McMaster University

McMaster University

Syed Qadri,

MD, PhD

Assistant Professor (Part-Time)
Pathology and Molecular Medicine

Research Associate, Canadian Blood Services

Faculty of Health Sciences, 3H31

1280 Main Street West
Hamilton, ON L8S 4K1

Email: syed.qadri@mcmaster.ca

Faculty Biography

Education and Professional Standing

  • PDF, Canadian Blood Services and Department of Pathology and Molecular Medicine, McMaster University, Canada, 2015 - 2017
  • PDF, Department of Pharmacology, University of Saskatchewan, Canada, 2012 - 2014
  • Doctoral degree Physiology, Eberhard Karls Universität Tübingen, Germany, 2011
  • Medical degree, Universitatea din Oradea, Romania, 2006

Interests

Academic Interests

 

Medical Foundations and Gross Anatomy for MD Program, Michael G. DeGroote School of Medicine

 

Research Focus

 

Physiology and pathophysiology of erythrocytes in humans and animals models

Plasma and erythrocyte transfusion

Blood product characteristics


Selected Publications

  • Qadri SM, Eltringham-Smith LJ, Bhakta V, Sheffield WP. Thromboelastometry reveals similar hemostatic properties of purified fibrinogen and a mixture of purified cryoprecipitate protein components. Clin Chem Lab Med (2018) 10.1515/cclm-2017-1136
  • Kempe-Teufel DS, Bissinger R, Qadri SM, Wagner R, Peter A, Lang F. Cellular markers of eryptosis are altered in type 2 diabetes. Clin Chem Lab Med (2018) 10.1515/cclm-2017-1058
  • Qadri SM, Donkor DA, Nazy I, Branch DR, Sheffield WP. Bacterial neuraminidase-mediated erythrocyte desialylation provokes cell surface aminophospholipid exposure. Eur J Haematol (2018) 10.1111/ejh.13047
  • Qadri SM, Bissinger R, Solh Z, Oldenborg PA. Eryptosis in health and disease: A paradigm shift towards understanding the (patho)physiological implications of programmed cell death of erythrocytes. Blood Rev (2017) 31(6):349-361
  • Qadri SM, Chen D, Schubert P, Devine DV, Sheffield WP. Early γ-irradiation and subsequent storage of red cells in SAG-M additive solution potentiate energy imbalance, microvesiculation and susceptibility to stress-induced apoptotic cell death. Vox Sang (2017) 112(5):480-483.
  • Qadri SM, Chen D, Schubert P, Perruzza DL, Bhakta V, Devine DV, Sheffield WP. Pathogen inactivation by riboflavin and ultraviolet light illumination accelerates the red blood cell storage lesion and promotes eryptosis. Transfusion (2017) 57(3):661-673.
  • Qadri SM, Donkor DA, Bhakta V, Eltringham-Smith LJ, Dwivedi DJ, Moore JC, Pepler L, Ivetic N, Nazi I, Fox-Robichaud AE, Liaw PC, Sheffield WP. Phosphatidylserine externalization and procoagulant activation of erythrocytes induced by Pseudomonas aeruginosa virulence factor pyocyanin. J Cell Mol Med (2016) 20(4):710-20.
  • Bissinger R, Lang E, Ghashghaeinia M, Singh Y, Zelenak C, Fehrenbacher B, Honisch S, Chen H, Fakhri H, Umbach AT, Liu G, Rexhepaj R, Liu G, Schaller M, Mack AF, Lupescu A, Birnbaumer L, Lang F, Qadri SM. Blunted apoptosis of erythrocytes in mice deficient in the heterotrimeric G-protein subunit Gαi2. Sci Rep (2016) 6:30925.
  • Lang E, Zelenak C, Eberhard M, Bissinger R, Rotte A, Ghashghaeinia M, Lupescu A, Lang F, Qadri SM. Impact of cyclin-dependent kinase CDK4 inhibition on eryptosis. Cell Physiol Biochem (2015) 37(3):1178-86.
  • Lang E, Gatidis S, Freise NF, Bock H, Kubitz R, Lauermann C, Orth HM, Klindt C, Schuier M, Keitel V, Reich M, Liu G, Schmidt S, Xu HC, Qadri SM, Herebian D, Pandyra AA, Mayatepek E, Gulbins E, Lang F, Häussinger D, Lang KS, Föller M, Lang PA. Conjugated bilirubin triggers anemia by inducing erythrocyte death. Hepatology (2015) 61(1):275-84.
  • Lang E, Bissinger R, Fajol A, Salker MS, Singh Y, Zelenak C, Ghashghaeinia M, Gu S, Jilani K, Lupescu A, Reyskens KM, Ackermann TF, Föller M, Schleicher E, Sheffield WP, Arthur JS, Lang F, Qadri SM. Accelerated apoptotic death and in vivo turnover of erythrocytes in mice lacking functional mitogen- and stress-activated kinase MSK1/2. Sci Rep (2015) 5:17316.
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