Dr. Sanjit Jolly

Division of Cardiology

Sanjit Jolly

Associate Professor, Division of Cardiology, Department of Medicine

 

 

 

 

 

 

Education and Professional Standing

Dr. Jolly completed his Bachelor of Science degree at the Queens’ University, Kingston, Ontario. Medical school, internal medicine residency, and cardiology fellowship training were all completed at University of Toronto, Ontario.  Subsequently, he has completed an interventional cardiology fellowship at both: St. Michael’s Hospital, University of Toronto and Hamilton Health Sciences, McMaster University. Dr. Jolly is a fellow of the Royal College of Physicians and Surgeons of Canada, with certification in internal medicine and cardiology. 

Clinical Interests

Dr. Jolly is a fulltime interventional cardiologist at Hamilton Health Sciences.  He specializes in chronic total occlusion PCI.  He is actively involved in postgraduate medical training of residents and fellows in invasive angiography, angioplasty, general cardiology, and internal medicine.

Research Interests

He has formal training in clinical trials with a M.Sc. in Health Research Methodology from McMaster University.  His particular research interest is in multicenter randomized clinical trials in acute coronary syndromes and interventional cardiology.  He was the principal investigator for the RIVAL trial, an international multicenter trial of 7000 patients comparing radial vs. femoral access for coronary intervention. He was the principal investigator of the landmark TOTAL trial (n=10,732) an international, multicenter randomized trial of thrombus aspiration with PCI vs. PCI alone for patients with STEMI.

Selected Funding

  • TOTAL trial, a randomized trial of routine aspiration thrombectomy vs PCI alone during primary PCI for STEMI, Canadian Institutes of Health (CIHR) and Medtronic
  • Radiation Protect Study: Randomized Controlled Trial of Radiation Protection Witha Patient Lead Shield and a Novel, Non-lead Surgical Cap for Operators Performing, AFP Cardiology Award, Mc Master University
  • RIVAL trial, a randomized trial of radial vs. femoral access for coronary intervention, CANNeCTIN, Canadian Network and Centre for Trials internationally

Selected Publications

  1. Jolly SS, Cairns JA, Yusuf S, Rokoss MJ, Gao P, Meeks B, Kedev S, Stankovic G, Moreno R, Gershlick A, Chowdhary S, Lavi S, Niemela K, Bernat I, Cantor WJ, Cheema AN, Steg PG, Welsh RC, Sheth T, Bertrand OF, Avezum A, Bhindi R, Natarajan MK, Horak D, Leung RC, Kassam S, Rao SV, El-Omar M, Mehta SR, Velianou JL, Pancholy S, Džavík V; TOTAL Investigators. (2015). Outcomes after thrombus aspiration for ST elevation myocardial infarction: 1-year follow-up of the prospective randomized TOTAL trial. Lancet. 6736: 0044801.
  2. Alazzoni A, Gordon CL, Syed J, Natarajan MK, Rokoss M, Schwalm JD, Mehta SR, Sheth T, Valettas N, Velianou J, Pandie S, Al Khdair D, Tsang M, Meeks B, Colbran K, Waller E, Fu Lee S, Marsden T, Jolly SS. (2015). Randomized Controlled Trial of Radiation Protection With a Patient Lead Shield and a Novel, Nonlead Surgical Cap for Operators Performing Coronary Angiography or Intervention. Circ Cardiovasc Interv.8: 002384.
  3. Jolly SS, Cairns JA, Yusuf S, Meeks B, Gao P, Hart RG, Kedev S, Stankovic G, Moreno R, Horak D, Kassam S, Rokoss MJ, Leung RC, El-Omar M, Romppanen HO, Alazzoni A, Alak A, Fung A, Alexopoulos D, Schwalm JD, Valettas N, Dzavik V; TOTAL Investigators. (2015). Stroke in the TOTAL trial: a randomized trial of routine thrombectomy vs. percutaneous coronary intervention alone in ST elevation myocardial infarction. Eur Heart J. 36: 2364-72.
  4. Jolly SS, Cairns JA, Yusuf S, Meeks B, Pogue J, Rokoss MJ, Kedev S, Thabane L, Stankovic G, Moreno R, Gershlick A, Chowdhary S, Lavi S, Niemela K, Steg PG, Bernat I, Xu Y, Cantor WJ, Overgaard CB, Naber CK, Cheema AN, Welsh RC, Bertrand OF, Avezum A, Bhindi R, Pancholy S, Rao SV, Natarajan MK, Ten Berg JM, Shestakovska O, Gao P, Widinsky P, Dzavik V.(2015). Randomized Trial of Primary PCI with or without Routine Manual Thrombectomy.N Engl J Med. 372: 1389-98.
  5. Jolly SS, Cairns J, Yusuf S, Niemela K, Steg PG, Worthley M, Ferrari E, Cantor WJ, Fung A, Valettas N, Rokoss M, Olivecrona GK, Widimsky P, Che. (2014). Procedural volume and outcomes with radial or femoral access for coronary angiography and intervention. J Am Coll Cardiol.63: 954-63.
  6. Jolly SS, Cairns J, Yusuf S, Meeks B, Shestakovska O, Thabane L, Niemelä K, Steg PG, Bertrand OF, Rao SV, Avezum A, Cantor WJ, Pancholy SB, Moreno R, Gershlick A, Bhindi R, Welsh RC, Cheema AN, Lavi S, Rokoss M, Džavík V. (2014). Design and rationale of the TOTAL trial: A randomized trial of routine aspiration ThrOmbecTomy with percutaneous coronary intervention (PCI) versus PCI ALone in patients with ST-elevation myocardial infarction undergoing primary PCI.American heart journal. 167: 315-321.
  7. Jolly SS, Cairns J, Niemela K, Steg PG, Natarajan MK, Cheema AN, Rao SV, Cantor WJ, Džavík V, Budaj A, Sheth T, Valentin V, Fung A, Widimsky P, Ferrari E, Gao P, Jedrzejowski B, Mehta SR,. (2013). Effect of radial versus femoral access on radiation dose and the importance of procedural volume: a substudy of the multicenter randomized RIVAL trial.JACC. Cardiovascular interventions. 6:258-66.
  8. Jolly SS, Yusuf S, Cairns J, Niemelä K, Xavier D, Widimsky P, Budaj A, Niemelä M, Valentin V, Lewis BS, Avezum A, Steg PG, Rao SV, Gao P, Afzal R, Joyner CD, Chrolavicius S, Mehta SR,. (2011). Radial versus femoral access for coronary angiography and intervention in patients with acute coronary syndromes (RIVAL): a randomised, parallel group, multicentre trial.Lancet. 377: 30.
  9. Jolly SS, Niemelä K, Xavier D, Widimsky P, Budaj A, Valentin V, Lewis BS, Avezum A, Steg PG, Rao SV, Cairns J, Chrolavicius S, Yusuf S, Mehta SR. (2011). Design and rationale of the radial versus femoral access for coronary intervention (RIVAL) trial: a randomized comparison of radial versus femoral access for coronary angiography or intervention in patients with acute coronary syndromes.American heart journal. 161: 254-260.
  10. Steg PG, Jolly SS, Mehta SR, Afzal R, Xavier D, Rupprecht HJ, Lopez-Sendon JL, Budaj A, Diaz R, Avezum A, Widimsky P, Rao SV, Chrolavicius S, Meeks B, Joyner C, Pogue J, Yusuf S. Low-dose vs standard-dose unfractionated heparin for percutaneous coronary intervention in acute coronary syndromes treated with fondaparinux: the FUTURA/OASIS-8 randomized trial. JAMA. Sep 22;304(12):1339-49. 2010.