Clinical Epidemiology & Biostatistics
Alfonso Iorio
MD (Perugia), PhD, FRCP(C)Associate Professor, Department of Clinical Epidemiology and Biostatistics
Joint Member, Department of Medicine
Attending Staff, Hamilton Health Sciences
Associate Editor, Cystic Fybrosis and Genetic Disorders Group, Cochrane Collaboration
Associate Editor, Internal and Emergency Medicine
Steering Committe Member, Italian Registry of Congenital Coagulopathies
905.525.9140 x 22421
905.526.8447
iorioa@mcmaster.ca
McMaster University
1280 Main Street West
CRL-140
Hamilton, Ontario, Canada
L8S 4K1
Office location: CRL-140
Administrative Assistant:
Linda Sheridan
905.525.9140 x 20152
905.526.8447
sheridl@mcmaster.ca
Academic Interests
Current research interests: Knowledge translation research and medical informatics, focused on assessment of impact of knowledge dissemination through information technology and web-based systems. Systematic review metodology, particularly applied to individual patient databases and prognostic questions.
Clinical interests: thrombosis and haemostasis, particularly recurrent VTE and epidemiology of hemophilias.
Current Undergraduate Students
Luxme Mahendira
Anand Jacob
Mengchen Xi
He currently accepts Graduate Students.
Selected Publications
- Iorio A, Marchesini E, Marcucci M, Stobart K, Chan AK. Clotting factor concentrates given to prevent bleeding and bleeding-related complications in people with hemophilia A or B. Cochrane Database Syst Rev. 2011 Sep 7;9:CD003429.
- Douketis J, Tosetto A, Marcucci M, Baglin T, Cosmi B, Cushman M, Kyrle P, Poli D, Tait RC, Iorio A. Risk of recurrence after venous thromboembolism in men and women: patient level meta-analysis. BMJ. 2011 Feb 24;342:d813.
- Iorio A, Kearon C, Filippucci E, Marcucci M, Macura A, Pengo V, Siragusa S, Palareti G. Risk of recurrence after a first episode of symptomatic venous thromboembolism provoked by a transient risk factor: a systematic review. Arch Intern Med. 2010 Oct 25;170(19):1710-6.
- Douketis J, Tosetto A, Marcucci M, Baglin T, Cushman M, Eichinger S, Palareti G, Poli D, Tait RC, Iorio A. Patient-level meta-analysis: effect of measurement timing, threshold, and patient age on ability of D-dimer testing to assess recurrence risk after unprovoked venous thromboembolism. Ann Intern Med. 2010 Oct 19;153(8):523-31
- Iorio A, Matino D, D'Amico R, Makris M. Recombinant Factor VIIa concentrate versus plasma derived concentrates for the treatment of acute bleeding episodes in people with haemophilia and inhibitors. Cochrane Database Syst Rev. 2010 Aug 4;(8):CD004449.
- Iorio A, Halimeh S, Holzhauer S, Goldenberg N, Marchesini E, Marcucci M, Young G, Bidlingmaier C, Brandao LR, Ettingshausen CE, Gringeri A, Kenet G, Knöfler R, Kreuz W, Kurnik K, Manner D, Santagostino E, Mannucci PM, Nowak-Göttl U. Rate of inhibitor development in previously untreated hemophilia A patients treated with plasma-derived or recombinant factor VIII concentrates: a systematic review. J Thromb Haemost. 2010 Jun;8(6):1256-65.
- Iorio A, Marchesini E, Awad T, Gluud LL. Antiviral treatment for chronic hepatitis C in patients with human immunodeficiency virus. Cochrane Database Syst Rev 2010 Jan 20(1):CD004888
- Iorio A, Basileo M, Marcucci M, Guercini F, Camilloni B, Paccamiccio E, Vecchioli M, Iorio AM. No interaction between influenza vaccination and vitamin K antagonist treatment: A placebo controlled, randomized, double-blind, cross-over study. Archives of Internal Medicine, 2010, 170(7);609-16
- A Iorio, W Ageno, B Cosmi, D Imberti, F Lussana, S Siragusa, D Tormene, A Tosetto, M Cattaneo. Guidelines of the Italian Society for Haemostasis and Thrombosis: Objectives and methodology. Thromb Res 2009;124(5):e1-5
- Iorio, E Oliovecchio, M Morfini and PM Mannucci on behalf of the Association of Italian Hemophilia Centres Directors. Italian Registry of Haemophilia and Allied DisorderCurrents. Objectives, methodology and data analysis. Haemophilia 2008, 14: 444–453.