Division of Geriatric Medicine


Janet Pritchard Phd (c) is a student in the Medical Sciences Programme and Department of Medicine, Division of Geriatric Medicine – St Peters Hospital. She was awarded the "American Society for Bone and Mineral Research President's Poster Competition Award" for her research.

Project Title: Longitudinal changes in trabecular bone microarchitecture in postmenopausal women with and without type 2 diabetes

Key points:

  • Although women with type 2 diabetes have higher than normal bone mineral density (BMD) compared to women without type 2 diabetes, the risk of osteoporotic fracture is greater for women with type 2 diabetes
  • Whole bone strength is dependent on factors, in addition to BMD, such as trabecular bone microarchitecture, which can be assessed using MRI technology
  • Over 2 years, there was a greater increase in the number of holes in the trabecular bone at the wrist in women with type 2 diabetes compared to women without type 2 diabetes, which could explain why the risk of fracture is greater in adults with type 2 diabetes

Andy Kin On Wong Phd (c) is an interdisciplinary scientist at McMaster University Department of Medical Sciences - and has a combination of expertise in pharmacology, diagnostic imaging with MRI and QCT, as well as epidemiology and biostatistics. Andy is the director of the Canadian Multicentre Osteoporosis Bone Quality Study (CaMos BQS @ http://bqs.camris.ca) held at six cities in Canada. He received the Young Investigator Travel Award at the 2012 American Society for Bone and Mineral Research (ASBMR) this year for his work relating muscle density / adiposity to fragility fractures in a pilot sample of the CaMos study. With his series of projects on bone and muscle, Andy was selected to give two oral presentations - at the plenary opening reception and at the bone and muscle working group. Andy's work is funded by the Vanier Canada Graduate Scholarship and a CIHR operating grant.

Key Points:

  • muscle adiposity represents up to 53% of the variance in the muscle density measurement obtained by peripheral QCT
  • after adjusting for adiposity using MRI, a lower muscle density remains significantly associated with a higher odds for fragility fractures
  • there may be features of muscle beyond its fat, such as fibre density and mitochondrial population, that may be related to fractures

Courtney Kennedy Phd (c ) is a Research Methodologist in the Department of Medicine, Division of Geriatric Medicine – St. Peters Hospital, and student in Health Research Methodology in the Department of Clinical Epidemiology and Biostatistics at McMaster. Courtney recently received a Young Investigator Annual Meeting Travel Grant at the 2012 American Society for Bone and Mineral Research (ASBMR), and had a plenary poster in the opening reception, for her work exploring frailty and bone health in the Canadian Multicentre Osteoporosis Study (CaMos).  Her frailty work was supported by an Osteoporosis Canada-CaMos Fellowship Award (2011-2012), and she was awarded this fellowship again in 2012-2013 to continue this work.

Key Points:

  • A cumulative deficits frailty index created in the CaMos cohort demonstrated external and construct validity
  • In the cross-sectional study, CaMos men and women with falls, women with prevalent fractures, men with OP were frailer
  • Further longitudinal analyses are being conducted to examine how frailty relates to muscle measures and how it progresses for participants with low BMD and fractures

Courtney’s supervisory team includes: Dr. Lehana Thabane, Professor/Associate Chair, Department of Clinical Epidemiology & Biostatistics at McMaster University and Senior Scientist, Population Health Research Institute (PHRI), Hamilton Health Sciences;  Dr. Alexandra Papaioannou, a Geriatrician with Hamilton Health Sciences and Professor, Department of Medicine and Eli Lilly Canada Chair in Osteoporosis,  McMaster University; andDr. Jonathan D. Adachi, Professor, Department of Medicine and Alliance for Better Bone Health Chair in Rheumatology, McMaster University and Director of the Hamilton Arthritis Centre, St. Joseph's Healthcare.

The Geriatric Education and Research in Aging Sciences (GERAS) Centre is pleased to announce a new Post Doctoral Fellow research award under the supervision of Dr. Alexandra Papaioannou. This is a joint venture between McMaster University (Department of Medicine) and Hamilton Health Sciences Foundation. The successful candidate will receive hands-on training in the area of bone health and frailty and the opportunity to collaborate with national and international leaders in the field.

For more information about the qualifications and application process for this new research award, please click here.