Clinical Epidemiology & Biostatistics
Anne Holbrook
BSc (Toronto), Pharm D(Philadelphia),MD (McMaster), MSc (McMaster), FRCPC, FISPE
Professor, Department of Medicine
Associate Member, Dept of Clinical Epidemiology & Biostatistics
Associate Member, Dept of Pharmaceutical Sciences, University of Toronto
Director, Division of Clinical Pharmacology, Department of Medicine
Senior Scientist, Centre for Evaluation of Medicines, St Joseph's Hospital
Active Medical Staff, McMaster University Medical Centre and St Joseph's Hospital
Fellow, International Society of Pharmacoepidemiology
Chair, Expert Advisory Committee on Pharmacovigilance
Member, Steering Committee, Ontario Program for Optimal Therapy
Member, Canadian Expert Drug Advisory Committee
Member, Drug Quality and Therapeutics Committee (DQTC), MOHLTC
Member, Hamilton Regional Pharmacy and Therapeutics Executive Committee
Associate Editor, ACPJC - Evidence Based Medicine
905.522.1155 x 5269
905.528.7386
holbrook@mcmaster.ca
Centre for Evaluation of Medicines
Level P1
105 Main St. E.
Hamilton, ON
L8N 1G6
Academic Interests
Dr. Holbrook's professional life is a unique combination of direct patient care, educational leadership, and applied research—all focused on evidence-based therapeutics.
Current HRM Graduate Students
Kathy Li (MSc)
Gihan Perera (MSc)
Wojciech Wiercioch (MSc)
Janine Arkinson (MSc)
Ivan Scherbatykh (PhD)
Dr. Holbrook also supervises students at the University of Toronto
Selected Publications
- Holbrook A, Keshavjee K, Sebaldt R, Grootendorst P, Levine M, Goldsmith C, Willison D, Brogan T, Peterson R, Tennant. Evaluation of data sources to support pharmacosurveillance. Final report of the Health Policy Research Program, Health Canada. January 2005. 84p.
- Holbrook A, Grootendorst P, Willison D, Goldsmith C, Sebaldt, Keshavjee K. Can current electronic systems meet drug safety and effectiveness requirements? AMIA Symposium Proceedings 2005:335-339.
- Holbrook AM, Pereira JA, Labiris R, McDonald H, Douketis JD, Crowther M, Wells, PS. Systematic Overview Of Warfarin And Its Drug And Food Interactions. Archives of Internal Medicine 2005;165:1095-1106.
- Holbrook A. Treating insomnia. BMJ 2004;329:1198-99.
- Holbrook A, Goldsmith C. Innovation and placebos in research: a new design of clinical trial. Lancet 2003:362;2036-37.
- Grootendorst P, Marshall J, Holbrook A, Dolovich L, O’Brien B, Levy A. The impact of differential cost sharing of non-steroidal anti-inflammatory agents on the use and costs of analgesic drugs. Health Services Research 2005;40:1297-1317.
- Pereira JA, Holbrook AM, Dolovich L, Goldsmith C, Thabane L, Douketis JD, Crowther M, Bates SM, Ginsberg JS,. Are brand-name and generic warfarin interchangeable? Results from multiple n-of-1 randomized crossover trials. Annals of Pharmacotherapy 2005;39:1188-1193.