Health Research Methods, Evidence, and Impact

Gordon Guyatt

BSc (Toronto), MD (McMaster), MSc (McMaster) FRCPC, OC

Distinguished Professor, Department of Health Research Methods, Evidence, and Impact

Joint Member, Department of Medicine

Member, CLARITY (Clinical Advances through Research and Information Translation)

905.525.9140 x22900

McMaster University
1280 Main Street West, Rm. 2C12
Hamilton, Ontario, Canada
L8S 4K1

Office location: HSC-2C12

Administrative Support: Deborah Maddock
CLARITY Office Manager
905.525.9140 x 22900

Academic Interests

Dr. Guyatt's areas of interest include: the dissemination of concepts of evidence-based medicine to health workers and health-care consumers; the methodology of clinical practice guidelines and medical decision-making; systematic review methodology; and ascertaining patients' values and preferences. Dr. Guyatt has been a leading exponent of evidence-based approaches to clinical practice, having coined the term "evidence-based medicine" in 1990.

Selected Publications

  1. Guyatt GH, Oxman AD, Schünemann HJ, Tugwell P, Knottnerus A. GRADE guidelines: A new series of articles in the Journal of Clinical Epidemiology. J Clin Epidemiol. 2011 Apr:64(4):380-2.
  2. Guyatt G, Akl EA, Hirsh J, Kearon C, Crowther M, Gutterman D, Lewis SZ, Nathanson I, Jaeschke R, Schünemann H. The vexing problem of guidelines and conflict of interest: a potential solution. Ann Intern Med. 2010 Jun 1;152(11):738-41.
  3. Johnston BC, Thorlund K, Schünemann HJ, Xie F, Murad MH, Montori VM, Guyatt GH. Improving he interpretation of quality of life evidence in meta-analysis: the application of minimal important difference units. Health Qual Life Outcomes. 2010 Oct 11;8:116.
  4. Sun X, Briel M, Walter SD, Guyatt GH. Is a subgroup effect believable? Updating criteria to evaluate the credibility of subgroup analyses. BMJ. 2010 Mar 30;340;c117.
  5. Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, Schünemann HJ, for the GRADE Working Group. GRADE: an emerging concensus on rating quality of evidence and strength of recommendations. BMJ 2008 Apr 26;336(7650):924-926.
  6. Guyatt GH, Mills EJ. In the era of systematic reviews, does the size of an individual trial still matter. PLoS Med. 2008 Jan 3;5(1):e4.
  7. Ferreira-Gonzalez I, Busse JW, Heels-Ansdell D, Montori VM, Akl EA, Bryant DM, Alonso-Coello P, Alonso J, Worster A, Upadhye S, Jaeschke R, Schünemann HJ, Permanyer-Miralda G, Pacheco-Huergo V, Domingo-Salvany A, Wu P, Mills EJ, Guyatt GH. Problems with use of composite end points in cardiovascular trials: systematic review of randomised controlled trials. BMJ 2007 Apr 14;334(7597):786.
  8. Guyatt G, Schünemann H. How can quality of life researchers make their work more useful to health workers and their patients?. Qual Life Res. 2007 Sep;16(7):1097-105.

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