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Clinical Epidemiology & Biostatistics

Lauren Griffith

Academic Interests

Research interests include statistical and methodolic issues related to observational study meta-analysis. Involved in an individual participant data meta-analysis of workplace exposures and low back pain.

Selected Publications

1. Griffit LE, Wells RP, Shannon HS, Walter SD, Cole DC, Hogg-Johnson S for the Meta-Analysis of Pain in the Lower Back and Work Exposures (MAPLE) Collaborative Group.  Developing common metrics of mechanical exposures across etiologic studies of low back pain in working populations for use in meta-analysis.  Occup Environ Med 2008;65:467-481.
2. Griffith LE, Hogg-Johnson S, Cole DC, Krause N, Hayden J, Burdorf A, Leclerc A, Coggon D, Bongers P, Walter SD, Shannon HS for the Meta-Analysis of Pain in the Lower Back and Work Exposures (MAPLE) Collaborative Group.  Low-back pain definitions in occupational studies were categorized for a meta-analysis using Delphi consensus methods.  J Clin Epidemiol 2007;60:625-633.
3. Schünemann HJ, Goldstein R, Mador MJ, McKim D, Stahl E, Puhan M, Griffith LE, Grant B, Austin P, Collins R, Guyatt GH. A randomised trial to evaluate the self-administered standardised chronic respiratory questionnaire. Eur Respir J 2005;25:31-40.
4. Crowther M, Cook DJ, Griffith LE, Meade M, Hanna S, Rabbat C, Bates SM, Geerts W, Johnston M, Guyatt GH. Neither baseline tests of molecular hypercoagulability nor D-dimer levels predict deep venous thrombosis in critically ill medical-surgical patients. Intens Care Med 2005;31:48-55.
5. Hill SA, Devereaux PJ, Griffith L , Opie J, McQueen MJ, Panju A, Stanton E, Guyatt GH. Can troponin I measurement predict short-term serious cardiac outcomes in patients presenting to the emergency department with possible acute coronary syndrome? Can J Emerg Med 2004; 6:22 -30.
6. Cook D, Meade M, Guyatt G, Griffith L, Granton J, Geerts W, Crowther M, the Canadian Critical Care Trials Group. Clinically important deep vein thrombosis in the intensive care unit: a survey of intensivists. Crit Care 2004;8:R145-R152.
7. Griffith L , Cook D, Hanna S, Rocker G, Sjokvist P, Dodek P, Marshall J, Levy M, Varon J, Finfer S, Jaeschke R, Buckingham L, Guyatt G. Clinician discomfort with life support plans for mechanically ventilated patients. Intens Care Med 2004;30:1783-1790.
8. Sinuff T, Cook DJ, Rocker GM, Griffith LE, Walter SD, Fisher MM, Dodek PM, Sjokvist P, McDonald E, Marshall JC, Kraus PA, Levy MM, Lazar NM, Guyatt GH, for the Level of Care Study Investigators & the Canadian Critical Care Trials Group. Can J Anesth 2004;51:10:1034-1041.
9. Meade MO , Jacka MJ, Cook DJ, Dodek P, Griffith L , Guyatt GH for the Canadian Critical Care Trials Group. Survey of interventions for the prevention and treatment of acute respiratory distress syndrome. Crit Care Med 2004;32:946-954.
10. Schünemann HJ, Griffith L, Jaeschke R, Goldstein R, Stubbing D, Guyatt GH. Evaluation of the minimal important difference for the feeling thermometer and the St. George’s Respiratory Questionnaire in patients with chronic airflow obstruction. J Clin Epidemiol 2003;56:1170-1176.

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