McMaster University

McMaster University

News Archive

Fall 2014

SUPP and EXPRESSO Trials

We are excited to announce that both SUPP (Glycerin Suppositories Used Prophylactically in Premature infants: a pilot randomized placebo-controlled trial) and EXPRESSO (Expertise-Based Randomize Controlled Trial of Scrotal Versus Inguinal Orchidopexy on Postoperative Pain) are scheduled to begin recruitment January 6, 2015!


Evidence-based Medicine Workshop for Surgical Fellows

Dr. Helene Flageole hosted a workshop on Evidence-based Medicine for surgical fellows at McMaster University from June 12 to June 13th 2014. Eleven participants included students from McMaster Children's Hospital, Western University, and visiting scholars from Nigeria and Uganda. The workshop was a great success, thank you to all who presented and attended!

Bethune Round Table 2014

BRT 2014 McMaster

The 14th Bethune Round Table conference was hosted at McMastser and chaired by Dr. Brian Cameron. The conference attracted 150 participants from 17 countries representing 49 organizations including universities, professional societies and NGOs. The conference theme “Improving Global Outcomes Through Safer Surgery” was addressed by 5 keynote speakers, 27 podium presentations and 21 poster presentations. The high quality of the presentations, the rich discussion and opportunities for networking, and the friendships nurtured will support the ongoing collaborations of Canadian surgeons, anesthetists and obstetricians with colleagues working to improve surgical care in low-resource settings. Post-conference courses were fully subscribed, including the CNIS Trauma Team Training Instructor Course, Regional Blocks for Trauma course, and a Getting Started in Health Research course. The BRT will be held in Calgary in 2015, and Halifax in 2016.

 

Spring 2014

Consortium of Universities for Global Health

MPSRC Intern Claudia Frankfurter recently presented her poster entitled “Understanding the Burden of Surgical Congenital Anomalies in Kenya: An International Mixed-Methods Study” at the fifth annual Consortium of Universities for Global Health in Washington, DC on May 10, 2014.  The conference, themed Universities 2.0- Advancing the Global Health Agenda in the Post-MDG Era, showcased leading scientific advances addressing the complex global health challenges of today. The project was a sub-study of the DAPS study led by Dr. Brian Cameron and Dr. Dan Poenaru.

[The poster can be viewed here]

Julia Pemberton and Claudia Frankfurter at CUGH 2014

 

MPSRC Success at the 2014 CAPS Annual Meeting

The MPSRC has had 6 presentations accepted for the 2014 Canadian Association of Pediatric Surgeons (CAPS) Annual Meeting. As well, congratulations are in order for Dr. Mike Livingston, who won Best Presentation for "Fundoplication versus Gastrojejunostomy for Gastroesophageal Reflux in Children with Neurologic Impairment: A Systematic Review and Meta-analysis." Thank you everyone for your hard work!

Podium:

  • Flageole H, Kanters DM, Pemberton J. Post-Operative Impact of Nasogastric Tubes on Length of Stay in Infants with Pyloric Stenosis (POINTS): A Randomized Controlled Trial. Canadian Association of Pediatric Surgeons. Montreal Quebec, September 18-20, 2014.
  • Livingston MH, Shawyer AC, Rosenbaum P, Jones SA, Walton MJ. Fundoplication versus Percutaneous Gastrojejunostomy for Gastroesophageal Reflux in Children with Neurologic Impairment: A Systematic Review and Meta-analysis. Canadian Association of Pediatric Surgeons. Montreal Quebec, September 18-20, 2014.

Poster:

  • Pond J, Tofighi T, Pemberton J, Walton JM. In-Briefs: A Novel Patient Resource for Pediatric Surgery Nurse Practitioners. Canadian Association of Pediatric Surgeons. Montreal Quebec, September 18-20, 2014.
  • Poenaru D, Pemberton J, Frankfurter C, Cameron BH. The Burden of Waiting: DALYS accrued from delayed access to pediatric surgery in Kenya and Canada. Canadian Association of Pediatric Surgeons. Montreal Quebec, September 18-20, 2014.
  • Livingston M, DCruz J, Pemberton J, Ozgediz D, Poenaru D. Mortality rates associated with pediatric surgical conditions in low and middle-income countries in Africa: a call to action. Canadian Association of Pediatric Surgeons. Montreal Quebec, September 18-20, 2014.
  • Shawyer AC, Hatchell AC, Pemberton J, Flageole H. Compliance with published guidelines for antibiotic use in the post-operative management of children with appendicitis. Canadian Association of Pediatric Surgeons. Montreal Quebec, September 18-20, 2014.

 

Bladder Training for Kids Video Premiere

The "Bladder Training for Kids" animated video was introduced during a recent wine and cheese event on May 1st 2014. The video was created by Dr. Luis Braga and the Pediatric Urology Team at McMaster Children's Hospital for a pilot study comparing the effectiveness of this bladder training video versus standard individual urotherapy for children with bladder dysfunction. This study is funded by the CUA Scholarship Foundation Pfizer Incontinence Fellowship.

Dr. Jorge DeMaria, Mandy Rickard, Natasha Brownrigg, and Dr. Luis Braga at the Bladder Training for Kids Premiere
From left: Dr. Jorge DeMaria, Mandy Rickard, Natasha Brownrigg, and Dr. Luis Braga at the Bladder Training for Kids Premiere

CUA Astellas Scholarship Award

Dr. Luis Braga has just been awarded CUA Astellas Scholarship for his project entitled, “Continuous Antibiotic Prophylaxis versus Placebo in infants diagnosed with Primary Megaureter: A prospective, randomized controlled trial” This $50,000 in funding will allow for external sites to be recruited for this trial that is initially funded by the recent MSA competition.

MSA Clinical Research Awards

Dr. Mark Walton and Dr. Luis Braga have been successful in this year's applications for McMaster Surgical Associates Clinical Research Awards. Despite the competition for these grants, the following two randomized controlled trials have received full funding:

Walton JM, Livingston M, Zequiera J, Pemberton J, Williams C. Do glycerin suppositories decrease the time to full enteral feeds in premature infants? A pilot study for a multicenter randomized placebo-controlled trial. McMaster Surgical Associates Clinical Research Competition. July 1, 2014-June 30-2015. $30,000.

Braga LHP, Pemberton J, Farrokhyar F, Lorenzo A. Expertise−Based Randomized Controlled Trial of Scrotal Versus Inguinal (Standard) Orchidopexy on Postoperative Pain: EXPRESSO Trial. McMaster Surgical Associates Clinical Research Competition. July 1, 2014-June 30-2015. $30,000.

Neonatal Circumcision Article Rated #2 by the CUAJ for 2013

Dr. Jorge DeMaria's article "Are physicians performing neonatal circumcisions well trained?, appeared in the August 2013 issue of the Canadian Urological Association Journal (CUAJ). This article has been ranked #2 on the list of top ten CUAJ articles based on views in 2013.

The article reports on the Neonatal Circumcision Educational workshop he and Dr. Braga hosted in 2010. As a result of the workshop, Dr. DeMaria created an educational video for trained medical professionals conducting neonatal circumcision in the community setting, which can be found on our website.

 

Julia Pemberton Receives President's Award for Outstanding Service

The President's Award is the highest honour McMaster can bestow on any non-teaching employee. Julia Pemberton is the recipient of this award for her outstanding contribution in the past 5 years as the clinical research coordinator for the McMaster Pediatric Surgery Research Collaborative. Julia has acted as a mentor for many young researchers, and introduced the intern mentorship program to the MPSRC. Julia has been an irreplaceable contributor to the MPSRC's success as a globally recognized research leader.

Full biographies of the award recipients can be found here as well as coverage on the ceremony on May 27th:

[View McMaster unviersity President's Awards]

MPSRC Staff Changes

Jessie Heaman

Congratulations to Jessie Heaman

Jessie has been accepted to the University of Guelph to begin her graduate studies in clinical psychology. Jessie has been a research assistant with Dr. Luis Braga and Dr. Jorge DeMaria in the Division of Pediatric Urology since 2012, and has been instrumental in conducting the ALPHA Trial.

The MPSRC would like to thank Jessie for her hard work and dedication to the MPSRC. Our sincerest congratulations to Jessie for this next important step in her research career.

Congratulations to David Kanters

David has been accepted to the Health Research Methodology (HRM) David KantersGraduate Program at
McMaster University in September 2014 and will be studying under the supervision of Dr. Luis Braga. In order to take on this new role, David will be completing his work with the MPSRC in June. David has been involved in numerous projects in Pediatric Urology and Pediatric Surgery including the Hypospadias Outcomes Long-term Database, the CIHR International Pediatric Urology Task Force on Hypospadias, and the POINTS trial.

Congratulations to Claudia Frankfurter

MPSRC intern Claudia Frankfurter has been accepted to the University of Toronto medical school starting in September 2014. Our sincere thanks to Claudia for all of her hard work in the MPSRC for the past three years.

Congratulations to Michael Gallea

Michael has accepted a position at the University of British Columbia Medical School. Michael was an intern at the MPSRC from 2011-2012, working on the CARE Study under the supervision of Dr. Mark Walton. Congratulations to Michael on his success!

Jennifer D'Cruz

Welcome Jennifer D'Cruz

We would also like to welcome Jennifer D'Cruz to the MPSRC, who will be taking on the position of research assistant in pediatric urology. Jennifer has completed her Bachelor of Health Science at McMaster and is currently studying for her Master's degree in Health Research Methodology.

Thank-you 2013-2014 MPSRC Interns

The 2013-2014 MPSRC Internship program has completed another successful year. The MPSRC would like to extend thanks to all of the talented and hard-working individuals who help with our research through their hard work in volunteer placements and thesis projects.

 

HHS Foundation Gala

HHS Gala: For Your Eyes Only

The Hamilton Health Sciences Foundation Annual Fundraising Gala was held at the Hamilton Convention Centre on March 29, 2014 . This year's James Bond inspired event, For Your Eyes Only, featured a performance by Grammy-award winning artist Sheena Easton. The Gala was a resounding success, raising more than $600,000 for healthcare research in Hamilton! Over 900 people were in attendance.

MPSRC at the 2014 HHS Gala: (left to right) Dr. Luis Braga, Dr. Jorge DeMaria, Julia Pemberton, Dr. Helene Flageole, Dr. Karen Bailey, Dr. Mark Walton

MPSRC at the 2014 HHS Gala: (left to right) Dr. Luis Braga, Dr. Jorge DeMaria, Julia Pemberton, Dr. Helene Flageole, Dr. Karen Bailey, Dr. Mark Walton

The HHS Foundation only chooses 5 research programs each year to fund, and the MPSRC was chosen to represent McMaster Children's Hospital. Three of our projects were highlighted at the gala including Dr. Braga’s ALPHA trial, Dr. Cameron’s international DAPS study, and Dr. Sabri’s national SCREEN-ROP study. To learn more about the HHS Gala and other projects that are being funded, please visit the 2014 HHS Gala website.

Pediatric Urology Research Accepted at CUA 2014

Dr. Luis Braga, Dr. Jorge DeMaria, and their research team have had six presentations accepted at the 2014 Canadian Urological Association Annual Meeting. Dr. Braga will be presenting "Time to Febrile Urinary Tract Infection (fUTI) in Children with Antenatal Hydronephrosis (AHN): a Prospective study" as one of the six podium presentations during the conference. Other presentations accepted as moderated posters were a prospective study on preoperative hormone stimulation in hypospadias patients, an economic evaluation of antibiotic treatment in antenatal hydronephrosis patients, an RCT studying urotherapy, a prospective study on gubernaculum-sparing laparoscopic orchidopexy, and a case report video showing novel surgical technique for massively-enlarged polycystic kidneys in a child. The full citations are available in the Scholarship section.

  • Braga LH, Kanters DM, Farrokhyar F, Pemberton J, Lorenzo A. Time to Febrile Urinary Tract Infection (fUTI) in Children with Antenatal Hydronephrosis (AHN): a Prospective study. 69th Annual Meeting of the Canadian Urological Association. St. John's Newfoundland. 2014-6-30.
  • Braga LH, Pemberton J. Can More Cost Less? An Economic Evaluation of Prophylactic Antibiotic Treatment for Infants with High Grade Hydronephrosis for the Prevention of Urinary Tract Infections in Canada. 69th Annual Meeting of the Canadian Urological Association. St. John's Newfoundland. 2014-6-30.
  • Braga LH, Kanters DM, Pemberton J, DeMaria J, Bagli D, Lorenzo A. Effect of Preoperative Hormone Stimulation (PHS) on Hypospadias Severity and Urethrocutaneous Fistula (UCF) Rate after Tubularized Incised Plate (TIP) Repair: A Prospective Analysis. 69th Annual Meeting of the Canadian Urological Association. St. John's Newfoundland. 2014-6-30.
  • Brownrigg N, Pemberton J, Heaman J, Jegatheeswaran K, DeMaria J, Braga LH. More is Not Necessarily Better: A randomized controlled trial evaluating the effectiveness of group versus individual urotherapy in reducing symptoms associated with bladder dysfunction. 69th Annual Meeting of the Canadian Urological Association. St. John's Newfoundland. 2014-6-30.
  • Braga LH, Lorenzo A, DeMaria J. Laparoscopic Orchidopexy With or Without Preservation of Cremasteric Vessels: Can We Reduce Atrophy Rates? 69th Annual Meeting of the Canadian Urological Association. St. John's Newfoundland. 2014-6-30.
  • Bansal R, Lorenzo A, DeMaria J, Kanters DM, Braga LH. Laparoscopic Renal Cyst Decortication (LRCD) for Autosomal Dominant Polycystic Kidney Disease (ADPKD) in a 5-year-old Child. 69th Annual Meeting of the Canadian Urological Association. St. John's Newfoundland. 2014-6-30.

Circumcision Website Featured in Medical Post

The Medical Post has published an article featuring Dr. Jorge DeMaria and the neonatal circumcision education website he created to inform community practitioners performing this procedure. The article, "Training videos review techniques, contraindications, and complications" was written by Gillian Wainsbrough for the November 2013 edition of the Medical Post online publication, CanadianHealthcareNetwork.ca. Subscribers can view the full Medical Post article on Dr. DeMaria's website through the link provided. The Neonatal Circumcision Education website can be found here.

Bethune Round Table 2014

The 2014 Bethune Round Table Conference on International Surgery will be hosted at McMaster University on June 5-8, 2014.

The DAPS study will be presented at the podium during the conference. MPSRC Intern Claudia Frankfurter will also be giving a poster presentation on the disability associated with congenital anomalies, part of the DAPS study, at this year's 5th Annual Consortium of Universities for Global Health (CUGH) in Washington, DC. The DAPS study is conducted by Dr. Brian Cameron, Dr. Dan Poenaru, and Julia Pemberton, with the help of Claudia.

Dr. Mike Livingston will also be presenting a scoping review of pediatric surgery outcomes in low- and middle-income African countries, a project completed with MPSRC interns Allyson Shorkey and Jennifer D'Cruz and supervised by Dr. Dan Poenaru.

 

Winter 2014

MPSRC Student Research Day 2014

The 2nd Annual MPSRC Student Research Day was held on January 29th, 2014. This is an opportunity for MPSRC interns to present their projects in an academic setting that gives the experience of a conference podium presentation. This year's winner of First Prize is Stephanie Noronha, for her presentation on, "Evaluating Factors Affecting Medication Compliance in a Randomized Controlled Trial in Pediatric Urology: The Effect of Baseline Parameters". Thank you to the MPSRC members who attended and provided valuable feedback to our students. Follow the link to view the program of presentations.

New Study Coordinator for SCREEN-ROP

Our study team is ever revolving and here we would like to acknowledge our past and present members! The study team would like to thank Kaitlyn Whelan for helping set up and  initiate the SCREEN ROP study, as well we thank Virginia Viscardi for all her work coordinating the SCREEN ROP study. We wish them all the very best in their future endeavours and career. We would also like to welcome Sahira Husain, who has now taken over the role of the SCREEN-ROP study coordinator. Please direct all enquiries regarding the study to Ms. Husain via  email: shusain@mcmaster.ca or telephone: 905 521 2100 extension 73510.

New Publication Accepted to JPS

The MPSRC's recent submission, "Post-operative management of esophageal atresia-tracheoesophageal fistula and gastroesophageal reflux: A Canadian Association of Pediatric Surgeons Survey", has been accepted for publication by the Journal of Pediatric Surgery. Congratulations to everyone involved, the full citation is below.

  • Shawyer A, Pemberton J, Flageole H. Post-operative Management of Esophageal Atresia-Tracheoesophageal Fistula and Gastroesophageal Reflux: A Canadian Association of Pediatric Surgeons Survey. Journal of Pediatric Surgery. (Accepted)

Research in Urology Accepted for Presentation 2014 SPU Annual Meeting

Dr. Luis Braga and Natasha Brownrigg have each had abstracts accepted for presentation at the Society for Pediatric Urology section of the American Urological Association Annual Meeting, on May 16-17, 2014 at the Rosen Centre Hotel in Orlando, Florida. Dr. Braga will present on results from his prospective study on time to febrile UTI in children with antenatal hydronephrosis and Natasha will present on the Urotherapy randomized controlled trial. Congratulations to everyone involved. The full citations are below.

  • Braga LH, Kanters DM, Farrokhyar F, Pemberton J, Lorenzo AJ. Time to Febrile Urinary Tract Infection (fUTI) in Children with Antenatal Hydronephrosis (AHN): a Prospective study. American Urological Association 2014 Annual meeting. Orlando, Florida. 2014-5-17.
  • Brownrigg N, Pemberton J, Heaman J, Jegatheeswaran K, DeMaria J, Braga LH. More is Not Necessarily Better: A randomized controlled trial evaluating the effectiveness of group versus individual urotherapy in reducing symptoms associated with bladder dysfunction. American Urological Association 2014 Annual meeting. Orlando, Florida. 2014-5-17.

Presentation Accepted at ESPU 2014

Dr. Luis Braga's study on Ultrasound for Diagnosis of Undescended Testis has been accepted for an extended podium presentation at the European Society for Pediatric Urology (ESPU) 2014 Annual Meeting in Austria. This year's conference was highly competitive, as only 35% of the abstracts submitted were accepted for presentation. The full citation is below.

  • Braga LH, Brownrigg N, Farrokhyar F, Pemberton J, Kanters DM, Bansal R, DeMaria J. Ultrasound for Diagnosis of Undescended Testis: Is it Better to Just Flip a Coin? European Society for Pediatric Urology 2014 Annual Meeting. Innsbruck, Austria. 2014-5-18. (Accepted)

 

Fall 2013

New Publications Accepted from Pediatric Urology

Three recent submissions by Dr. Braga and Dr. DeMaria have been accepted to major pediatric urology journals: two to the Journal of Urology and one to Urology. Congratulations to Dr. Braga, Dr. DeMaria and their team. The full citations are below.

  • Braga LH, Ruzhynsky V, Pemberton J, Farrokhyar F, DeMaria J, Lorenzo A. Evaluating Practice Patterns in the Treatment of Antenatal Hydronephrosis: A National Survey of Pediatric Urologists & Nephrologists. Urology. (Accepted)
  • Braga LH, Pemberton J, Heaman J, DeMaria J, Lorenzo A. Pilot Randomized Placebo-Controlled Trial to Investigate the Effect of Antibiotic Prophylaxis on the Rate of Urinary Tract Infection in Infants with Antenatal Hydronephrosis. Journal of Urology. (Accepted)
  • Zareba P, Lorenzo A, Braga LH. Risk Factors for Febrile Urinary Tract Infections (fUTI) in Children with Antenatal Hydronephrosis (AHN): Comprehensive Single Center Analysis of 376 Infants. Journal of Urology. (Accepted)

 

Antenatal Hydronephrosis Systematic Review Featured in Beyond the Abstract in UroToday

Dr. Luis Braga's commentary paper for the article entitled "Antibiotic prophylaxis for urinary tract infections in antenatal hydronephrosis" was published on Tuesday, October 15 as part of Beyond the Abstract. This series is one of the most popular and well-read features on the UroToday website. The paper as is appears on UroToday can be found here.

 

Dr. DeMaria's Neonatal Circumcision Education Article Featured in the National Post, NewsTalk Radio

The National Post released an article featuring Dr. Jorge DeMaria and his recent publication on the training of doctors performing neonatal circumcisions. The full article can be found below.

Dr. DeMaria was interviewed on the "Jim Richards Showgram" on News Talk Radio 1010 Toronto about the National Post Article and concerns that many doctors performing circumcisions may be poorly trained for the procedure. Dr. DeMaria was also interviewed on News Talk Radio 770 in Calgary.

The article by Dr. DeMaria outlines results of the Neonatal Circumcision Educational workshop he and Dr. Braga hosted in 2010, and is published in the August 2013 edition of the Canadian Urological Association Journal.

As a result of the workshop, Dr. DeMaria created an educational video for trained medical professionals conducting neonatal circumcision in the community setting, which can be found on our website.

 

MPSRC Represented at CAPS Annual Meeting

Dr. Karen Bailey, Dr. Helene Flageole and Dr. Anna Shawyer had their work presented at the 2013 Annual Meeting of the Canadian Association of Paediatric Surgeons in Charlottetown, PEI. Congratulations on all of your hard work.

The full citations are below and the meeting program can be found here.

  • Shawyer AC, Pemberton J, Flageole H. Post-operative management of gastroesophageal reflux after esophageal atresia-tracheoesophageal fistula repair: a CAPS survey. Canadian Association of Pediatric Surgeons (CAPS) 45th annual meeting. Charlottetown, PEI. 2013-9-26. (Moderated Poster)
  • Bailey K, Cunningham C, Pemberton J, Morrison K. Understanding Paediatric Surgeons’ Decision Making for the Treatment of Childhood Obesity Across Canada: A Choice-based Conjoint Experiment. Canadian Association of Pediatric Surgeons (CAPS) 45th annual meeting. Charlottetown, PEI. 2013-9-26. (Podium)

CIHR International Pediatric Urology
Task Force on Hypospadias

This meeting was held September 19th, 2013 at the Aria Hotel in Las Vegas, Nevada. Attendees included pediatric urologists from across Canada, the USA, Brazil, and Europe. Dr. Luis Braga hosted the meeting in collaboration with Dr. Darius Bagli, Dr. Armando Lorenzo, and Dr. Joao Pippi Salle from the Hospital for Sick Children.  Support for the meeting was provided by a Planning Grant from the Canadian Institutes of Health Research. The one-day meeting included expert speakers on: prospective data collection in multicentre research, editors from top pediatric urology journals, and a representative of the patient organization Hypospadias and Epispadias Association. The afternoon included sessions for discussion on reporting standards on hypospadias surgery and improving the quality of the literature in this area. The goal of this meeting was to advance hypospadias research toward consensus on reporting standardization and global collaboration.

An evaluation was distributed at the end of the conference to the 33 invited participants, 100% of which were returned. The evaluation revealed that 85% of participants either agreed or strongly agreed (6/7 or 7/7 on a 7-point Likert scale) they were satisfied with the workshop overall, 81% would use the reporting standards discussed, and 91% saw the meeting as a useful opportunity to network and build research capacity. A high majority of the participants (97%) agreed or strongly agreed that the meeting was well-organized and the workshop was well-facilitated. Most participants (82%) agreed or strongly agreed that this meeting will help in conducting multicentre research on hypospadias in the future.

Comments from participants included examples such as: "I have been very grateful to take part in this landmark meeting. I look forward to future collaboration with colleagues and the fruit that it will bear,” and “extremely well done symposium on a very difficult topic with so little evidence base & significant subjectivity & reporting bias.” The most common feedback given in the evaluations was the need for more group discussions and follow-up meetings on this topic.

CIHR International Pediatric Urology Task Force on Hypospadias Sept 19 2013

 

 

 

 

 

 

 

 

 

 

 

 

CIHR International Pediatric Urology Task Force on Hypospadias Sept. 19 2013

 

Society for Pediatric Urology Fall Congress

The Society for Pediatric Urology recently hosted the Pediatric Urology Fall Congress on September 20-22, 2013. Dr. Luis Braga and Julia Pemberton each gave podium presentations during the meeting and both presentations were nominated as Clinical Prize Finalists. The citations are below with links to the full abstracts.

Pemberton J, Lorenzo A, Braga LH. Cost Analysis of Prophylactic Antibiotics versus Placebo to Prevent Urinary Tract Infections in Infants with High Grade Hydronephrosis. SPU Pediatric Urology Fall Congress, Sept. 21, 2013.

Braga LH, Farrokhyar F, Lorenzo A. Prospective Single Center Analysis on the Diagnostic Performance of Measurements of the Normally Descended Gonad in Predicting Monorchidism in Boys with Unilateral Non-palpable Testis. SPU Pediatric Urology Fall Congress, Sept. 21, 2013.

 

Dr. Luis Braga Appointed Director of the McMaster Pediatric Surgery Research Collaborative

Dr. Braga with Research Staff Jessie Heaman

Dr. Luis Braga (pictured above, left) has been an invested member of the MPSRC since its conception, raising the bar for clinical research with his ground breaking studies on treatment of antenatal hydronephrosis and long-term outcomes of hypospadias surgery. This innovative work, in addition to running Industry-sponsored clinical trials and prospective studies on undescended testis and lower urinary tract dysfunction, continues to solidify Dr. Braga’s status as a top researcher in pediatric urology.

During his time with McMaster Dr. Braga has authored over 70 peer-reviewed publications and received $400,000 in peer-reviewed grant funding from many organizations including PSI, CIHR, and the Department of Surgery.

After great success within the Division of Urology, Dr. Braga aims to lead the MPSRC to further develop ties both within the McMaster Community and internationally, and dedicate his time to achieving a plan for sustainable growth within the Collaborative.

Please join us in congratulating Dr. Braga on his role as the
new MPSRC Director!

 

Summer 2013

Canadian Urological Association (CUA) 2013 Annual Meeting

The MPSRC was well-represented at this year's CUA annual meeting. Ten moderated posters were presented from the work of Dr. Luis Braga and Dr. Jorge DeMaria in the Division of Urology. Research staff Jessie Heaman and David Kanters each gave a presentation, while Dr. Braga presented five posters at meeting, urology resident Dr. Soojin Kim presented two, and urology Nurse Practitioner Natasha Brownrigg presented one. Dr. DeMaria was invited to be the moderator of the session.

The Posters presented at the 2013 CUA can be viewed here.

Dr. Bailey's Article Featured on MDLinx.com

Dr. Karen Bailey's published article, Understanding academic clinicians varying attitudes toward the treatment of childhood obesity in Canada: A descriptive qualitative approach, was summarized on the website MDLinx.com. Click here for a link the review of Dr. Bailey's article.

Pediatric Urology Fall Congress

Dr. Luis Braga and Julia Pemberton have each had a podium presentation accepted at the Society for Pediatric Urology (SPU) Fall Congress Meeting. Julia will give a podium presentation on her "Cost Analysis of Prophylactic Antibiotics vs. Placebo to Prevent Urinary Tract Infections in Infants with High Grade Hydronephrosis. Dr. Braga will also be giving a podium presentation on his study examining the performance of diagnostic measurements of the normally descended gonad in predicting monorchidism in patients with unilateral non-palpable testis. Dr. Braga's Pediatric Urology Task Force on Hypospadias will also take place during the SPU Fall Congress.

Canadian Association of Paediatric Surgeons (CAPS) Annual Meeting

Dr. Karen Bailey and Dr. Anna Shawyer will each be giving a podium presentation at the 2013 annual CAPS meeting this September in Charlottetown, Prince Edward Island. Dr. Bailey will present on "Understanding Paediatric Surgeons’ Decision Making for the Treatment of Childhood Obesity Across Canada: A Choice-based Conjoint Experiment", and Dr. Shawyer her findings from a survey of CAPS members in 2012 entitled, "Post-operative management of gastroesophageal reflux after esophageal atresia-tracheoesophageal fistula repair: a CAPS survey"

Global Health Metrics and Evaluation Conference (GHME)

Dr. Poenaru and Dr. Cameron's abstract from our DAPS project was presented at the recent GHME conference. This is the first time the MPSRC will be presenting at this global health research meeting. The DAPS study was generously funded by the McMaster Surgical Associates.

Dr. Poenaru GHME 2013
Dr. Poenaru presenting on the DAPS study at the 2013 GHME Conference

The abstract for this presentation was published in a special issue of the prestigious journal, The Lancet, containing abstracts from 48 countries presented at the third Global Health Metrics and Evaluation Conference.

Poenaru D, Pemberton J, Frankfurter C, Cameron BH. Establishing Disability Weights for Congenital Pediatric Surgical Disease: A cross-sectional, multi-modal study. The Lancet, Volume 381, Page S115. 17 June 2013.

Lancet Website (GHME Conference Publication from DAPS study)

CUA-Pfizer Grant Awarded

Dr. Rahul Bansal, a transplant fellow in the Division of Urology, and Dr. Luis Braga were awarded funding in the amount of $60,000 from the CUA-Pfizer Incontinence Fellowship for their Bladder Training Video Pilot Study. This trial will involve the creation of a bladder training video and evaluate the preliminary effectiveness of video instruction to teach urotherapy to patients with non-neurogenic lower urinary tract dysfunction.

MPSRC Summer Staff

We are proud to welcome three new members to our team for the summer of 2013!

Claudia Frankfurter has been involved with the MPSRC for the past two years. Claudia is currently studying for her Bachelor of Health Sciences at McMaster and will be entering her 3rd year in September. Claudia is a returning member of the 2012 MPSRC summer staff and will be working primarily on the ActNow study with Dr. Bailey.

Alessandro Caroti was an intern with the MPSRC during the 2012-2013 school year. He has recently completed his degree in the Bachelor of Health Sciences program at McMaster. Alessandro has been involved with the bowel anastomosis training module project with Dr. Cameron and will be starting a systematic review with Dr. Braga.

Kizanee Jegatheeswaran also returns from the MPSRC 2012-2013 Internship Program and will continue to work on the ALPHA trial under Dr. Braga, in addition to taking on a role with the Urotherapy trial. Kizanee will be entering her 3rd year of study in the Bachelor of Health Sciences program at McMaster this coming fall.

Brian Maguire is fourth year Mathematics and Statistics Co-op student at McMaster University. Bryan will be completing a co-op placement this summer with Dr. Sabri in pediatric ophthalmology and will be primarily in charge of data collection, cleaning and analysis for the SCREEN-ROP study.

 

McMaster Surgical Associates Grants Awarded

The Dr. Braga, Dr. Cameron, and Dr. Flageole have been successful in their recent applications for MSA funding. The full citations are below, congratulations to everyone involved!

  • Cameron B, Pemberton J, Bailey K, Choi M. Bethune Round Table Conference at McMaster. McMaster Surgical Associate Education Grant $15,000.
  • Flageole H, Pemberton J. Becoming an Academic Pediatric Surgeon: A Clinical Health Research Workshop. McMaster Surgical Associate Education Grant $14,960.00.
  • Braga LH, Brownrigg N. Effectiveness of a Bladder Training Video for management of lower urinary tract symptoms in children. McMaster Surgical Associates Clinical Research Grant $ 29,999.27
  • Braga LH. The Effectiveness of Prophylactic Antibiotics in Preventing Urinary Tract Infections in Children with Primary Megaureter. McMaster Surgical Associates Clinical Research Grant $ 29,930.00

Dr. Sabri Awarded PSI Grant

The MPSRC is proud to announce that Dr. Kourosh Sabri was successful in his application to the Physicians' Services Incorporated Foundation. The project that will be funded by the grant is entitled, “Pediatric Eye Disease Video Interpretation and Diagnosis (PED-VID) Study”. The PED-VID Study is a multi-centred, prospective clinical study between McMaster University (Ophthalmology), University of Waterloo (Optometry) and University of Toronto Sick Kids (Ophthalmology) looking at using telemedicine and video interpretation for diagnosing eye disease and ocular signs of neurosurgical emergencies. The study will take approximately 2 years, recruiting nearly 150 children into the study. Dr. Sabri and his team at McMaster are the lead site, and Dr. Sabri is the Principal Investigator. The total funding awarded is in the amount of $110,000.

McMaster BHSc Poster Day

Three MPSRC interns in the McMaster Bachelor of Health Sciences Program, Allyson Shorkey, Jennifer D'Cruz and Alessandro Caroti, presented posters on their thesis projects during their program's BHSc Poster day. Congratulations on a job well done!

MPSRC Interns Allyson Shorkey and Jennifer D'Cruz presenting a poster on their thesis project

 

Dr. Brian Cameron Appears on National News

Dr. Brian Cameron recently appeared in a Global Television article on the dangers of children swallowing strong magnets. Dr. Cameron saved the a small girl's life when magnets she swallowed created holes in her stomach and intestine. The story can be viewed through the link below.

[Global News: Young kids can swallow magnets, seriously damage intestines, doctors warn - News Hour - Videos | Global Toronto]

 

MPSRC Recent Success

Dr. Brian Cameron gave a presentation entitled "Quantification of Global Burden of Pediatric Surgical Disease Using Disability Weights: Implications for Priority Setting." at the 2013 Bethune Round Table Conference, Hosted by the University of British Columbia Branch for International Surgery, on May 10-11 2013 in Vancouver, British Columbia.
Authors: Julia Pemberton, Claudia Frankfurter, Dr. Brian Cameron, and Dr. Dan Poenaru.

Dr. Kourosh Sabri has had several recent accomplishments in his research, including 2 recent publications and 3 upcoming podium presentations.

  • Published in the December 2012 issue of The Canadian Journal of Ophthalmology:
    National variations in retinopathy of prematurity screening criteria in Canada: existent guidelines and actual practice patterns. Canadian Journal of Ophthalmology. 2012 Dec;47(6):473-8
    Authors: Vasudha Gupta, K. Whelan, L. Schneider, F. Farrokhyar, S. Shivananda, S. Lee, K. Sabri
  • Published in the April 2013 issue of the Journal of the American Association of Pediatric Ophthalmology and Strabismus:
    “Choice of Conjunctival Incisions for Horizontal Rectus Muscle Strabismus Surgery in Children and Adults – An International Survey of AAPOS Members”
    Authors: M. Mikhail, R. Verran, F. Farrokhyar, K. Sabri
  • Podium presentation accepted to be presented at the Canadian Ophthalmological Society Conference in June 2013 in Montreal, Quebec. This presentation will be given at both the Canadian Retina Society and the Canadian Pediatric Ophthalmology Society meetings during the conference:
    “Seminal Canadian Recommendations for Evidence Based Examination of Neonates for Retinopathy Of Prematurity (SCREEN-ROP) - Provisional New Guidelines"
    Authors: K. Whelan, V. Viscardi, N. Patel, W. Seidlitz, F. Farrokhyar, S. Shivananda, A. Ells, S. Lee, K. Sabri
  • Podium presentation accepted to be presented at the Canadian Orthoptic Society meeting in June 2013:
    “How to Improve Patching Compliance in Challenging Ambylopic Children? A Case for Elbow Splinting”
    Authors: R. Riyaz, V. Viscardi, V. Mehta, B. Wakeman, K. Sabri

The McMaster Division of Urology has had 10 moderated posters and 2 video presentations accepted to he Canadian Urological Association 2013 Annual Meeting in June 2013 in Niagara Falls, Ontario. These presentations showcase the recent work of Dr. Braga, Dr. DeMaria and their research team.

Moderated Poster Presentations:

  • Risk Factors for Febrile Urinary Tract Infections (fUTI) in Children with Antenatal Hydronephrosis (AHN): Comprehensive Single Center Analysis of 376 Infants.
    Authors: Merrow M, Abdulla A, Pemberton J, Heaman J, Lorenzo A, DeMaria J, Braga LH
  • Improving Parental Involvement In A Randomized Placebo-Controlled Trial In Pediatric Urology: The Effect Of Informative And Easy-To-Use Trial Media.
    Authors: Heaman J, Pemberton J, Jegatheeswaran K, Braga LH
  • Society Of Fetal Urology (SFU) Grading System Compared To Anteroposterior Diameter (APD) Measurement For Monitoring Infants With High Grade Hydronephrosis: Preliminary Analysis From The Alpha Pilot Trial.
    Authors: Braga LH, Heaman J, Pemberton J, DeMaria J on behalf of the ALPHA Steering Committee
  • Introducing The Research Electronic Data Capture System: An Innovative Data Management Tool in Pediatric Urology Clinical Research.
    Authors: Kanters DM, Pemberton J, Braga LH, DeMaria J
  • Hypospadias Outcomes Long-term Database (HOLD): Preliminary Results.
    Authors: Braga LH, DeMaria J, Kanters DM, Pemberton J
  • Feasibility of Conducting a Prospective Randomized Controlled Trial to Evaluate the Effectiveness of Group versus Individual Urotherapy in Children with Bladder Bowel Dysfunction.
    Authors:
    Brownrigg N, Merrow M, DeMaria J, Pemberton J, Heaman J, Braga LH
  • Agreement Between Referring Physicians’ And Pediatric Urologists’ Diagnosis Of Undescended Testis As Compared To The Performance Of Ultrasound As A Diagnostic Test.
    Authors: Braga LH, Brownrigg N, Pemberton J, Kanters DM, DeMaria J
  • Prospective Analysis on the Diagnostic Performance of Measurements of the Normally Descended Gonad In Predicting Monorchidism In Boys With Unilateral Non-Palpable Testis.
    Authors: Braga LH, Kim S
  • Determining Perception of Urology as a Specialty by Canadian Medical Students. 
    Authors: Kim S, Reid S, Braga LH

Video Presentations:

  • Educational Tool For Community Physicians Performing Neonatal Circumcisions Part I: Review Of Local Anesthesia, Contraindications, and Complications.
    Authors:
    DeMaria J, Kanters DM, Pemberton J, Braga LH
  • Educational Tool For Community Physicians Performing Neonatal Circumcisions Part II: Surgical Techniques.
    Authors: DeMaria J, Kanters DM, Pemberton J, Braga LH

 

Spring 2013

Surgeon Scientist Program Lecture by Dr. Luis Braga

Dr. Luis Braga recently presented a lecture for the Surgeon Scientist Program on April 9th, 2013. The McMaster Surgeon Scientist Program (SSP) operates as part of McMaster's pre-established Clinical Investigator Program (CIP), a Royal College accredited postgraduate research training program.

CIHR Planning Grant Awarded

We are excited to announce Dr. Luis Braga’s success with the recent Canadian Institutes of Health Research (CIHR) Planning Grant ($25,000) entitled, “Establishing an International Pediatric Urology Task Force on Hypospadias Repair: Standardizing Surgical Outcomes in Clinical Research.” The MPSRC was also successful in each of it's three previous applications to the CIHR in this category.
Authors: Dr. Luis Braga, Dr. Darius Bagli, Dr. Armando Lorenzo. Dr. Joao Pippi Salle, and Julia Pemberton.

MPSRC Success

Dr. Brian Cameron will be giving a presentation entitled "Quantification of Global Burden of Pediatric Surgical Disease Using Disability Weights: Implications for Priority Setting." at the 2013 Bethune Round Table Conference, Hosted by the University of British Columbia Branch for International Surgery, on May 10-11 2013 in Vancouver, British Columbia.
Authors: Julia Pemberton, Claudia Frankfurter, Dr. Brian Cameron, and Dr. Dan Poenaru.

Dr. Kourosh Sabri has had several recent accomplishments in his research, including 2 recent publications and 3 podium presentations.

The McMaster Division of Urology has had 10 moderated posters and 2 video presentations accepted to he Canadian Urological Ass oca ti on 2013 Annual Meeting in June 2013 in Niagara Falls, Ontario. These presentations showcase the recent work of Dr. Braga, Dr. DeMaria and their research team. The full citations can be viewed in the Scholarship seciton of the website.

Winter 2013

2013 MPSRC
Intern Presentations

MPSRC Interns

The 2013 MPSRC Intern conference was a resounding success. The goal of this meeting was to provide an opportunity for all the interns working with the MPSRC to give presentations on the progress and status of their projects at the halfway point of their internship. The interns' presenations also included challenges they have overcome, lessons they have learned and their future goals. Interns involved in research in Pediatric Surgery, Pediatric Urology, and Pediatric Ophthalmology participated, all of whom gave impressive presentations. Dr. Kourosh Sabri, Dr. Brian Cameron and Dr. Luis Braga all graciously attended the presentations and gave helpful feedback for the students. Thank you to everyone involved for your hard work and congratulations on a job well done!

 

MPSRC Achievements

MPSRC Intern Claudia Frankfurter gave a poster presentation on the DAPS study at the second Brock-McMaster Undergraduate Global Health Forum on January 26th 2013 at Brock University. Click the links below to view the poster and read more about Claudia's presentation in her article on the ISD website.

[DAPS Poster presented at CCGHR]

[DAPS and the Brock-McMaster Global Health Forum]

Four presentations have been accepted at the Trauma 2013 meeting jointly held by the Trauma Association of Canada (TAC) and Australasian Trauma Society (ATS). This multidisciplinary scientific meeting will combine current clinical updates, discussion panels on controversial issues, and original scientific investigations in the field of trauma care. Canada and Australia face common challenges in the care of trauma victims such as diverse geographical barriers and widely spread populations with similar trauma case loads.

Congratulations to Dr. Cameron on his 2 latest publications in the American Journal of Surgery. This is the first time the MPSRC has published in this journal!

The MPSRC will have four new articles published in the May 2013 edition of Journal of Pediatric Surgery. These include and article on the CARE study by Dr. Walton, an article on the ACT NOW study by Dr. Bailey, an article by Dr. Cameron on outcomes following neonatal PDA ligation, and an article by medical student Charles Wong and Dr. Cameron on a survey conducted with the Canadian Neonatal Network.

There will be two podium presentations given by the MPSRC at the Society for Pediatric Urology's 61st Annual Meeting on May 3-5 2013 in San Diego, California. Thse include presentations from the ALPHA and Urotherapy trials led by Dr. Braga and Dr. DeMaria.

The full citations of the above publications can be found in the Scholarship section.

 

Acclaim for Antenatal Hydronephrosis Systematic Review

Infectious Diseases in Children, a publication on Healio.com, has written a featurette on Dr. Braga's recent sytematic review published in Pediatrics.

[The featurette can be read here]

This article has also been recommended as being of special significance in its field by Hsi-Yang Wu from the F1000 Faculty. For subscribers of F1000Prime, a brief written recommendation of the article is available on
the F1000Prime website.

 

ALPHA Published in Pediatrics

The Journal of Pediatrics has published a systematic review by Dr. Luis Braga. This is Dr. Braga's first publication in the prestigious journal.

The full citations is below:

The Journal of Pediatrics has published a systematic review by Dr. Luis Braga. This is Dr. Braga's first publication in the prestigious journal. 2013 Jan;131(1):e251-61. Published online December 17th, 2012.
(link to article in PubMed)

Dr. Braga’s systematic review focuses on the effectiveness of antibiotic prophylaxis (versus placebo or no treatment) in the prevention of urinary tract infections in infants with high grade hydronephrosis. Dr. Braga is also conducting a randomized controlled trial to study this research question. The ALPHA Trial is a multi-center randomized controlled trial and is funded by the PSI Foundation. For more information on the ALPHA Study, please visit the ALPHA web page.

 

The MPSRC Travels to Guyana

Guyana

Dr. Karen Bailey, Dr. Brian Cameron, and Julia Pemberton recently travelled to Guyana in November 2012. Two workshops were conducted by Dr. Bailey and Julia Pemberton on Trauma Simulation and Evidence-Based Research Methodology. Dr. Bailey gave a presentation entitled Problem-Based Learning in Guyana - A Pilot Project in Surgical Clerkship at the 5th Guyana Medical Scientific Conference. Dr. Bailey was also invited to present at the Medical Council of Guyana Quarterly CME where she gave a presentation on pediatric bowel obstruction. The MSPRC has collaborated with Guyanese surgeons on numerous projects, including the Trauma Team Training and TTT update courses. Dr. Cameron has done extensive work in Guyana and continues to play an important role in surgical training in Guyana through his involvement in the Canadian Network for International Surgery (CNIS).

 

 

Fall 2012

Dr. Lorenzo Visits McMaster

Dr. Armando Lorenzo
Dr. Armando Lorenzo is a prominent urologist and clinical researcher at the Hospital for Sick Children in Toronto, and is also a former colleague of Dr. Luis Braga’s. During his visiting professorship at McMaster, Dr. Lorenzo gave a lecture at the Hamilton Golf and Country Club on Tuesday October 30th about applying lessons learned in adult urology to the practice of pediatric urology. The lecture and dinner was hosted by Dr. Braga and the McMaster Department of Surgery. Dr. Lorenzo also gave an enlightening lecture at St. Joseph’s Hospital on November 31st on decisional conflict and decisional regret among parents who consent to pediatric urology procedures for their children. Dr. Lorenzo has collaborated extensively with Dr. Braga and the MPSRC in the past, and is set to open the ALPHA study at his practice in Toronto in the near future.

 

CAPS Annual Meeting

The MPSRC recently gave four Podium Presentations at the Canadian Association of Paediatric Surgeons 2012 annual meeting in Victoria, BC. Charles Wong was awarded "best medical student presentation" for his presentation on the rates and outcomes of neonatal PDA ligation. See the presentations page for details.

 

ISD Scholarship Winner Announced

Dr. Rubini Pathy was recently awarded the inaugural International Surgery Desk Scholarship to help fund her work on an international elective within the clubfoot and orthopaedic trauma programs at Mulago Hospital in Malawi. For moe information, visit the new ISD Website.

 

Dr. Luis Braga Recieves PSI Award

Dr. Luis Braga was awarded funding from the Physicians' Services Incorporated Foundation for his work on the ALPHA trial. Dr. Braga has also begun a new partnership with Astellas Pharma for upcoming clinical research trials.

 

 

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