Division of Hematology & Thromboembolism

Lori-Ann Linkins

M.D., F.R.C.P.(C).

Assistant Professor, Division of Hematology and Thromboembolism, Department of Medicine

 

 

Education and Professional Standing

Masters in Health Research Methodology, McMaster University(in progress)
F.R.C.P.(C). Hematology, 2000
F.R.C.P.(C). Internal Medicine, 1999
M.D., McMaster University, 1995

Biography

Dr. Linkins received her medical degree from McMaster University in 1995. After completing her Hematology residency at McMaster University in 2000, she began a research fellowship in Thromboembolism at the Juravinski Hospital and Cancer Centre in Hamilton. In 2004, she joined the Faculty of Medicine at McMaster as a consultant on Venous Thromboembolism for the Division of Hematology and Thromboembolism (Assistant Professor). Dr. Linkins obtained her Masters degree in Health Research Methodology at McMaster in 2005. She has been the recipient of Research Fellowship awards from the Thrombosis Interest Group of Canada, the Canadian Institutes of Health Research, and the Heart & Stroke Foundation of Canada.

Research Interests

Dr. Linkins’ research interests include the diagnosis of deep vein thrombosis, bleeding on anticoagulant therapy, and diagnosis of heparin induced thrombocytopenia. She is currently the PI on two clinical trials funded by the Heart & Stroke Foundation of Canada. One study is a 2000 patient multicentre trial that is evaluating a new way of using D-dimer assays, in combination with clinical pretest probability, to diagnose deep vein thrombosis. The other study is a 500 patient trial that is evaluating how a clinical score and rapid immunoassay can be combined to improve the way heparin-induced thrombocytopenia is diagnosed in the clinical setting. She is also PI on a locally funded study that will use a decision board to help patients with idiopathic venous thromboembolism decide whether or not to continue anticoagulant therapy. Her research is currently supported by an internal career award from the Department of Medicine at McMaster University.

Selected Publications

  1. Linkins LA, Bates SM, Ginsberg JS, Kearon C. Use of different D-dimer levels to exclude venous thromboembolism depending on clinical pretest probability. J of Thromb Haemost 2004;2:1256-1260.
  2. Linkins LA, Pasquale P, Paterson S, Kearon C. Change in thrombus length on venous and recurrent deep vein thrombosis. Arch Intern Med 2004;164:1793-1796.
  3. Linkins LA, Choi P, Douketis JD. What is the clinical impact of bleeding in patients with venous thromboembolism who are receiving oral anticoagulant therapy? A meta-analysis investigating case-fatality and intracranial bleeding risk. Ann Intern Med 2003;139:893-900.