McMaster University

McMaster University

Marek Smieja


Professor, Pathology and Molecular Medicine

Division: Clinical Pathology (Microbiology)

Associate Member: Medicine
Associate Member: Clinical Epidemiology and Biostatistics
Microbiologist & Infectious Diseases Physician

Head of Virology, Hamilton Regional Laboratory Medicine Association

St. Joseph's Healthcare
L-424, St. Luke's Wing
Hamilton, Ontario

Assistant: Rita Taraschi ext.36021

Currently accepting HRM Graduate Students

Marek Smieja

Faculty Biography

Education and Professional Standing

  • PhD Clinical Health Sciences (Health Research Methodology), McMaster University, 2002
  • FRCPC Medical Microbiology and Infectious Diseases, McMaster University, 1998
  • MSc Clinical Health Sciences (Health Research Methodology), McMaster University, 1997
  • MD, University of Western Ontario, 1987


Research Focus

My primary research interests are in the diagnosis of respiratory and gastrointestinal infectionss, and in the role of chronic infections in respiratory and cardiovascular disease.

I am involved in the development and evaluation of respiratory diagnostic tests for SARS-Coronavirus, influenza, and rhinovirus.  Our lab develops tests for respiratory and gastrointestinal infections, in Canada and in Botswana. 

My HIV studies have examined the interaction with HIV infection and cardiovascular disease, with current studies focusing on smoking cessation, inflammation, and dental health.

Clinical Focus

My clinical focus encompasses infectious disease and HIV care.

Academic Interests

I currently teach in the post-graduate Residency Program in Microbiology and Infectious Diseases. I also teach graduate students in Health Research Methodology and Supervision.

Team Members

Research Team

Kathy Luinstra
Sue Carruthers

Graduate Students

Emma Goodall (PhD)

Selected Publications

  • Odueyungbo A, Smieja M, Thabane L, Smaill F, Gough K, Gill J, Anderson T, Elston D, Smith S, Beyene J, Lonn E.  Comparison of brachial and carotid artery ultrasound for assessing extent of subclinical atherosclerosis in HIV: a prospective cohort study. AIDS Res. Ther. 2009 Jun 11; 6:11.
  • Mahony JB, Hatchette T, Ojkic D, Drews SJ, Gubbay J, Low DE, Petric M, Tang P, Chong S, Luinstra K, Petrich A, Smieja M.  Multiplex PCR tests sentinel the appearance of pandemic influenza viruses including H1N1 swine influenza. J Clin Virol. 2009 Jul; 45(3): 200-2.
  • Lamontagne F, Garant M-P, Carvalho J-C, Lanthier L, Smieja M, Pilon D. Pneumococcal Vaccination and Myocardial Infarct Risk. CMAJ 2008: 179:773-7.
  • Friis-Møller N, Smieja M, Klein D. Antiretroviral Therapy as a Cardiovascular Disease Risk Factor - Fact or Fiction? A review of clinical and surrogate outcome studies. Current Opinion in HIV and AIDS 2008: 3(3):220-225.
  • Currier JS, Lundgren JE, Carr A, Klein D, Sabin CA, Sax PE, Schouten JT, Smieja M for Working Group 2. Epidemiological Evidence for Cardiovascular Disease in HIV-Infected Patients and Relationship to Highly Active Antiretroviral Therapy. Circulation 2008: 118(2):e29-35.
  • Daley P, Castriciano S, Chernesky M, Smieja M. Comparison of Flocked and Rayon Swabs for Collection of Respiratory Epithelial Cells From Uninfected Volunteers and Symptomatic Patients. J Clin Microbiol 2006; 44:2265-7.
  • Smieja M, Gnarpe J, Lonn E, Gnarpe H, Olsson G, Yi Q, Dzavik V, McQueen M, Yusuf S for the HOPE study investigators. Multiple infections and subsequent cardiovascular events in the Heart Outcomes Prevention Evaluation (HOPE) Study. Circulation 2003; 107(2):251-257.
  • Smieja M, Mahony JB, Petrich A, Boman J, Chernesky M. Association of Circulating Chlamydia pneumoniae DNA with Cardiovascular Disease: A Systematic Review. BMC Infectious Diseases: 2002; 2:21.

Book Chapters

  • Loeb M, Smaill FM, Smieja M (editors). Evidence-based Infectious Diseases, Second Edition.  Wiley-Blackwell (BMJ Books), Chichester U.K. 2009.  324 pages. 
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