Division of Neurology

Robert Hart


Professor Emeritus, Division of Neurology, Department of Medicine






Educational and Professional Standing

Robert G. Hart, M.D. is a Vascular Neurologist who trained in Neurology at the University of Missouri – Columbia before pursuing stroke fellowship training at the Oregon Health Sciences University. He directed the stroke program at the University of Texas Health Sciences Center at San Antonio for 25 years before relocating to McMaster University in 2011. He is Professor of Medicine (Neurology) at McMaster University, holds the Michael DeGroot Chair in Stroke Research, serves as co-director of the McMaster/Hamilton Health Sciences Stroke Fellowship Program, and is a Senior Scientist of Population Health Research Institute (Hamilton, Canada).

Research and Academic Interests

Dr. Hart has long-standing interests in stroke, stroke research, and clinical trials. He has directed several randomized clinical trials serving as the principal investigator of the NIH/NINDS-sponsored Stroke Prevention in A trial Fibrillation (SPAF) I, II and III trials (1987-2000) and has participated in many others (NASCET, TASS, CATS, CAPRIE, EC-IC Bypass, Canadian-American Persantine Trial, STAT, SPARCL, MATCH, PRoFESS). He was the coordinator of the Cerebral Embolism Study Group (1981-1984), Cerebral Embolism Task Force (1986-1996) and Stroke Risk in Atrial Fibrillation Working Group (2005-8). Following completion of the SPAF trials, he continues to serve as the co-principal investigator of the NIH/NINDS-sponsored Secondary Prevention of Small Subcortical Strokes (SPS3) trial. Between 2000 and 2008, he was a special consultant to the NINDS/NIH Clinical Trials Group. He was a member of the Operations and Stroke Advisory Committees of the AVERROES trial testing apixaban in atrial fibrillation. Antithrombotic therapies to prevent stroke in atrial fibrillation and especially novel oral anticoagulants a re areas of special research interest.