Dr. Sergio Borgia

Division of Infectious Diseases

Sergio Borgia

M.Sc., M.D., FRCP(C)

Assistant Clinical Professor, Division of Infectious Diseases, Department of Medicine






Education and Professional Standing

Dr. Sergio Borgia, M.Sc., M.D., FRCP(C) is an Infectious Diseases consultant at William Osler Health System in Dr. Sergio Borgia, M.Sc., M.D., FRCP(C) is an Infectious Diseases consultant at William Osler Health System in Brampton and Toronto, Ontario.  He received his Bachelor of Science degree in Microbiology from the University of Toronto where he also completed his graduate work in Medical Genetics & Microbiology at Mount Sinai Hospital studying hemolytic toxin expression of Group A Streptococci.  Dr. Borgia obtained his medical degree from Queen’s University and completed his specialty training in Internal Medicine and Infectious Diseases at McMaster University. He is a Fellow of the Royal College of Physicians of Canada and is an Assistant Clinical Professor in the Department of Medicine and Infectious Diseases at McMaster University.  In 2006, Dr. Borgia joined William Osler where he serves as a consultant for the Infection Prevention & Control Department as well as the Antimicrobial Stewardship Program. He presently holds the co-chair of the Pharmacy and Therapeutics committee.

Dr. Borgia’s clinical and research interests are in viral Hepatitis and Tuberculosis.  In care delivery for TB Dr. Borgia helped found the multi-disciplinary TB clinic in collaboration with Peel Public Health.  In Hepatitis C, Dr. Borgia’s research focuses on Integrated Cross-disciplinary models of care for viral Hepatitis. The team conducts phase 2, 3 and 4 clinical trials including burden of illness and efficacy of novel therapeutic all-oral treatment regimens. Other research areas include systematic cost-effectiveness analyses of novel Hepatitis C treatments and care delivery models.  In the area of Infection Prevention and Control, Dr. Borgia and collaborators described the first outbreak of Carbapenemase Producing Enterobacteriaceae in the Americas. 

At Osler, Dr. Borgia is the Medical Director of the Hepatitis C and Tuberculosis clinics and serves as a consultant to Peel Public Health.  He has acted as a faculty member for CARE-Liver Canada, MedScape/WebMD and has reviewed for and published in a number of peer-reviewed journals.  Dr. Borgia believes in strong patient advocacy for Peel Region’s residents and seeks to increase access to health care resources, innovative treatments, and cross-disciplinary platforms of care.

Selected Publications

Peer-Reviewed Journal Publications

  1. Sergio Borgia, MD and Adenike Rowaiye, MSc., Increased Eligibility of Treatment for Chronic Hepatitis C Infection With Shortened Duration of Therapy: Implications for Access to Care and Elimination Strategies in Canada. Canadian Journal of Gastroenterology and Hepatology, 2015;29(3):125-129.
  2. Sergio M. Borgia, Olga Lastovetska, David Richardson, Alireza Eshaghi, Rui, Xiong, Catherine Chung, Mahin Baqi, Allison McGeer, Gloria Ricci, Rachel Sawicki, Rajni Pantelidis, Donald E. Low, Roberto G. Melano, Samir N. Patel. Outbreak of Carbapenem Resistant Enterobacteriaceae Containing blaNDM-1, Ontario, Canada. Clinical Infectious Diseases, Advanced Access published September 20, 2012.
  3. Andrew DiPierdomenico, Sergio M. Borgia, David Richardson and Mahin Baqi.  Fever and Back Pain in the Returned Traveler. CMAJ 2011, 183(10), E690-692.
  4. Sergio M. Borgia, Alicia Sarabia, Jeff Fuller, and Philippe P. El-Helou. Cerebral Blastomycosis: A Case Series Incorporating Voriconazole in the Treatment Regimen. Medical Mycology, 2006, 44, 659-664.
  5. Sergio M. Borgia, Donald E. Low, Sandra Andrighetti, and Neil Rau.  Group A Streptococcal Sepsis Secondary to Peritonitis and Acute Pelvic Inflammatory Disease. European Journal of Clinical Microbiology and Infectious Diseases, 2001, 20:6, 437-9.
  6. De Azavedo JC, Yeung RH, Bast DJ, Duncan CL, Borgia SM, and Low DE. Prevalence and Mechanisms of Macrolide Resistance in Clinical Isolates of Group A Streptococci Isolated in Canada. Antimicrobial Agents and Chemotherapy, 1999, 43:9, 2144-2147.
  7. Stephen Betschel, Sergio M. Borgia, Neil Barg, Joyce de Azavedo and Donald. E. Low. Reduced Virulence of Group A Streptococcal Tn916 Mutants that do not Produce Streptolysin S. Infection and Immunity, 1998, 66:4, 1671-1679.
  8. Sergio M. Borgia, Stephen Betschel, Donald. E. Low, and Joyce C. de Azavedo. Cloning of a Chromosomal Region Responsible for Streptolysin S Production in Streptococcus pyogenesAdvances in Experimental Medicine and Biology, 1997, 418, 733-736.
  9. Mario Huesca, Sergio Borgia, Paul Hoffman, Clifford A. Lingwood, 1996. Acidic pH Changes Receptor Binding Specificity of Helicobacter pylori: a Binary Adhesion Model in which Surface Heat Shock (Stress) Proteins Mediate Sulfatide Recognition in Gastric Colonization. Infection and Immunity; 1996, 64:7, 2643-2648.

Refereed contributions (abstracts and posters)

  1. Sergio M. Borgia.  FibroScan Access in Canada: Time for Reform, A Call for Universal Access. Canadian Journal of Gastroenterology and Hepatology, May 2015.
  2. Robert P. Myers, Mel Krajden, Alnoor Ramji, Kevork Peltekian, Kelly Kaita, Paul Marotta, Sergio Borgia, Stephen Shafran, Marc Bilodeau, Mark Swain, Hemant Shah, Jordan Feld, Chris Estes, Homie Razavi, Morris Sherman.  Feasibility of Hepatitis C Virus Disease Elimination in Canada Within Two Decades. Canadian Digestive Diseases Week/Canadian Association for the Study of the Liver (CASL), Abstract #A22, Banff, Alberta, Canada, February 2015.
  3. Edward Tam, Sergio Borgia, Jo-Ann Ford, Mark Levstik, Brian Conway, Didi Emokpare, Chris Steingart, Nir Hilzenrat, Alnoor Ramji, Curtis Cooper, Marie-Louise Vachon, Jodi Halsey-Brandt, Jean-François Pouliot for the SIMPLE Study Group. An Observational Study Investigating the Management of G1 Hepatitis-C Adults Patients with Boceprevir in Combination with PegIFN/RBV in Canada (The S.I.M.P.L.E. Study). Poster and Oral CASL-CDDW, Toronto, Ontario, 2014.
  4. S. AlQahtani, S. Borgia, Wm. Ciccotelli, N. Spitale, A. Xaun and D. Cook. Severe Sepsis Management: Compliance with three Interventions. Abstract and Talk.  University of Western Ontario-McMaster Joint Critical Care Symposium, London Health Sciences Centre, London, Ontario, June 2004.
  5. Sergio M. Borgia, Christine Lee and Philippe El-Helou. Epstein-Barr Virus Infectious Causing Infectious Mononucleosis, Hepatitis and Hemolytic Anemia. 14th Annual Residents’ Research Day in Medicine. (Abstract and Poster #11) Royal Botanical Gardens, Burlington, Ontario, May 2003.
  6. S.M. Borgia, D.J. Bast, S.D. Betschel, D.E. Low and J.C.S. de Azavedo. Characterization of an Open Reading Frame (sagA) Necessary for Streptolysin S Production in Streptococcus pyogenes. Streptococcal Genetics Conference, Nice, France, 1998.
  7. Sergio M. Borgia, Stephen Betschel, Donald. E. Low, and Joyce C. de Azavedo Identification of a Novel Open Reading Frame Involved In Streptolysin S Production In Group A Streptococcus. 37th Interscience Conference on Antimicrobial Agents and Chemotherapy, Toronto, Canada, September 1997. (ICCAC).