McMaster University

McMaster University

Shangguo Tang


Associate Professor
Pathology and Molecular Medicine

Division: Anatomical Pathology

McMaster University
2N27 Health Sciences Centre
905-521-2100 ext. 42019

photo of dr tang

Faculty Biography

Education and Professional Standing

  • FRCPC, Anatomical Pathology, 2007
  • FCAP, 2005
  • FASCP, 2005
  • Fellowship, Cytopathology, Hahnemann University Hospital, Drexel University, 2005-2006
  • Residency, Combined Anatomical/Clinical Pathology Program,Hahnemann University Hospital, Drexel University, 2001-2005
  • MD, Luzhou Medical College, Sichuan, China, 1983
  • MSc, West China University of Medical Sciences, Chengdu, Sichuan, China, 1987


Clinical and Research Focus

As an Anatomical Pathologist, Dr. Tang provides service through the Hamilton Regional Laboratory Medicine Program. His special interests include cytopathology, breast pathology and gynecologic pathology.  Dr. Tang's research interests are in cytopathology and breast/gynecological malignancy.

Academic Interests

As a resident cytopathology rotation supervisor and site supervisor at McMaster University Medical Centre, Dr. Tang is actively involved in the Undergraduate (MD) and Postgraduate Medicine Educational Programs.  He also acts as supervisor to undergraduate students working on summer research projects.

Selected Publications

Selected Publications

Abdel-Mesih A, Daya D, Onuma K, Sur M, Tang S, Akhtar-Danesh N, Boutross-Tadross O, Ceballos KM, Chapman W, Colgan T, Deb P, Nucci MR, Oliva E, Lytwyn A. Interobserver Agreement for Assessing Invasion in Stage 1A Vulvar Squamous Cell Carcinoma. Am J Surg Path 2013; 37(9):1336-41.

Mahe E, Tang S, Deb P, Sur M, Lytwyn A, Daya D. Do deeper sections increase the frequency of detection of serous tubal intraepithelial carcinoma (STIC) in the "sectioning and extensively examining the FIMbriated end" (SEE-FIM) protocol? Int J Gynecol Path 2013; 32(4):353-7.

Leung VA, Tang S, Mahe E, Patlas MN. Littoral cell angioma: diagnosis by image-guided biopsy.Ann Cli Lab Sci. 2012 42(4):417-421.

Yu RS, Abedi SM, Ezzat T, Parasu N, Tang S, Lightheart M. Massive leiomyomatous uterus presenting as bilateral pulmonary emboli. Anatol J Obstet Gynecolo 2012; 2:2.

Tang S, Onuma, K, Deb P, Wang E, Mahe E, Sur M and Daya D. Frequency of Serous Tubal Intraepithelial Carcinoma in Various Gynecological Malignancies-A Study of 300 Consecutive Cases. Int J Gynecol Path, 2012; 31:103-110.

Quinlan -Davidson S, Hodgson N, Elavathil L, Tang S. Borderline Phyllodes Tumor with an Incidental Invasive Ductal Carcinoma and Lobular Carcinoma In-Situ Component: A Case Report”. J Breast Cancer. 2011; 14(3):237-240.

He SH, Chen X, Song CH, Liu ZQ, Zhou LF, Ma WE, Zhao LD, Li TL, Tang SG, Xing Z, Yang PC. Interferon- λ-mediates oral tolerance and inhibits antigen-specific, T-helper 2 cell-mediated inflammation in mouse intestine. Gastroenterology. 2011; 141:249-258. 2011.

Feng BS, Chen X, Li P, Zheng PY, Chong J, Cho DB, He SH, Tang SG and Yang PC. Expression of integrin alphavbeta6 in the intestinal epithelial cells of patients with inflammatory bowel disease. North Am J Med Sci. 2009; 1: 200-204. 2009.

Zheng PY, Feng BS, Oluwole C, Solderholm J, Chen X, Li P, Tang SG and Yang PC. Eosinophil-derived corticotrophin releasing hormone links impact of psychological stress to gut epithelial barrier dysfunction. Gut. 58; 1473-1479. 2009.

Chen X, Feng BS, Zheng PY, Liao XQ, Chong J, Tang SG and Yang PC. 2008. Fc gamma receptor signaling in mast cells links microbial stimulation to mucosal immune inflammation in the intestine. Am J pathology 173 (6): 1647-1656.

Tang S, Le-Tien H, Goldstein BJ, Shin P, Lai R, and Fantus, IG. 2001. Decreased in situ insulin receptor dephosphorylation in hyperglycemia-induced insulin resistance in rat adipocytes. Diabetes. 50(1):83-90.

Tang S, Beharry S, Kent G and Durie PR. 1999. Synergistic effects of cyclic AMP- and calcium-mediated amylase secretion in isolated pancreatic acini from cystic fibrosis mice. Pediatr Res 45(4):482-488.

Tang S, Lu B, and Fantus IG. 1998. Stimulation of 125I-transferrin binding and 59Fe uptake in rat adipocytes by vanadate: Treatment time determines apparent tissue sensitivity. Metabolism 47(6):630-636.

Tang S, Beharry S and Durie PR. 1997. Postnatal development of the rat exocrine pancreas. I. Alterations in high- and low-affinity cholecystokinin receptors and enzyme secretion. Pancreas 15:325-334.

Tang S, Beharry S and Durie PR. 1997. Postnatal development of the rat exocrine pancreas. II. Effects of protein-calorie malnutrition on amylase secretion and CCK receptor binding. Pancreas 15:335-344.

Fantus IG, George R, Tang S, Chong P and Poznansky MJ. 1996. The insulin-mimetic agent vanadate promotes receptor endocytosis and inhibits intracellular ligand-receptor degradation by a mechanism distinct from the lysosomotropic agents. Diabetes 45:1084-1093.

Fantus IG, Deragon G, Lai R and Tang S. 1995. Modulation of insulin action by vanadate: evidence of a role for phosphotyrosine phosphatase activity to alter cellular signaling. Mol Cell Biochem 153:103-112.


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