and Impact
McMaster University Health Sciences Centre, Room 2C16
1280 Main Street West
Hamilton, ON  L8S 4K1, Canada


Academic Interests

Dr. Schünemann has assumed the role of chair of the department on February 1, 2009. He also is one of two chairs of the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. This international working group developed a common grading system for evaluating the quality of evidence and strength of recommendations for recommendations in health care. Dr. Schünemann is editor-in-chief of Health and Quality of Life Outcomes and co-convenor of the Applicability and Recommendations Methods Group of the Cochrane Collaboration. At McMaster he works with the CLARITY research group. His research interests are guideline development, systematic reviews, health related quality of life, pulmonary function and respiratory disease epidemiology and knowledge translation.

Selected Publications

  1. Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, Schünemann HJ. GRADE: An Emerging Consensus on Rating Quality of Evidence and Strength of Recommendations. BMJ 26;336(7650):924-6, 2008
  2. Guyatt GH, Oxman AD, Kunz R, Jaeschke R, Helfand M, Vist GE, Schünemann HJ. Grading Recommendations: Incorporating considerations of resources use. BMJ 24;336(7654):1170-3, 2008
  3. Guyatt GH, Oxman AD, Kunz R, Falck-Ytter Y, Vist GE, Liberati A, Schünemann HJ. Going from evidence to recommendations. BMJ 336(7652):1049-51, 2008
  4. Schünemann HJ, Oxman AD, Brozek J, Glasziou P, Jaeschke R, Vist G, Williams J, Kunz R, Craig J, Montori V, Bossuyt P, Guyatt GH. GRADEing the quality of evidence and strength of recommendations for diagnostic tests and strategies. BMJ 336;1106-1110, 2008
  5. Guyatt GH, Oxman AD, Kunz R, Vist GE, Falck-Ytter Y, Schünemann HJ. What is ‘quality of evidence’ and why is it important to clinicians? BMJ 336;995-998, 2008
  6. Schünemann HJ, Cook D, Guyatt G. Methodology for Antithrombotic and Thrombolytic Therapy Guideline Development: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 133: 113S–122S, 2008
  7. Akl EA, Kamath G, Sperati F, Kim SY, Yosuico V, Barba M, Cook DJ, Schünemann HJ. Low Molecular Weight Heparin versus Unfractionated Heparin for perioperative thromboprophylaxis in patients with cancer: a systematic review. Archives of Internal Medicine 23;168(12):1261-9, 2008
  8. Schünemann HJ, Woodhead M, Anzueto A, Buist S, MacNee W, Rabe K, Heffner J. A vision statement on guideline development for respiratory disease: the example of COPD. The Lancet 373: 774-779.
  9. Akl EA, Schunemann HJ. Routine heparin for cancer patients? One answer and more questions. NEJM Feb 16;366(7):661-2, 2012.
  10. Hsu J, Santesso N, Mustafa R, Brozek J, Chen Y, Hopkins J, Cheung A, Hovhannisyan G, Ivanova L, Flottorp S, Sæterdal I, Wong A, Tian J, Uyeki TM, Akl EA, Alonso-Coello P, Smaill F, Schunemann HJ. Antivirals for Treatment of Influenza: A Systematic Review and Meta-analysis of Observational Studies. Annals of Internal Medicine. 2012;156:512-24.

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