Education and Professional Standing
- PDF– 2009-2015. McMaster University, Hamilton, ON, Canada. Department of Pathology and Molecular Medicine, McMaster Immunology Research Center, Cancer cell death and immunotherapy
- PhD - 2006-2009. University of Prince Edward Island, PEI, Canada. Department of Pathology and Microbiology, Atlantic Veterinary College. Immunology.
- MSc - 2002-2004. University of Tromso, Norway. Department of Marine Biotechnology,– August. 10, 2004- June 01, 2006
- DVM – 1996-2002. Addis Ababa University, Ethiopia. Faculty of Veterinary Medicine
The ability of the immune system to fight cancer has provided the opportunity to utilize cancer immunotherapy for treating expanding list of cancer types. Various immunotherapies have been shown to provide durable responses in a small fraction of patients. However, many cancer types avoid immune recognition and/or generate adaptive mechanisms to subvert immune attack. Thus my research interests are geared towards understanding and modulating natural and therapy-induced adaptive resistance mechanisms of growing tumors. Particularly, our group is interested to utilize murine tumor models resembling non-T cell-inflamed human tumors, with an overall aim of assessing what immunological interventions can overcome failed spontaneous priming. Currently, we are pursuing the hypothesis that immunogenic cancer cell death can initiate priming in non-T cell infiltrated autochthonous tumors. Our research interests will advance knowledge of cancer immunology as well as generate novel immunotherapeutic strategies to increase the proportion of patients responding to current immunotherapies.