About 40 per cent of the population have a genetic disposition to celiac disease, but only about one per cent develop the autoimmune condition when exposed to gluten, and this could be promoted by the type of bacteria present in the gut.
Researchers at McMaster University have found that gluten, a common protein in the Western diet which is not well digested by the gut enzymes, could be metabolized by bacteria.
The scientists of the Farncombe Family Digestive Health Research Institute at McMaster University discovered that mice that harboured in their gut the opportunistic bacteria Pseudomonas aeruginosa (Psa) isolated from celiac patients, metabolized gluten differently than mice treated with Lactobacillus, often used in probiotics.
A McMaster graduate has left the University his library, a scholarship fund, and his Westdale home to be used as a laboratory.
“This will be a living laboratory,” says Qiyin Fang, Canada Research Chair in Biophotonics at McMaster. He will lead a unique research project in 2017, retrofitting the interior of the house to develop and test smart technology that will enable older people to live in their homes longer.
Located a block from main campus, the house was the family home of Ernest Kay ’47, ’49, who moved there with his parents in 1936. A lifelong supporter of his alma mater, Kay has left a bequest valued at more than $1.8 million, which includes his library collection, funds to augment a scholarship he established in 1999, and his two-storey Westdale home.
A study led by McMaster University researchers has found that, contrary to recent reports, flu nasal sprays provide similar protection against influenza as standard flu shots.
Published today in the scientific journal Annals of Internal Medicine, the study shows that the nose spray had a similar effect to the standard flu shot. Previous recommendations from the Centers for Disease Control’s Advisory Committee on Immunization Practices (ACIP) had previously called for nasal sprays, or live attenuated influenza vaccine (LAIV), not be used during the 2016-2017 flu season.
Dr. Mark Loeb, lead author of the study, says his team’s findings challenge the ACIP’s recommendations towards flu shots, or inactivated vaccines.