Donglai Ma

, MD

Assistant Professor
Pathology and Molecular Medicine

St. Joseph's Healthcare
Autoimmunity Research Lab
3rd Floor, Luke Wing Room L305-4
madon@mcmaster.ca

Euroimmun Medical Diagnostics Canada
36 - 1100 Central Parkway West
Mississauga ON L5C 4E5
905-896-1504 ext 202
Fax: 905-896-1506
d.ma@euroimmun.ca

Assistant: Allison Rodriguez (905-896-1504 ext 200)

Education and Professional Standing

• MD, Medical School, Henan University of Sciences & Technologies, China, 1983

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Interests

Research & Clinical Focus

• Autoantibodies & their pathogenesis in autoimmune diseases
• Therapeutic effect of immunomodulators in autoimmune diseases.
• Lupus mouse model
• Standardization of autoantibody testing

Academic Interests

Continuing Education: Autoantibody Diagnostics

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Team Members

Research Assistant

Yufang Wang

Post Doctoral Fellow

Hui Zhao

Selected Publications

• Ma D, Youinou P, D’Costa M, Moss M (Eds). Autoantibodies and their Clinical Significance, Autoantibody Network, Pulsus Publication, in press (2010)
• Ma D, D’Costa M, Carbone Y, et al. Ongoing ANCA Standardization from a Canadian ANCA Work Group. APMIS 2009, Sup 117 (sup 127): 175
• Guha AK, Murray SK, Ma D. Anti-Neucleosome Antibody (ANuA) ELISA from EUROIMMUN: Correlation with Anti-Nuclear Antibody (ANA), Anti-dsDNA and Anti-Sm antibody, Am J Clin Pathol 2004, 121:1
• Furuno T, Ma D, van der Kleij H, Nakanishi M and Bienenstock J. Bone marrow-derived mast cells in mice respond in co-culture to scorpion venom activation of superior cervical ganglion neurites according to level of expression of NK1 receptors, Neuroscience Letters 2004, 372    (3):185
• Ma D, Forsythe P, and Bienenstock J. Live Lactobacillus reuteri Is Essential for the Inhibitory Effect on Tumor Necrosis Factor Alpha-Induced Interleukin-8 Expression, Infection and Immunity 2004, 72 (9): 5308
• van der Kleij H, Ma D, Redegeld FAM, Kraneveld AD, Nijkamp FP and Bienenstock J. Functional Expression of Neurokinin 1 Receptors on Mast Cells Induced by IL-4 and SCF, J Immunol 2003, 171(4):2074
• Ma D, Wolvers D, Stanisz AM, and Bienenstock J. Interleukin-10 and Nerve Growth Factor Have Reciprocal Upregulatory Effects on Intestinal Epithelial Cells, Am J Physiol Regul Integr Comp Physiol 2003, 284(5):R1323
• Wang Y, Ma D, Bienenstock J, et al. Lactobacillus sp. Diminishes T cell-induced mucosal damage in mice in association with an increase in tissue IL-10 mRNA, Mucosal Immunol Update 2002, 10(2&3):2906
• Ma D, Zhang S and Stocker W (Eds). Autoantibodies and Their Immunofluorescent Patterns, Peking Science & Technology Press 2000