Health Research Methods, Evidence, and Impact

Nancy Santesso

PhD (McMaster), MLIS (Western), BASc (Guelph), RD

Assistant Professor, Department of Health Research Methods, Evidence, and Impact

905.525.9140 x 22296

Department of Health Research Methods, Evidence, and Impact
1280 Main St. W.
Hamilton, ON, L8S 4K1


Academic Interests

Dr. Santesso is a registered dietitian by background and obtained her PhD in Health Research Methodology at McMaster University. Her research is in research synthesis methods and guidelines with a focus on communication to patients and the public. She is a member of the GRADE Working Group and works with guideline groups to develop guidelines. She contributes to the Cochrane Collaboration and is an editor with the Cochrane Consumers and Communications Review Group.

Selected Publications

  1. Loudon K, Santesso N, Callaghan M, Thornton J, Harbour J, Graham K, Harbour R, Kunnamo I, Liira H, McFarlane E, Ritchie K, Treweek S. Patient and public attitudes to and awareness of clinical practice guidelines: a systematic review with thematic and narrative syntheses. BMC Health Serv Res. 2014 Jul 27;14:321. doi: 10.1186/1472-6963-14-321.
  2. Santesso N, Rader T, Nilsen ES, Glenton C, Rosenbaum S, Ciapponi A, Moja L, Pardo JP, Zhou Q, Schünemann HJ. A summary to communicate evidence from systematic reviews to the public improved understanding and accessibility of information: a randomized controlled trial. J Clin Epidemiol. 2014 Jul 14. pii: S0895-4356(14)00213-3. doi: 10.1016/j.jclinepi.2014.04.009.
  3. Ryan R, Santesso N, Lowe D, Hill S, Grimshaw J, Prictor M, Kaufman C, Cowie G, Taylor M. Interventions to improve safe and effective medicines use by consumers: an overview of systematic reviews. Cochrane Database Syst Rev. 2014 Apr 29;4:CD007768. doi: 10.1002/14651858.CD007768.pub3.
  4. Santesso N, Carrasco-Labra A, Brignardello-Petersen R. Hip protectors for preventing hip fractures in older people. Cochrane Database Syst Rev. 2014 Mar 31;3:CD001255. doi: 10.1002/14651858.CD001255.pub5.
  5. Schünemann HJ, Wiercioch W, Etxeandia I, Falavigna M, Santesso N, Mustafa R, Ventresca M, Brignardello-Petersen R, Laisaar KT, Kowalski S, Baldeh T, Zhang Y, Raid U, Neumann I, Norris SL, Thornton J, Harbour R, Treweek S, Guyatt G, Alonso-Coello P, Reinap M, Brozek J, Oxman A, Akl EA. Guidelines 2.0: systematic development of a comprehensive checklist for a successful guideline enterprise. CMAJ. 2014 Feb 18;186(3):E123-42. doi: 10.1503/cmaj.131237.
  6. Mustafa RA, Santesso N, Brozek J, Akl EA, Walter SD, Norman G, Kulasegaram M, Christensen R, Guyatt GH, Falck-Ytter Y, Chang S, Murad MH, Vist GE, Lasserson T, Gartlehner G, Shukla V, Sun X, Whittington C, Post PN, Lang E, Thaler K, Kunnamo I, Alenius H, Meerpohl JJ, Alba AC, Nevis IF, Gentles S, Ethier MC,
    Carrasco-Labra A, Khatib R, Nesrallah G, Kroft J, Selk A, Brignardello-Petersen R, Schünemann HJ. The GRADE approach is reproducible in assessing the quality of evidence of quantitative evidence syntheses. J Clin Epidemiol. 2013 Jul;66(7):736-42; quiz 742.e1-5. doi: 10.1016/j.jclinepi.2013.02.004.
  7. Treweek S, Oxman AD, Alderson P, Bossuyt PM, Brandt L, Brożek J, Davoli M, Flottorp S, Harbour R, Hill S, Liberati A, Liira H, Schünemann HJ, Rosenbaum S, Thornton J, Vandvik PO, Alonso-Coello P; DECIDE Consortium. Developing and Evaluating Communication Strategies to Support Informed Decisions and Practice Based on Evidence (DECIDE): protocol and preliminary results. Implement Sci. 2013 Jan 9;8:6. doi: 10.1186/1748-5908-8-6.
  8. Santesso N, Schünemann H, Blumenthal P, De Vuyst H, Gage J, Garcia F, Jeronimo J, Lu R, Luciani S, Quek SC, Awad T, Broutet N; World health Organization Steering Committee for Recommendations on Use of Cryotherapy for Cervical Cancer Prevention. World Health Organization Guidelines: Use of cryotherapy for cervical intraepithelial neoplasia. Int J Gynaecol Obstet. 2012 Aug;118(2):97-102. doi: 10.1016/j.ijgo.2012.01.029.
  9. Guyatt GH, Oxman AD, Santesso N, Helfand M, Vist G, Kunz R, Brozek J, Norris S, Meerpohl J, Djulbegovic B, Alonso-Coello P, Post PN, Busse JW, Glasziou P, Christensen R, Schünemann HJ. GRADE guidelines: 12. Preparing summary of findings tables-binary outcomes. J Clin Epidemiol. 2013 Feb;66(2):158-72. doi:
  10. Santesso N, Akl EA, Bianchi M, Mente A, Mustafa R, Heels-Ansdell D, Schünemann HJ. Effects of higher- versus lower-protein diets on health outcomes: a systematic review and meta-analysis. Eur J Clin Nutr. 2012 Jul;66(7):780-8. doi: 10.1038/ejcn.2012.37.

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