Health Research Methods, Evidence, and Impact

Sohail Mulla

PhD (McMaster)

Assistant Professor (Part-time), Department of Health Research Methods, Evidence, and Impact

Scientific Advisor, CADTH


Office location:
154 University Avenue, Suite 300
Toronto, Ontario, M5H 3Y9


Academic Interests

Dr. Mulla's interests revolve around the development, application, and advancement of research methods to optimally solve important challenges across the life sciences and healthcare sectors. Specific methodological interests include randomized clinical trials, observational studies, systematic reviews, meta-analyses, network meta-analyses, decision modeling, economic evaluations, and surveys.

Selected Publications

  1. Mulla SM, Wang L, Khokhar R, Izhar Z, Agarwal A, Couban R, Buckley DN, Moulin DE, Kallyth SM, Panju A, Turan A, Montori VM, Sessler DI, Thabane L, Guyatt GH, Busse JW. Management of central post-stroke pain: a systematic review of randomized controlled trials. Stroke. 2015;46: 2853-2860.
  2. Mulla SM, Maqbool A, Sivananthan L, Lopes LC, Kamaleldin M, Hsu S, Riva JJ, Vandvik PO, Tsoi L, Ebrahim S, Johnston BC, Olivieri L, Kunz R, Scheidecker A, Buckley DN, Sessler DI, Guyatt GH, Busse JW. Reporting of IMMPACT-recommended core outcome domains among trials assessing opioids for chronic non-cancer pain. Pain. 2015; 156(9):1615-9.
  3. Palmer K, Agoritsas A, Martin D, Scott T, Mulla S, Miller A, Agarwal A, Bresnahan A, Hazzan A, Jeffrey R, Merglen A, Negm A, Siemieniuk R, Bhatnagar N, Dhalla I, Lavis J, You J, Duckett S, Guyatt G. Activity-Based Funding of Hospitals and its Impact on Mortality, Readmission, Discharge Destination, Severity of Illness, and Volume of Care: A Systematic Review and Meta-Analysis. PLoS ONE. 2014;9(10):e109975.
  4. Kasenda B, von Elm E, You J, Blumle A, Tomonaga Y, Saccilotto R, Amstutz A, Bengough T, Meerpohl JJ, Stegert M, Tikkinen KA, Neumann I, Carrasco-Labra A, Faulhaber M, Mulla SM, Mertz D, Akl EA, Bassler D, Busse JW, Ferreira-González I, Lamontagne F, Nordmann A, Gloy V, Raatz H, Moja L, Rosenthal R, Ebrahim S, Schandelmaier S, Xin S, Vandvik PO, Johnston BC, Walter MA, Burnand B, Schwenkglenks M, Hemkens LG, Bucher HC, Guyatt GH, Briel M. Prevalence, characteristics, and publication of discontinued randomized trials. JAMA. 2014;311(10):1045-51
  5. Mulla SM, Scott IA, Jackevicius CA, You JJ, Guyatt GH. Users’ Guides to the Medical Literature: How to Use a Non-inferiority Trial. JAMA. 2012;308(24):2605-11.
  6. Akl EA, Briel M, You JJ, Sun X, Johnston BC, Busse JW, Mulla S, Lamontagne F, Bassler D, Vera C, Alshurafa M, Katsios CM, Zhou Q, Cukirman-Yaffe T, Gangji A, Mills EJ, Walter SD, Cook DJ, Schunemann HJ, Altman DG, Guyatt GH. LOST to follow-up Information in Trials (LOST-IT): Potential impact on estimated treatment effects. BMJ. 2012;344:e2809.
  7. Vandvik PO, Santesso N, Akl EA, You J, Mulla S, Spencer FA, Johnston BC, Brozek J, Kries J, Brandt L, Zhou Q, Schunemann HS, Guyatt G. Formatting modifications in evidence tables improved guideline panellists comprehension and accessibility to information. A randomized trial. J Clin Epidemiol. 2012;65(7):748-55.
  8. MacLean S, Mulla S, Jankowski M, Akl E, Vandvik P, Ebrahim S, McLeod S, Bhatnagar N, Guyatt G. Patient Values and Preferences for Decision Making in Antithrombotic Therapy: A Systematic Review: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141(2 Suppl):e1S-23S.
  9. McDonald SD, Han Z, Mulla S, Beyene J, on behalf of the Knowledge Synthesis Group. Maternal overweight and obesity and the risk of preterm birth and low birth weight: a systematic review and meta-analyses. BMJ. 2010;341:c3428.

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