Larger Text
Smaller TextGurmit Singh
, PhD
Professor, Pathology and Molecular Medicine
Division: Molecular Medicine
Associate Member, Biochemistry and
Biomedical Sciences
Senior Scientist, Cancer Care Ontario
Juravinski Cancer Centre
Hamilton, Ontario
905-387-9711 ext. 67004
gurmit.singh@jcc.hhsc.ca
Assistant: Sharon Ralph
Currently accepting Graduate Students
Currently accepting Post Doctoral Fellows
Faculty Biography
Education and Professional Standing
- PhD Pharmacology, Dalhousie University, 1982
- BSc Biochemistry, Dalhousie University, 1977
Interests
General
- Experimental Cancer Therapy for breast and prostate cancer
Specific
- Mitochondria as a target for cancer chemotherapy
- Strategies to modulate bone metastasis
- Molecular and cellular mechanisms of photodynamic therapy
Selected Links
- Juravinski Cancer Centre Research
- Department of Biochemistry Profile
- Faculty of Health Sciences Medical Sciences Graduate Program Profile
Team Members
Post-Doctoral Students
Drs. J. Djiometio, M. Kilemade, J. Lemon, Z. Saikali
Students
R. Cowan, D. Hamelinck, S. Hopmans, H. Lin., E. Seidlitz, M. Sharma, R. Sharma
Selected Publications
- Duivenvoorden WC, Vukmirovic-Popovic S, Kalina M, Seidlitz E, Singh G. (2007). Effect of zoledronic acid on the doxycycline-induced decrease in tumour burden in a bone metastasis model of human breast cancer. British Journal of Cancer, 96(10): 1526-1531.
- Wilson, LA., Gemin, A., Espiritu, R., Singh G. (2005) ets-1 is transcriptionally up-regulated by H202 via an antioxidant response element. FASEB J. 19 (14): 2085-7.
- Khalilli, P., Arakelian, A. Chen, G. Singh, G., and Rabbani, S.A. (2005) Effect of Herceptin on the development and progression of skeletal metastases in a xenograft model of human breast cancer. Oncogene. 24 (44): 6657-66.
- Preston, T.J., Woodgett, J.R. and Singh, G. (2003) JNK1 activity modulates cellular growth arrest response to catalase-mediated scavenging of H2O2. Exp. Cell. Res. 285(1):146-58.
- Vukmirovic-Popovic S., Colterjohn N., Lhotak S., Duivenvoorden W.C.M., Orr F.W., Singh G. (2002) Morphological, histomorphometric, and microstructural alterations in human bone metastasis from breast carcinoma. Bone, 31(4):529-535.
- Preston T.J., Singh G. (2001) Scavenging of extracellular H2O2 by catalase inhibits the proliferation of HER-2/Neu-transformed Rat-1 fibroblasts through the induction of a stress response. J Biol Chem, 276(12): 9558-9564.
Books Edited
- 2005. Bone Metastasis: Experimental and Clinical Therapeutics (Cancer Drug Discovery and Development Series) (Invited Editors, Singh G., Rabbani, S.) Humana Press, NJ, USA
