Education and Professional Standing
FRCPC, Hematology, McMaster University, 1993
FRCPC, Internal Medicine, University of Toronto, 1991
MD, McMaster University, 1988
Bone Marrow Transplantation and Cell-based Vaccines
Gene Therapy at the Hamilton Health Sciences Corporation, Henderson Site, has been developed in collaboration with the Hamilton Regional Cancer Centre. The emphasis is on Human Clinical Trials in Cancer Therapy and Genetic Immunization. This work is based on preclinical studies completed in laboratories at McMaster University and the Hamilton Health Sciences Corporation.
We have initiated several cancer vaccine studies in patients with metastatic melanoma, chronic lymphocytic leukemia and most recently metastatic breast cancer. Facilities include a Stem Cell Processing Laboratory where stem cells are harvested, purified and subsequently used for cellular vaccination. Adenoviral-based gene transfer is used as a platform to genetically modify autologous antigen presenting cells in patients with melanoma, breast cancer and lymphocytic leukemia.
These studies involve the collaborative efforts of hospital, clinical trials nursing and laboratory staff where flow cytometry, PCR analysis, blood banking and stem cell processing with cryopreservation are all completed.
Based on successful pilot studies, future trials will include collaboration with other centers in Canada.
Dr. Foley’s clinical focus encompasses the following:
- Consultative hematology
- Autologous bone marrow transplant
- Therapeutic plasma exchange
- Director of clinical stem cell laboratory
- Flow cytometry and bone marrow analysis
Dr. Foley’s academic involvement includes:
- Clinical hematology teaching of residents and fellows
- MF4 clinical skills preceptor, McMaster MD Program
- Session Lecturer in Advanced Immunology, HTH SCI 4II3
- Session Lecturer in Human Gene Therapy, MS703
Research Assistant/Coordinator: Elizabeth Scheid
Clinical Trials Nurse Coordinator: Brenda Kowaleski
Technical Specialist, Stem Cell Laboratory: Pamela O'Hoski
Terry Fox Basic Science Research Fellowship
Recipient, Saul Highman Memorial Award, Leukemia Research Foundation of Canada