McMaster University

McMaster University

Faculty of
Health Sciences

SCC-RI Lab

Research Facilities

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Biosafety Lab Level 3

Web: Biosafety Lab Level 3

McMaster's Biosafety Level 3 (BSL3) Lab is one of the few centres in Canada equipped to support research on infectious disease and the world's most deadly pathogens. The 1,400-square-foot Lab boasts dedicated animal facilities, a state-of-the-art flow cytometry facility and ample space for current and future projects. It meets all government laboratory biosafety guidelines, and holds an import permit allowing for the exchange of BSL3 materials with other certified facilities within and outside of Canada. The Lab's services are available for a fee to researchers across the University, as well as other academic institutions and the private sector.

DNA Profiling/Gene Expression Profiling Laboratory

McMaster's DNA Profiling/Gene Expression Profiling Laboratory is a core facility which is presently undergoing expansion and relocation to the Michael G. DeGroote Centre for Learning and Discovery. The expanded facility will comprise wet and dry laboratories in which expression profiling will be used as both a gene discovery tool and as a means to analyse global responses of cells to external stimuli such as candidate drugs.

Centre for Microbial Chemical Biology (CMCB)

Web: Centre for Microbial Chemical Biology (CMCB)

The Centre for Microbial Chemical Biology (CMCB) supports cross-disciplinary research between scientists in the departments of biochemistry and biomedical sciences, biology, chemistry and chemical biology, and geography and earth sciences, focusing on new applications in infection control from diagnostics to new drug discoveries.

Electron Microscopy Facility

Web: Electron Microscopy Facility

The Electron Microscopy Facility provides an inter-disciplinary approach to the investigation of Biological, Biochemical, Clinical and Medical areas of research. The facility offers consulting, experimental design, training and technical services for light and electron microscopic imaging, immuno-labeling, image analysis, morphometry, and elemental analysis. It is the largest diagnostic EM Facility in the Canada.

Farncombe Family Axenic-Gnotobiotic Facility

McMaster University is home to the Farncombe Family Axenic-Gnotobiotic Facility, Canada's only gnotobiotic research facility with axenic embryo transfer capabilities. This 3,000-square-foot laboratory provides a controlled, germ-free environment in which to study host-microbial interactions. In addition to generating and housing gnotobiotic animals on prescribed genetic backgrounds for internal and external clients, the Facility is unique in that it has the capacity and infrastructure to enable the performance of long-term experimentation under controlled environmental conditions in diverse areas of biomedical sciences.

Website: Farncombe Family Axenic-Gnotobiotic Facility

Flow Cytometry Facility

Web: Flow Cytometry Facility

The Flow Cytometry Facility in the McMaster Immunology Research Centre (MIRC) provides a centralized service in flow cytometry to investigators at McMaster and is available to customers from outside the University. Flow cytometry is a highly technical specialized resource employed by both immunologists and cell biologists that require expensive instrumentation. Our core facility seeks to facilitate access to this powerful technology by offering our equipment on a fee-per-use basis. We also offer an experienced technologist who can process specimens and run the analytical equipment for inexperienced users.

High Content Screening Laboratory/Molecular Imaging

Web: High Content Screening Laboratory/Molecular Imaging

The new High Content Screening (HSC) Laboratory is currently under construction in McMaster's Health Sciences Centre. In this unique facility, cells will be manipulated either genetically or chemically and assessed rapidly.

High Throughput Screening Laboratory

The High Throughput Screening Laboratoary's Integrated Beckman Robotics System can simultaneously perform more than 300 separate experiments, plus more than 60 controls, in wells no larger than a raindrop. Nearly 100,000 compounds can be investigated in only a few days. The laboratory is one of only a few of its kind in North America. The HTS laboratory is housed in the Health Sciences Centre, in a 1,400-square-foot area that was specifically designed and renovated for the facility.

Histopathology Lab

Web: Histopathology Lab

The Histopathology Lab provides technical and theoretical assistance to researchers in the area of Molecular Immunology, Virology and Inflammation. Faculty, post-doctoral fellows and graduate students make use of the technical expertise and equipment available in the lab. Histological and Immunohistochemistry analysis is provided by trained technicians as required by researchers. The Histopathology Lab is funded by the Centre for Gene Therapeutics, which primarily makes use of its services and facilities.

Human Movement Laboratory

Web: Human Movement Laboratory

In the summer of 1992, the School of Rehabilitation Science, in concert with the Faculty of Health Sciences and McMaster University, received a $143,400 grant from the Ministry of Colleges and Universities to develop a facility to educate health care professionals about human movement assessment. The Human Movement Laboratory examines 3D human movement with concentration on pathological, normal and athletic motion. They are able to carry out highly sensitive motion analysis through use of state-of-the-art instrumentation.

Integrated Microscopy Facility

Web: Integrated Microscopy Facility

The Integrated Microscopy Facility at McMaster University provides an inter-disciplinary approach to the investigation of Biological, Biochemical and Medical areas of research. The experienced staff offers consulting, experimental design, training and technical services for light and electron microscopic imaging, immunolabeling, image analysis, morphometry, freeze fracture and elemental analysis. The facility is the largest diagnostic Electron Microscopy unit in the country.

McMaster Genome Facility

Web: McMaster Genome Facility

The McMaster Genome Facility provides high-quality, affordable, cutting-edge genomics services. Our labs are equipped with the latest technology to perform a range of experiments, including next generation sequencing, microarray analysis, and bioinformatics. These services are available to researchers at McMaster University, as well as academic and non-academic users locally, nationally and internationally, on a fee-for-service basis. Our technical staff can also assist in the setup and design of experiments.

McMaster Regional Centre for Mass Spectrometry

Web: McMaster Regional Centre for Mass Spectrometry

The McMaster Regional Centre for Mass Spectometry consist of five mass spectrometers. The facility is operated by a professional manager, a research scientist, a Bio MS specialist and two technologists, who provide mass spectrometric service by analysing approximately 4,000 individual samples per year for many client within the McMaster community and at various external institutions.

Mobix Lab

Web: Mobix Lab

MOBIX is a world-class centre for life science and translational research . It provides molecular biology expertise and services to the research community both inside and outside McMaster University. MOBIX consists of a series of centre, each with its own experimental and developmental goals, and all sharing the common vision.

Nuclear Magnetic Resonance Laboratory

Web: Nuclear Magnetic Resonance Laboratory

The Nuclear Magnetic Resonance Laboratory is highly regarded in the Canadian chemical community for its versatility in the types of samples as well as the number of nuclei that can be studied by solution and solid state NMR. With seven instruments housed in modern laboratories and valued at approximately $7 million, it is one of the most versatile and best equipped facilities of its kind in Canada. In terms of number of users, it ranks among the top 10 per cent of such facilities in North America.

Occupational and Environmental Health Laboratory

Web: Occupational and Environmental Health Laboratory

The Occupational and Environmental Health Laboratory (OEHL) was established in 1979 at McMaster University to provide occupational hygiene services to industry, labour and the general public. The OEHL is a specialized analytical laboratory and their personnel are trained specifically in the analysis and interpretation of samples taken in the workplace and outdoor environments. The laboratory is equipped to analyze fibres, particulates, metals, organics and inorganics.

Prototype Machine Shop

Web: Prototype Machine Shop

The BioMedical Prototype Machine Shop specializes in basic prototype work with a straight forward approach, aimed at getting the job done. For the most part the shop is a one person operation, and its current Technical Manager is Vertram Visheau. His duties entail providing technical support to more than 100 faculty members of Health Sciences, plus (to a lesser extent), other universities, hospitals, and biotechnology companies involved in basic and clinical research.

Radiochemical Laboratory for PET Radiopharmaceuticals

Web: Radiochemical Laboratory for PET Radiopharmaceuticals

The Radiochemical Laboratory is an integral part of the McMaster Positron Emission Tomography (PET) Program. Their laboratory is equipped with a negative ion cyclotron (Siemens RDS-112), remotely controlled and automated units for radiochemical synthesis and state-of-the-art analytical equipment for quality control. The laboratory is staffed by two senior Radiochemists, a Radiochemist and one quality control Chemist.

Robert E. Fitzhenry Vector Laboratory

Web: Robert E. Fitzhenry Vector Laboratory

The new Robert E. Fitzhenry Vector Laboratory is the only one of its kind at an academic centre in Canada, and one of a few in North America. The new lab, located in the Michael G. DeGroote Centre for Learning and Discovery, will give McMaster researchers the capacity to ensure the identity, potency, safety and purity of pharmaceutical products, and to produce vectors safe for use in clinical trials.

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