McMaster University

McMaster University

A surgeon holds a globe in their hands, signifying the international aims of the McMaster Centre for Evidence Based Orthopedics.

Centre for Evidence-Based Orthopaedics

Welcome to the Centre for Evidenced-based Orthopaedics

The Centre for Evidence-Based Orthopaedics (CEO) was established in 2012 by Dr. Bhandari. The vision is simple: CEO will improve patient care by producing high-quality clinical research that will answer clinically relevant questions. Since its establishment, CEO has already gained recognition as a leading research centre for evidence-based orthopaedics. CEO will continue to strive to improve the lives of persons with orthopaedic injuries, conditions, and disorders around the world by identifying and disseminating novel therapies through the conduct of high quality, collaborative research initiatives.

Research Units

Trauma and Injury

Unit Heads

A photo link to the bio of Dr. Brad Petrisor

Dr. Brad Petrisor

A photo link to the bio of Dr.Bill Ristevski

Dr. Bill Ristevski

There are three themes within the trauma and injury research unit:

Degenerative Joint Disease

Unit Head

A photo link to the bio of Dr.Justin de Beer

Dr. Justin de Beer

Osteoarthritis is one of the top ten diseases causing disability in individuals of developed countries. The World Health Organization estimates that 9.6% of men and 18.0% of women over 60 years of age suffer from osteoarthritis.

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Musculoskeletal Tumor Surgery

Unit Heads

A photo link to the bio of Dr. Michelle Ghert

Dr. Michelle Ghert

A photo link to the bio of Dr. Ben Deheshi

Dr. Ben Deheshi

Malignant bone tumors (bone sarcomas) often affect adolescents and young adults. Care of patients with bone sarcomas is carried out in specialty centers, as these are rare forms of cancer. In Canada, bone sarcomas affect 4 to 5 patients per million persons each year.

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Sports Medicine

Unit Head

A photo link to the bio of Dr. Femi Ayeni

Dr. Femi Ayeni

Sports related injuries account for 30 to 40 percent of all unintentional injuries, and sports accidents are the leading cause of injury in young adults. With approximately 30 million children and adolescents participating in sports activities according to the U.S. Centers for Disease Control, the prevalence of sports injury is on the rise.

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Disorders of the Spine

Unit Head

A photo link to the bio of Dr. Brian Drew

Dr. Brian Drew

There are currently 200,000 individuals with spinal cord injury in the United States, with 12,000-20,000 new injuries annually or 40 individuals per one million individuals in the population. The main causes of spinal cord injury can be categorized into four major categories: motor vehicle accidents (46%), falls (22%), violence (16%) and sports (12%).

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Research Themes

The rationale for the five major themes, each with their unique foci, is driven by the increasing global burden of orthopaedic trauma injuries worldwide due to the prevalence of road traffic injuries, the crisis of intentional injuries in women from domestic violence, the epidemic of fragility fractures in the elderly, the high rates of osteoarthritis, the devastating effects of bone cancer, the debilitating results of an orthopaedic sports injury, and high level of disabilities resulting from spinal injuries and conditions. These debilitating injuries and disorders affect people of all ages, from children to the elderly. Each of these core research themes are operationalized primarily by the conduct of multi-national definitive randomized controlled trials and large observational cohort studies.

Changing orthopaedic practice around the globe utilizing the principles of evidenced-based orthopaedics - Dr. Mohit Bhandari, Executive Director

Building on our Research Successes

MacOrtho is a world leader in clinical research in the field of orthopaedic surgery. Under the leadership of Dr. Mohit Bhandari, MacOrtho research is at the forefront of a paradigm shift in how orthopaedic research is being conducted world-wide. Ten years ago, orthopaedic surgery trials were typically single-centre initiatives which included...

The Organization of the Centre for Evidence-Based Orthopaedics

The CEO is currently led by the Founding Executive Director (Dr. Bhandari). Each research unit is led by a Unit Head who provides oversight for the research activities within the unit. All Unit Heads serve on the Steering Committee.

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