Our Research Edge

The Department of Clinical Epidemiology and Biostatistics boasts a rich array of scholarly disciplines interacting across a broad range of research areas:

Public and Population Health

Public and Population Health is focused on understanding the complex and interrelated determinants of health and health inequalities in individuals, communities and populations, and the application of this knowledge to promote, protect, and restore health.

There are two degree programs within CE&B concerned with Public and Population Health: Health Research Methodology, and Public Health & Preventive Medicine

Within the Health Research Methodology program, Public and Population Health is a field of specialization. The field of public and population health provides students with the methodological expertise needed to conduct cutting edge research, including investigations into the biological, economic, and social factors that protect, precipitate or perpetuate disability and disease, and to improve public health.

Public and Population Health

The second degree program within CE&B concerned with Public and Population Health is Public Health & Preventive Medicine

This academic and community-based program is built on the principles of population health, all levels of disease prevention, health promotion and protection. It prepares physicians to function flexibly and effectively in leadership roles in a wide variety of community health and academic/research settings with special emphasis on:

  • Health needs assessment
  • Evidence-based community health practice
  • Applied research and program evaluation
  • Economic evaluation and health policy analysis
  • Occupational and environmental health
Public and Population Health

Six research groups associated with CE&B study Public and Population Health issues.

  • Canadian Longitudinal Study on Aging (CLSA)
  • Population Genomics Program (PGP)
  • Population Health Research Institute (PHRI)
  • System-Linked Research Unit on Health and Social Service Utilization (SLRU)
  • Health Utilities Group (HUG).
  • Offord Centre
Public and Population Health

One research group associated with CE&B that investigates Public and Population Health issues is the Canadian Longitudinal Study on Aging (CLSA).

CLSA

The Canadian Longitudinal Study on Aging is a large, national, long-term study that will follow approximately 50,000 men and women between the ages of 45 and 85 for at least 20 years.

The CLSA will collect information on the changing biological, medical, psychological, social, lifestyle and economic aspects of people’s lives. These factors will be studied in order to understand how, individually and in combination, they have an impact in both maintaining health and in the development of disease and disability as people age.

Public and Population Health

A second research group associated with CE&B concerned with Public and Population Health is the Population Genomics Program.

PGP

The Population Genomics Program (PGP) mobilizes McMaster University's expertise and resources in population health, genomics, clinical trials and health-research methodology to investigate the influences of gene-gene and gene-environment interactions on disease.

These studies at the University and Hamilton Health Sciences collectively serve as excellent resources to study genetic associations with common complex diseases, but will take sophisticated methodological approaches to reliably assess them.

Biostatistics

Biostatistics specializes in the development of new statistical methodologies and the application of existing ones, "from proof to practice," for the design and analysis of quantitative and qualitative research studies.

Within CE&B, the Health Research Methodology program's Biostatistics PhD field is specially designed for applicants with an MSc in Mathematics and/or Statistics who wish to pursue doctoral work in Biostatistics.

Biostatistics

The Health Research Methodology (HRM) Biostatistics program aims to provide trainees with the skills they need to conduct independent research into biostatistical topics, provide leadership as biostatistical collaborators in clinical, health systems and population health investigations, and effectively teach biostatistics from introductory through to advanced levels.

Graduates will possess the following skills:

  • The ability to apply biostatistical concepts, techniques and data-analytic strategies across the full spectrum of research questions and study designs
  • The ability to contribute to grant proposals in the areas of research design, data analysis and interpretation
  • The ability to teach biostatistical concepts to research colleagues who are not biostatisticians
  • The ability to adapt existing statistical techniques or to develop new techniques to solve research design and analytical programs
Biostatistics

Members of the CE&B Biostatistics Caucus will consult on research design at the outset of a research program, and on statistical analyses of research data.

The Biostatistics Unit at St. Joseph's Healthcare, led by Dr. Lehana Thabane, caters to researchers in the Father Sean O'Sullivan Research Centre, but also offers advice to other Health Sciences faculty members and business clients.

Biostatistics Caucus
Biostatistics Caucus
Joseph
Beyene
Gary Foster Lauren Griffith Jemila Hamid Steve Hanna Janice Pogue
Eleanor Pullenayegum Rob Roberts Harry Shannon Lehana Thabane Stephen Walter Changchun Xie
Noori Akhtar-Danesh Angelo Canty Gregory Pond      
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  • Health Economics

    Health Economics is the study of how scarce resources are allocated among alternative uses for the care of sickness and the promotion, maintenance and improvement of health.

    Health Economics includes the study of how health care and health related services, their costs and benefits, and health itself are distributed among individuals and groups in society.

    Within CE&B's Health Research Methodology program, the highly-flexible HRM Classic field encourages explorations in Health Economics.

    Four research groups associated with CE&B examine Health Economics issues:

    • Centre for Health Economics and Policy Analysis (CHEPA)
    • Centre for Evaluation of Medicines (CEM)
    • Programs for Assessment of Technology in Health (PATH)
    • Health Utilities Group (HUG).
    Public and Population Health

    A third research group associated with CE&B and concerned with Public and Population Health is the Population Health Research Institute (PHRI).

    PHRI

    Founded in 1999 as a joint Institute of Hamilton Health Sciences Corporation and McMaster University, the PHRI is now the largest and most cited academic cardiovascular research group in Canada. Its vision is to conduct large simple studies to address questions of international importance and relevance.

    The Population Health Research Institute is home to more than 250 researchers, physicians, scientists, epidemiologists, biostatisticians, rehabilitation experts, nutrition scientists, research coordinators, allied health professionals, and quality assurance personnel, as well as research and administrative support personnel.

    Public and Population Health

    Another research group associated with CE&B and concerned with Public and Population Health is the System-Linked Research Unit on Health and Social Service Utilization (SLRU).

    SLRU

    The SLRU is a group of university based researchers and community partners dedicated to helping health and social service agencies create new solutions for problems affecting vulnerable children, adults, and seniors.

    The service partners include the regional health and social service departments, social planning councils, home care nursing services, health service and mental health organizations, children’s services, and others.

    Public and Population Health

    A further research group associated with CE&B and concerned with Public and Population Health is the Health Utilities Group (HUG).

    HUG

    The Health Utilities Group is a multi-disciplinary group of researchers and scientists based in the Department of Clinical Epidemiology and Biostatistics (CE & B) at McMaster University, Hamilton, Canada. HUG develops and applies systems for measuring the health status and health-related quality of life of individuals, clinical groups and general populations. The HUG team meets on a regular basis to plan and manage research projects related to developing and applying tools for measuring health status and health-related quality of life utility scores.

    HUG members developed the Health Utilities Index (HUITM) "family" of classification and preference-based scoring functions during the past 20 years. The HUITM has been included in more than 200 clinical studies, and every major Canadian general population health survey since 1990. The HUI group co-operates internationally with informal groups in France, the U.K., the Netherlands, Austria, Japan, and Singapore.

    Public and Population Health

    An important research group associated with CE&B and concerned with Public and Population Health is the Offord Centre.

    Offord Centre

    The Offord Centre for Child Studies is researching why some young people are able to overcome enormous obstacles and grow up to be well-adjusted and productive adults whereas others cannot.

    The Centre is also developing, implementing and assessing a number of promising, cost-effective, early interventions to treat and prevent destructive emotional and behavioural problems in our children and youth.

    Clinical Epidemiology

    Clinical epidemiology is the application of epidemiologic and biometric methods to the study of problems of patient management (including diagnosis, prognosis, and therapy) encountered in the clinical delivery of care to patients.

    Within CE&B's Health Research Methodology program, Clinical Epidemiology is a field of specialization. Individuals training in clinical epidemiology work alongside world-leading clinical epidemiologists, who are conducting their research in multiple sites around the world and changing the way medicine is practiced globally.

    Clinical Epidemiology

    Seven research groups associated with CE&B examine Clinical Epidemiology issues:

    • Clinical Advances through Research and Information Translation (CLARITY)
    • Centre for Evaluation of Medicines (CEM)
    • Neonatal Trials Group (NTG)
    • Programs for Assessment of Technology in Health (PATH)
    • The Population Genomics Program (PGP)
    • Population Health Research Institute (PHRI)
    • Health Utilities Group (HUG)
    Clinical Epidemiology

    One research group associated with CE&B that examines Clinical Epidemiology issues is Clinical Advances through Research and Information Translation (CLARITY).

    CLARITY

    CLARITY involves knowledge translation, randomized trials, evidence-based medicine, systematic reviews and associated methodology, quality of life, technology assessment, clinical decision-making, and methods of using and teaching evidence-based medicine.

    CLARITY represents the formal alliance of a group of researchers who have enjoyed a long-standing and fruitful collaboration. Through formal collaboration, CLARITY's clinical advances through research and information translation has been pivotal in creating a renewed sense of spirit, vision and commitment.

    Clinical Epidemiology

    Another research group associated with CE&B that examines Clinical Epidemiology issues is the Centre for Evaluation of Medicines (CEM), a multi-disciplinary resource that provides expertise in clinical pharmacology and toxicology, economics, health policies, behavioral sciences, information technology, research design and biostatistics.

    CEM

    The CEM is a neutral and objective source for information and leading edge analyses in the fields of therapeutics and health policy interventions.

    CEM's areas of proficiency include:

    • pharmaco-economics and health technology assessment
    • pharmaceutical policy evaluation
    • pharmaco-epidemiology and drug use evaluation
    • evidence based therapeutic resource development and implementation
    • health informatics
    Clinical Epidemiology

    An additional research group associated with CE&B that examines Clinical Epidemiology issues is the Neonatal Trials Group (NTG).

    NTG

    The Neonatal Trials Group conducts randomized controlled trials on the aspects of neonatal care in babies. Originally part of the Clinical Trials Methodology Group, NTG was established as a separate entity in 2006 when it joined the Thrombosis and Hemostasis Program and subsequently became part of TAARI with the move to the new research facility at the David Braley Research Institute. NTG’s academic home is in the department of Clinical Epidemiology and Biostatistics in the Faculty of Health Sciences.

    Typically, NTG studies assess the efficacy and safety of common, but insufficiently evaluated, neonatal therapies in very small babies born prematurely who spend their first few months in a neonatal intensive care unit (NICU). The group strives to determine the relative merits of competing care strategies both in terms of medical outcome in the short-term (to initial discharge from the NICU) but, more importantly, in longer term mental and physical outcome.

    Clinical Epidemiology

    Another research group associated with CE&B that examines Clinical Epidemiology issues is Programs for Assessment of Technology in Health.

    PATH

    The Programs for Assessment of Technology in Health (PATH) Research Institute consists of multiple research programs in economic evaluation and health technology assessment (HTA).

    The PATH Research Institute is affiliated with the Centre for Evaluation of Medicines (CEM) at St. Joseph's Healthcare Hamilton and the Department of Clinical Epidemiology and Biostatistics at McMaster University.

    PATH's educational and research activities are separated into 5 primary programs:

    • The Field Evaluation and Economic Assessment Program (FEEAP)
    • The Health Technology Assessment Program (HTAP)
    • The Trial and Economic Modelling Methodology Program (TEMMP)
    • The St. Joseph's Healthcare Hamilton (SJHH) Health Technology Assessment Appraisal & Review Program (SHARP)
    • The Health Technology Assessment Educational Learning Program (HELP)
    Clinical Epidemiology

    Another research group associated with CE&B that examines Clinical Epidemiology issues is the The Population Genomics Program (PGP).

    PGP

    The Population Genomics Program mobilizes McMaster's expertise and resources in population health, genomics, clinical trials and health-research methodology to investigate the influences of gene-gene and gene-environment interactions on disease. It fosters interdisciplinary collaborations among clinical researchers and basic scientists to marshal new insights and discoveries in the burgeoning field of population genomics at McMaster.

    The PGP applies the disciplines of epidemiology, biostatistics and computational biology to reveal and interpret the complex relationships between single nucleotide polymorphisms (SNPS) and other DNA sequence patterns in individuals and the expression of common complex diseases including respiratory disease, autism, obesity, infectious and immunological diseases, type 2 diabetes and cardiovascular diseases in populations.

    Clinical Epidemiology

    An additional research group associated with CE&B that examines Clinical Epidemiology issues is the Population Health Research Institute (PHRI).

    PHRI

    The Population Health Research Institute provides a forum for the conduct of large international clinical trials, population health studies, and studies in outcomes research. While its primary role is to provide leadership in international health research, the PHRI also plays an active role in the education of individual researchers, and in building capacity internationally for the development of global research programs.

    PHRI is an academic health science research institute driven by a passion to improve health outcomes for our global population. Our research is best achieved through worldwide collaboration with governments, academic colleagues, pharmaceutical, and device industries. We believe in an atmosphere that promotes asking questions, questions that lead to new studies and new discoveries, from which our efforts are best rewarded by global solutions.

    Clinical Epidemiology

    One more research group associated with CE&B that examines Clinical Epidemiology issues is the Health Utilities Group (HUG).

    HUG

    The Health Utilities Groupis a multi-disciplinary group of researchers and scientists based in the Department of Clinical Epidemiology and Biostatistics (CE & B) at McMaster University, Hamilton, Canada. HUG develops and applies systems for measuring the health status and health-related quality of life of individuals, clinical groups and general populations. The HUG team meets on a regular basis to plan and manage research projects related to developing and applying tools for measuring health status and health-related quality of life utility scores.

    HUG members developed the Health Utilities Index (HUITM) "family" of classification and preference-based scoring functions during the past 20 years. The HUITM has been included in more than 200 clinical studies, and every major Canadian general population health survey since 1990. The HUI group co-operates internationally with informal groups in France, the U.K., the Netherlands, Austria, Japan, and Singapore.

    Health Economics

    One research group associated with CE&B that examines Health Economics issues is the Centre for Health Economics and Policy Analysis (CHEPA), a world-class interdisciplinary health research centre, and home to the largest concentration of health economists and health policy analysts in Canada.

    CHEPA

    CHEPA researchers bring together a rich set of intellectual resources to tackle complex health and health care problems from a variety of perspectives such as economics, political science, ethics and sociology.

    CHEPA has earned international and national recognition for its significant contributions to research, education and policy, and is known for its work in the fields of knowledge transfer, economic evaluation, health technology assessment, health human resources, and needs-based and primary care funding models.

    Health Economics

    Another research group associated with CE&B that examines Health Economics issues is the Centre for Evaluation of Medicines (CEM), a multi-disciplinary resource that provides expertise in clinical pharmacology and toxicology, economics, health policies, behavioral sciences, information technology, research design and biostatistics.

    CEM

    The CEM is a neutral and objective source for information and leading edge analyses in the fields of therapeutics and health policy interventions.

    CEM's areas of proficiency include:

    • pharmaco-economics and health technology assessment
    • pharmaceutical policy evaluation
    • pharmaco-epidemiology and drug use evaluation
    • evidence based therapeutic resource development and implementation
    • health informatics
    Health Economics

    A third research group associated with CE&B that examines Health Economics issues is Programs for Assessment of Technology in Health (PATH). The PATH Research Institute consists of multiple research programs in economic evaluation and health technology assessment.

    PATH

    PATH's mission is to improve population health by conducting and promoting evidence-based evaluations of the effectiveness and efficiency of new and existing health care technologies.

    The PATH Research Institute is affiliated with the Centre for Evaluation of Medicines (CEM) at St. Joseph's Healthcare Hamilton.

    Health Economics

    A fourth research group associated with CE&B that examines Health Economics issues is the Health Utilities Group (HUG), a multi-disciplinary group of researchers and scientists based in the Department of Clinical Epidemiology and Biostatistics at McMaster University.

    HUG

    HUG develops and applies systems for measuring the health status and health-related quality of life of individuals, clinical groups and general populations. HUG members developed the Health Utilities Index (HUITM) "family" of classification and preference-based scoring functions during the past 20 years. The HUITM has been included in more than 200 clinical studies, and every major Canadian general population health survey since 1990.

    Health Technology Assessment

    Health technology assessment is the interdisciplinary process of systematically reviewing evidence and evaluating efficacy, effectiveness, cost effectiveness and ethical/social impact on patient health and health-care systems of adopting new health-care technologies.

    Within CE&B's Health Research Methodology program, Health Technology Assessment (HTA) is a field of specialization.

    HTA has gained increasing importance in health care decision-making locally and around the world, and over the last decade, there have been numerous important methodological advances in the techniques of HTA. As a result, there is a growing gap between the need for HTA and the availability of skilled researchers to conduct HTAs.

    Population Genomics

    Population genomics is the simultaneous study of numerous genome regions to understand the influences of gene-gene and gene-environment interactions on disease.

    Within CE&B's Health Research Methodology program, the highly-flexible HRM Classic field encourages explorations in Population Genomics.

    Two research groups associated with CE&B examine Population Genomics issues:

    • Population Genomics Program (PGP)
    • Population Health Research Institute (PHRI)
    Population Genomics

    One research group associated with CE&B that examines Population Genomics issues is the the Population Genomics Program (PGP).

    PGP

    The Population Genomics Program mobilizes McMaster's expertise and resources in population health, genomics, clinical trials and health-research methodology to investigate the influences of gene-gene and gene-environment interactions on disease. It fosters interdisciplinary collaborations among clinical researchers and basic scientists to marshal new insights and discoveries in the burgeoning field of population genomics at McMaster.

    The PGP applies the disciplines of epidemiology, biostatistics and computational biology to reveal and interpret the complex relationships between single nucleotide polymorphisms (SNPS) and other DNA sequence patterns in individuals and the expression of common complex diseases including respiratory disease, autism, obesity, infectious and immunological diseases, type 2 diabetes and cardiovascular diseases in populations.

    Health Policy Analysis

    Health policy analysis covers the interdisciplinary investigation of the nature of health policy, how it is made, how it could be made better, and what its impacts are.

    CE&B faculty members are a core part of the McMaster University's Health Policy PhD Program. This interdisciplinary tri-Faculty program, unique in Canada, provides theory and empirical methods for framing, investigating, and answering crucial questions about health policy. Fields of specialization: health economics, political studies, and social organization.

    Five research groups associated with CE&B examine Health Policy Analysis issues:

    • Centre for Health Economics and Policy Analysis (CHEPA)
    • Program in Policy Decision-making (PPD)
    • Centre for Evaluation of Medicines (CEM)
    • Clinical Advances through Research and Information Translation (CLARITY)
    • McMaster Health Forum
    Health Policy Analysis

    One research group associated with CE&B that examines Health Policy Analysis issues is the Centre for Health Economics and Policy Analysis (CHEPA), a world-class interdisciplinary health research centre, and home to the largest concentration of health economists and health policy analysts in Canada.

    CHEPA

    CHEPA researchers bring together a rich set of intellectual resources to tackle complex health and health care problems from a variety of perspectives such as economics, political science, ethics and sociology.

    CHEPA has earned international and national recognition for its significant contributions to research, education and policy, and is known for its work in the fields of knowledge transfer, economic evaluation, health technology assessment, health human resources, and needs-based and primary care funding models.

    Health Policy Analysis

    Another research group associated with CE&B that examines Health Policy Analysis issues is the Program in Policy Decision-making (PPD). The PPD conducts empirical research on how the general climate for efforts to link research to action, research-production processes and systematic efforts to link research to action (including push efforts, efforts to facilitate user pull, user-pull efforts and exchange efforts) foster or hinder the use of research evidence in healthcare management and policymaking

    PPD

    The PPD regularly updates a systematic review of the factors that influence whether and how research evidence is used in public policymaking

    In addition, the PPD derives concrete implications for research funders, research organizations, knowledge brokers, and policy decision-makers about how best to foster the use of research evidence in healthcare management and policymaking .

    Health Policy Analysis

    Another research group associated with CE&B that examines Health Economics issues is the Centre for Evaluation of Medicines (CEM), a multi-disciplinary resource that provides expertise in clinical pharmacology and toxicology, economics, health policies, behavioral sciences, information technology, research design and biostatistics.

    CEM

    The CEM is a neutral and objective source for information and leading edge analyses in the fields of therapeutics and health policy interventions.

    CEM's areas of proficiency include:

    • pharmaco-economics and health technology assessment
    • pharmaceutical policy evaluation
    • pharmaco-epidemiology and drug use evaluation
    • evidence based therapeutic resource development and implementation
    • health informatics
    Health Policy Analysis

    A fourth research group research group associated with CE&B that examines Clinical Epidemiology issues is Clinical Advances through Research and Information Translation (CLARITY).

    CLARITY

    CLARITY involves knowledge translation, randomized trials, evidence-based medicine, systematic reviews and associated methodology, quality of life, technology assessment, clinical decision-making, and methods of using and teaching evidence-based medicine.

    CLARITY represents the formal alliance of a group of researchers who have enjoyed a long-standing and fruitful collaboration. Through formal collaboration, CLARITY's clinical advances through research and information translation has been pivotal in creating a renewed sense of spirit, vision and commitment.

    Health Policy Analysis

    Another research group research group associated with CE&B that examines Health Policy Analysis issues is the McMaster Health Forum .

    McMaster Health Forum

    For concerned citizens and influential thinkers and doers, the McMaster Health Forum strives to be a leading hub for improving health outcomes through collective problem solving.

    Operating at the regional/provincial level and at national levels, the Forum harnesses information, convene stakeholders and prepare action-oriented leaders to meet pressing health issues creatively.

    The Forum acts as an agent of change by empowering stakeholders to set agendas, take well-considered actions and communicate the rationale for actions effectively.

    Health Technology Assessment

    Three research groups associated with CE&B examine Health Technology Assessment issues:

    • Programs for Assessment of Technology in Health (PATH)
    • Clinical Advances through Research and Information Translation (CLARITY)
    • Centre for Health Economics and Policy Analysis (CHEPA)
    Health Technology Assessment

    One research group associated with CE&B that examines Health Technology Assessment issues is Programs for Assessment of Technology in Health (PATH). The PATH Research Institute consists of multiple research programs in economic evaluation and health technology assessment.

    PATH

    PATH's mission is to improve population health by conducting and promoting evidence-based evaluations of the effectiveness and efficiency of new and existing health care technologies.

    The PATH Research Institute is affiliated with the Centre for Evaluation of Medicines (CEM) at St. Joseph's Healthcare Hamilton.

    PATH's educational and research activities are separated into 5 primary programs:

    • The Field Evaluation and Economic Assessment Program (FEEAP)
    • The Health Technology Assessment Program (HTAP)
    • The Trial and Economic Modelling Methodology Program (TEMMP)
    • The St. Joseph's Healthcare Hamilton (SJHH) Health Technology Assessment Appraisal & Review Program (SHARP)
    • The Health Technology Assessment Educational Learning Program (HELP)
    Population Genomics

    An additional research group associated with CE&B that examines Population Genomics issues is the Population Health Research Institute (PHRI).

    PHRI

    The Population Health Research Institute provides a forum for the conduct of large international clinical trials, population health studies, and studies in outcomes research. While its primary role is to provide leadership in international health research, the PHRI also plays an active role in the education of individual researchers, and in building capacity internationally for the development of global research programs.

    PHRI is an academic health science research institute driven by a passion to improve health outcomes for our global population. Our research is best achieved through worldwide collaboration with governments, academic colleagues, pharmaceutical, and device industries. We believe in an atmosphere that promotes asking questions, questions that lead to new studies and new discoveries, from which our efforts are best rewarded by global solutions.

    Health Services Research

    Health services research examines how people get access to health care, how much care costs, and what happens to patients as a result of this care. It focuses on questions about the most effective ways to organize, manage, finance, and deliver high quality clinical and health care, reduce medical errors and improve patient safety.

    Within CE&B's Health Research Methodology program, Health Services Research is a field of specialization. Graduates acquire a broad range of skills—in research synthesis, research design, data analysis and writing for publication—that enable them to conduct rigorous research in areas such as: patterns of care/process of care, small area practice variation studies, appropriateness of care, knowledge translation, economic analysis of health care, service and system organization, patient experience, theoretical underpinnings of health services organization, management, and financing and delivery.

    Knowledge Translation Research

    Knowledge Translation Research focuses on the synthesis, dissemination, exchange, and ethically sound application of knowledge by users towards some goal, e.g. to improve the health of individuals, provide more effective health services and products, and strengthen the health care system.

    Within CE&B's Health Research Methodology program, the highly-flexible HRM Classic field encourages explorations in Knowledge Translation Research.

    Four research groups associated with CE&B examine Health Economics issues:

    • Health Information Research Unit (HIRU)
    • Program in Policy Decision-making (PPD)
    • Programme for Educational Research and Development (PERD)
    • Centre for Health Economics and Policy Analysis (CHEPA)
    Knowledge Translation Research

    The Health Information Research Unit (HIRU) is a research group within CE&B that investigates Knowledge Translation Research issues.

    HIRU

    HIRU conducts research in the field of health information science and is dedicated to the generation of new knowledge about the nature of health and clinical information problems, the development of new information resources to support evidence-based health care, and the evaluation of various innovations in overcoming health care information problems.

    HIRU has earned international and national recognition for its significant contributions to research, education and policy, and is known for its work in the fields of knowledge transfer, economic evaluation, health technology assessment, health human resources, and needs-based and primary care funding models.

    Knowledge Translation Research

    Another research group associated with CE&B that examines Knowledge Translation Research issues is the Program in Policy Decision-making (PPD). The PPD conducts empirical research on how the general climate for efforts to link research to action, research-production processes and systematic efforts to link research to action (including push efforts, efforts to facilitate user pull, user-pull efforts and exchange efforts) foster or hinder the use of research evidence in healthcare management and policymaking

    PPD

    The PPD regularly updates a systematic review of the factors that influence whether and how research evidence is used in public policymaking

    In addition, the PPD derives concrete implications for research funders, research organizations, knowledge brokers, and policy decision-makers about how best to foster the use of research evidence in healthcare management and policymaking .

    Health Informatics

    Health informatics studyies the problems of organization, appraisal, retrieval, and transfer of health information into policy and practice, and developing and testing innovations to improve the translation of evidence into policy and practice.

    There is a new degree program within CE&B that focuses on Health Informatics: the M.Sc. eHealth. Graduates in this vital new interdisciplinary discipline will help transform health services, research and promotion through enabling information technologies and systems.

    Four research groups associated with CE&B explore issues concerning Health Informatics:

    • Health Information Research Unit (HIRU)
    • Clinical Advances through Research and Information Translation (CLARITY)
    • Centre for Evaluation of Medicines (GRADE)
    • Program in Policy Decision-making (PPD)
    Health Technology Assessment

    Another research group associated with CE&B that examines Health Technology Assessment issues is Clinical Advances through Research and Information Translation (CLARITY).

    CLARITY

    CLARITY involves knowledge translation, randomized trials, evidence-based medicine, systematic reviews and associated methodology, quality of life, technology assessment, clinical decision-making, and methods of using and teaching evidence-based medicine.

    CLARITY represents the formal alliance of a group of researchers who have enjoyed a long-standing and fruitful collaboration. Through formal collaboration, CLARITY's clinical advances through research and information translation has been pivotal in creating a renewed sense of spirit, vision and commitment.

    Health Technology Assessment

    The third research group associated with CE&B that examines Health Technology Assessment issues is the Centre for Health Economics and Policy Analysis (CHEPA), a world-class interdisciplinary health research centre, and home to the largest concentration of health economists and health policy analysts in Canada.

    CHEPA

    CHEPA researchers bring together a rich set of intellectual resources to tackle complex health and health care problems from a variety of perspectives such as economics, political science, ethics and sociology.

    CHEPA has earned international and national recognition for its significant contributions to research, education and policy, and is known for its work in the fields of knowledge transfer, economic evaluation, health technology assessment, health human resources, and needs-based and primary care funding models.

    Health Services Research

    Seven research groups associated with CE&B examine Health Services Research issues:

    • Centre for Health Economics and Policy Analysis (CHEPA)
    • Centre for Evaluation of Medicines (CEM)
    • Health Utilities Group (HUG)
    • Supportive Cancer Care Research Unit (SCCRU)
    • System-Linked Research Unit on Health and Social Service Utilization (SLRU)
    • CanChild Centre for Childhood Disability Research(CanChild)
    • Offord Centre for Child Studies
    Health Services Research

    One research group associated with CE&B that examines Health Economics issues is the Centre for Health Economics and Policy Analysis (CHEPA), a world-class interdisciplinary health research centre, and home to the largest concentration of health economists and health policy analysts in Canada.

    CHEPA

    CHEPA researchers bring together a rich set of intellectual resources to tackle complex health and health care problems from a variety of perspectives such as economics, political science, ethics and sociology.

    CHEPA has earned international and national recognition for its significant contributions to research, education and policy, and is known for its work in the fields of knowledge transfer, economic evaluation, health technology assessment, health human resources, and needs-based and primary care funding models.

    Health Services Research

    Another research group associated with CE&B that examines Health Services Research issues is the Centre for Evaluation of Medicines (CEM), a multi-disciplinary resource that provides expertise in clinical pharmacology and toxicology, economics, health policies, behavioral sciences, information technology, research design and biostatistics.

    CEM

    The CEM is a neutral and objective source for information and leading edge analyses in the fields of therapeutics and health policy interventions.

    CEM's areas of proficiency include:

    • pharmaco-economics and health technology assessment
    • pharmaceutical policy evaluation
    • pharmaco-epidemiology and drug use evaluation
    • evidence based therapeutic resource development and implementation
    • health informatics
    Health Services Research

    One more research group associated with CE&B that examines Health Services Research issues is the Health Utilities Group (HUG).

    HUG

    The Health Utilities Groupis a multi-disciplinary group of researchers and scientists based in the Department of Clinical Epidemiology and Biostatistics (CE & B) at McMaster University, Hamilton, Canada. HUG develops and applies systems for measuring the health status and health-related quality of life of individuals, clinical groups and general populations. The HUG team meets on a regular basis to plan and manage research projects related to developing and applying tools for measuring health status and health-related quality of life utility scores.

    HUG members developed the Health Utilities Index (HUITM) "family" of classification and preference-based scoring functions during the past 20 years. The HUITM has been included in more than 200 clinical studies, and every major Canadian general population health survey since 1990. The HUI group co-operates internationally with informal groups in France, the U.K., the Netherlands, Austria, Japan, and Singapore.

    Health Services Research

    Another research group associated with CE&B that examines Health Services Research issues is the Supportive Cancer Care Research Unit (SSCRU).

    SCCRU

    The Supportive Cancer Care Research Unit is committed to the improvement of supportive care services provided to cancer patients and their families through research, and research transfer activities. The ongoing research carried out by the Unit significantly enhances the identification of supportive care needs of cancer patients and facilitates the development, evaluation, and coordination of supportive care services to help meet those needs.

    Health Services Research

    A fifth research group associated with CE&B and concerned with Health Services Research issues is the System-Linked Research Unit on Health and Social Service Utilization (SLRU). SLRU

    The SLRU is a group of university based researchers and community partners dedicated to helping health and social service agencies create new solutions for problems affecting vulnerable children, adults, and seniors.

    The service partners include the regional health and social service departments, social planning councils, home care nursing services, health service and mental health organizations, children’s services, and others.

    Health Services Research

    An additional research group associated with CE&B and concerned with Health Services Research issues is the CanChild Centre for Childhood Disability Research (CanChild). CanChild

    Canchild is a research and educational centre focused on improving the lives of children and youth with disabilities and their families.

    Founded in 1989, CanChild is a world leader in the field of childhood disability. Its cutting-edge research and active strategies for making findings easily accessible to a wide range of audiences make CanChild the premier source for childhood disability information.

    CanChild's multi-disciplinary team includes researchers from pediatrics, rehabilitation medicine (physiatry), occupational therapy, physiotherapy, speech and language pathology, kinesiology, social psychology, epidemiology and biostatistics.

    Health Services Research

    An important research group associated with CE&B and working in Health Services Research is the Offord Centre.

    Offord Centre

    The Offord Centre for Child Studies is researching why some young people are able to overcome enormous obstacles and grow up to be well-adjusted and productive adults whereas others cannot.

    The Centre is also developing, implementing and assessing a number of promising, cost-effective, early interventions to treat and prevent destructive emotional and behavioural problems in our children and youth.

    Knowledge Translation Research

    An additional group associated with CE&B that works on Knowledge Translation Research issues is the Programme for Educational Research and Development (PERD), a component of the Academic Services unit of the Faculty of Health Sciences. PERD houses the educational research and development activity of the Faculty.

    At PERD, educational scholarship and educational programmes are mutually dependent, and the quality of both rests upon careful consideration of the best available evidence. PERD is dedicated to the advancement of research and scholarship in health sciences education, and to the fruitful application of knowledge gained from educational scholarship to the teaching and learning that take place in the Faculty of Health Sciences.

    Knowledge Translation Research

    The fourth research group associated with CE&B and investigating Knowledge Translation Research issues is the Centre for Health Economics and Policy Analysis (CHEPA), a world-class interdisciplinary health research centre, and home to the largest concentration of health economists and health policy analysts in Canada.

    CHEPA

    CHEPA researchers bring together a rich set of intellectual resources to tackle complex health and health care problems from a variety of perspectives such as economics, political science, ethics and sociology.

    CHEPA has earned international and national recognition for its significant contributions to research, education and policy, and is known for its work in the fields of knowledge transfer, economic evaluation, health technology assessment, health human resources, and needs-based and primary care funding models.

    Health Informatics

    The Health Information Research Unit (HIRU) is a research group within CE&B that investigates Health Informatics issues.

    HIRU

    HIRU conducts research in the field of health information science and is dedicated to the generation of new knowledge about the nature of health and clinical information problems, the development of new information resources to support evidence-based health care, and the evaluation of various innovations in overcoming health care information problems.

    HIRU has earned international and national recognition for its significant contributions to research, education and policy, and is known for its work in the fields of knowledge transfer, economic evaluation, health technology assessment, health human resources, and needs-based and primary care funding models.

    Health Informatics

    Another research group research group associated with CE&B that examines Health Informatics issues is Clinical Advances through Research and Information Translation (CLARITY).

    CLARITY

    CLARITY involves knowledge translation, randomized trials, evidence-based medicine, systematic reviews and associated methodology, quality of life, technology assessment, clinical decision-making, and methods of using and teaching evidence-based medicine.

    CLARITY represents the formal alliance of a group of researchers who have enjoyed a long-standing and fruitful collaboration. Through formal collaboration, CLARITY's clinical advances through research and information translation has been pivotal in creating a renewed sense of spirit, vision and commitment.

    Health Informatics

    A third research group research group associated with CE&B that examines Health Informatics issues is the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Working Group. GRADE has developed a common, sensible and transparent approach to grading quality of evidence and strength of recommendations. Many international organizations have provided input into the development of the approach and have started using it.

    GRADE

    Medical evidence, or the recommendations that are based on the evidence, can be of different quality. Sources of evidence range from small laboratory studies or case reports to well-designed large clinical studies that have minimized bias to a great extent. Since poor quality evidence can lead to recommendations that are not in patients’ best interests, it is essential to know whether a recommendation is strong (we can be confident about the recommendation) or weak (we can’t be confident).

    Health Informatics

    Another research group associated with CE&B that examines Health Policy Analysis issues is the Program in Policy Decision-making (PPD). The PPD conducts empirical research on how the general climate for efforts to link research to action, research-production processes and systematic efforts to link research to action (including push efforts, efforts to facilitate user pull, user-pull efforts and exchange efforts) foster or hinder the use of research evidence in healthcare management and policymaking

    PPD

    The PPD regularly updates a systematic review of the factors that influence whether and how research evidence is used in public policymaking

    In addition, the PPD derives concrete implications for research funders, research organizations, knowledge brokers, and policy decision-makers about how best to foster the use of research evidence in healthcare management and policymaking .