Dr. John-Paul Oliveria

Division of Respirology

John-Paul Oliveria

BSc, PhD

Assistant Clinical Professor (Adjunct), Division of Respirology, Department of Medicine

 

 

 

 

 

Education and Professional Standing

Dr. John-Paul Oliveria graduated from McMaster University in 2011 where he completed his BSC in the Honours Biology program with a specialization in genetics. In 2017, he completed his PhD in the Medical Sciences program with a specialization in physiology and pharmacology.

He is currently completing an interim research fellowship at McMaster University advised by Dr. Gail Gauvreau. Later this year, he will commence a postdoctoral scholar appointment at Stanford University advised by Dr. Sean Bendall.

Research Interests

Dr. Oliveria has collaborated on research projects with a few research groups, which include:

  • The Hospital for Sick Children, Division of Pediatric Emergency Medicine and Pediatric Research Academic Initiative in SickKids Emergency (PRAISE) Program
  • McMaster Children's Hospital, Division of Urology and the Clinical Urology Research Enterprise (CURE) Program
  • St. Joseph's Healthcare Center Hamilton, Division of Otolaryngology and Head and Neck Surgery
  • His current research area is allergic pathogenesis and B cell immunobiology, with current or recent studies evaluating the role of immune cells in allergic pathogenesis (IgE+ B cells, regulatory B cells or Bregs, basophils, type 2 innate lymphoid cells, eosinophils).

His research interests include:

  • The immunobiology and pathophysiology of allergic diseases (allergic asthma, allergic rhinitis)
  • The role and function of regulatory B cells in disease (autoimmunity, inflammation, cancer)
  • The role of immune cells (B cells, T cells, eosinophils, basophils) in the pathogenesis of disease
  • Single cell analyses and 'omics' technologies including: RNAseq, CyTOF, flow and imaging cytometry
  • Translational immunology, clinical drug development and clinical trials, "big data", and machine learning
  • Effectiveness of active learning in undergraduate and graduate level education

Selected Publications

LinkedIn
PubMed
Google Scholar

  1. Oliveria JP, Salter BM, MacLean J, Kotwal S, Smith A, Harris JM, Scheerens H, Sehmi R, Gauvreau GM. Increased IgE+ B cells in sputum, but not blood, bone marrow or tonsils after inhaled allergen challenge in asthmatic subjects. 2017. American Journal of Respiratory and Critical Care Medicine. 196(1):107-109. DOI: 10.1164/rccm.201611-2274LE. PMID: 28665197.
  2. Chen R, Smith SG, Salter B, El-Gammal A, Oliveria JP, Obminski C, Watson R, O'Byrne PM, Gauvreau GM, Sehmi R. Allergen-induced increase in sputum levels of group 2 innate lymphoid cells in asthmatic subjects. 2017. American Journal of Respiratory and Critical Care Medicine. [Epub ahead of print]. DOI: 10.1164/rccm.201612-2427OC. PMID: 28422515.
  3. Oliveria JP, Salter BM, Phan S, Obminski CD, Munoz CE, Smith SG, Scime TX, Watson RM, Sehmi R, Gauvreau GM. Allergic asthmatics with allergy have elevated levels of IgE+ B cells in the airways. 2017. Journal of Allergy and Clinical Immunology. 140(2):590-593.e9. DOI: 10.1016/j.jaci.2016.12.981. PMID: 28213181.
  4. Rickard M, Braga LH, Oliveria JP, DeMaria J, Romao R, Lorenzo AJ. Percent improvement in renal pelvis antero-posterior diameter (PI-APD): prospective validation and further exploration of cut-off values that predict success after pyeloplasty supporting safe monitoring with ultrasound alone. 2016. Journal of Pediatric Urology. 12(4):228.e.1-6. DOI: 10.1016/j.jpurol.2016.04.003. PMID: 27448846.
  5. El-Gammal AI, Oliveria JP, Howie K, Watson R, Mitchell PD, Chen R, Smith SG, Al-Saji D, Hawke T, Killian KJ, Gauvreau GM, O'Byrne PM. Allergen induced changes in bone-marrow and airway dendritic cells in asthmatic subjects. 2016. American Journal of Respiratory and Critical Care Medicine. 194(2):169-77. DOI: 10.1164/rccm.201508-1623OC. PMID: 26844926.
  6. Smith SG, Chen R, Kjarsgaard M, Huang C, Oliveria JP, O’Byrne PM, Gauvreau GM, Boulet LP, Lemiere C, Martin J, Nair P, Sehmi R. Increased numbers of activated group 2 innate lymphoid cells in the airways of severe asthmatics with persistent airway eosinophilia. 2015. Journal of Allergy and Clinical Immunology. 137(1):75-86.e8. DOI: 10.1016/j.jaci.2015.05.037. PMID: 26194544.
  7. Salter BM, Oliveria JP, Nusca GM, Smith SG, Watson RM, Comeau MR, Sehmi R, Gauvreau GM. Thymic stromal lymphopoietin activation of basophils in allergic asthma is IL-3 dependent. 2015. Journal of Allergy and Clinical Immunology. 136(6):1636-44. DOI: 10.1016/j.jaci.2015.03.039. PMID: 25962901.
  8. Steadman PE, Crudden J, Naranian T, Oliveria JP, Boutis K. The effectiveness of a student volunteer program for research in a pediatric emergency department. 2015. Journal of Emergency Medicine. 48(1):19-25. DOI: 10.1016/j.jemermed.2014.06.039. PMID: 25271177.
  9. Oliveria JP, Watson BM, Gauvreau GM. Chapter 10 - Bronchoprovocation tests for evaluation of drug efficacy in asthma. 2016. Advances in Pulmonary Drug Delivery. 1st Edition. CRC Press, Taylor and Francis Group, LLC. ISBN: 9781498758048. eBook ISBN: 9781315311968. DOI: 10.1201/97813153119 75-11.