Clinical Epidemiology & Biostatistics


PJ Devereaux

MD (Dalhousie), PhD (McMaster) FRCPC

Associate Professor, Department of Clinical Epidemiology and Biostatistics

Joint Member, Department of Medicine (Cardiology)

Member, CLARITY (Clinical Advances Through Research and Information Translation)

Member, Population Health Research Institute

Heart and Stroke Foundation of Ontario Career Investigator Award to pursue research in major vascular complications after non-cardiac surgery

Attending Staff, Hamilton Health Sciences, Cardiac Care Unit

905.527.4322 x 40654
905.297.3778
philipj@mcmaster.ca

McMaster University
Faculty of Health Sciences
1280 Main Street West, Rm. 2C12
Hamilton, Ontario, Canada
L8S 4K1

Office location: HSC-2C12

Administrative Coordinator: Heather Gill
905.527.4322 x40654
905.297.3778
hgill@mcmaster.ca

 

Academic Interests

Dr. Devereaux obtained his MD from McMaster University.  After medical school he completed a residency in internal medicine at the University of Calgary and a residency in cardiology at Dalhousie University.  He then completed a PhD in Clinical Epidemiology at McMaster University.  Dr. Devereaux holds a Heart and Stroke Foundation of Ontario Career Investigator Award.   He was the Co-PI of the POISE-1 Trial, the world’s largest cardiac randomized controlled trial in patients undergoing noncardiac surgery.  Dr. Devereaux is the PI of the VISION Study that evaluated major vascular complications in a representative sample of 40,000 patients undergoing noncardiac surgery in 14 centres in 10 countries.  He is also the PI of the POISE-2 Trial that evaluated the effects of clonidine versus placebo and ASA versus placebo in a factorial 10,000 patient trial among patients undergoing noncardiac surgery.  Dr. Devereaux has published over 180 peer reviewed papers and 40 editorials, book chapters and commentaries.  He is currently the Head of Cardiology and the Perioperative Medicine Program at the Juravinski Hospital and Cancer Centre.  He is also the Scientific Leader of the Perioperative Medicine and Surgical Research Group at the Population Health Research Institute. 

Selected Publications

  1. Devereaux PJ, Xavier D, Pogue J, Guyatt G, Sigamani A, Garutti I, Leslie K, Rao-Melacini P, Chrolavicius S, Yang H, MacDonald C, Avezum A, Lanthier L, Hu W, Yusuf S, on behalf of the POISE (PeriOperative ISchemic Evaluation) Investigators. Characteristics and short-term prognosis of perioperative myocardial infarction in patients undergoing noncardiac surgery. Ann Intern Med. 2011; 154: 523-528.
  2. Devereaux PJ, Chan MTV, Eisenach J, Schricker T, Sessler DI. The need for large clinical studies in perioperative medicine. Anesthesiology. 2012; 116: 1169-1175.  
  3. Lamy A, Devereaux PJ, Prabhakaran D, Taggart DP, Hu A, Paolasso E, Straka Z, Piegas LS, Akar AR, Jain AR, Noiseux N, Padmanabhan C, Bahamondes JC, Novick RJ, Vaijyanath P, Reddy SK, Tao L, Olavegogeascoechea PA, Airan B, Sulling TA, Whitlock RP, Ou Y, Ng J, Chrolavicius S, Yusuf S, on behalf of the CORONARY Investigators.  Off-pump or on-pump coronary artery bypass grafting at 30 days. N Engl J Med. 2012; 366: 1489-1497. 
  4. Devereaux PJ, Chan MTV, Alonso-Coello P, Walsh M, Berwanger O, Villar JC, Wang CY, Garutti RI, Jacka MJ, Sigamani A, Srinathan S, Biccard BM, Chow CK, Abraham V, Tiboni M, Pettit S, Szczeklik W, Buse GL, Botto F, Guyatt G, Heels-Ansdell D, Sessler DI, Thorlund K, Garg AX, Mrkobrada M, Thomas S, Rodseth RN, Pearse RM, Thabane L, McQueen MJ, VanHelder T, Bhandari M, Bosch J, Kurz A, Polanczyk CA, Malaga G, Nagele P, Le Manach Y, Leuwer M, Yusuf S, and the VISION Investigators. Association between postoperative troponin levels and 30-day mortality among patients undergoing noncardiac surgery.  JAMA. 2012; 307: 2295-2304.    
  5. Lamy A, Devereaux PJ, Prabhakaran D, Taggart DP, Hu S, Paolasso E, Straka Z, Piegas LS, Akar AR, Jain AR, Noiseux N, Padmanabhan C, Bahamondes JC, Novick RJ, Vaijyanath P, Reddy SK, Tao L, Olavegogeascoechea PA, Airan B, Sulling TA, Whitlock RP, Ou Y, Ng J, Pogue J, Chrolavicius S, Yusuf S, for the CORONARY Investigators.  Effects of off-pump and on-pump coronary-artery bypass grafting at 1 year. N Engl J Med. 2013; 368:1179-1188.  
  6. Walsh M, Srinathan SK, McAuley DF, Mrkobrada M, Levine O, Ribic C, Molnar AO, Dattani ND, Burke A, Guyatt G, Thabane L, Walter SD, Pogue J, Devereaux PJ. The statistical significance of randomized controlled trial results is frequently fragile: A case for a fragility index.  J Clin Epidemiol. 2014; 67: 622-628.  
  7. Botto F, Alonso-Coello P, Chan MTV, Villar JC, Xavier D, Srinathan S, Guyatt G, Cruz P, Graham M, Wang CY, Berwanger O, Pearse RM, Biccard BM, Abraham V, Malaga G, Hillis GS, Rodseth RN, Cook D, Polanczyk CA, Szczeklik W, Sessler DI, Sheth T, Ackland GL, Leuwer M, Garg AX, LeManach Y, Pettit S, Heels-Ansdell D, Lurati Buse G, Walsh M, Sapsford R, Schünemann HJ, Kurtz A, Thomas S, Mrkobrada M, Thabane L, Gerstein H, Paniagua P, Nagele P, Raina P, Yusuf S, Devereaux PJ, and the VISION Investigators.  Myocardial Injury after Noncardiac Surgery:  A large, international, prospective cohort study establishing diagnostic criteria, characteristics, predictors, and 30-day outcomes. Anesthesiology 2014; 120:564-578. (Published Online First).     
  8. Devereaux PJ, Sessler DI, Leslie K, Kurz A, Mrkobrada M, Alonso-Coello P, Villar JC, Sigamani A, Biccard BM, Meyhoff CS, Parlow JL, Guyatt G, Robinson A, Garg AX, Rodseth RN, Botto F, Lurati Buse G, Xavier D, Chan MTV, Tiboni M, Cook D, Kumar PA, Forget P, Malaga G, Fleischmann E, Amir M, Eikelboom J, Mizera R, Torres D, Wang CY, VanHelder T, Paniagua P, Berwanger O, Srinathan S, Graham M, Pasin L, Le Manach Y, Gao P, Pogue J, Whitlock R, Lamy A, Kearon C, Chow C, Pettit S, Chrolavicius S, Yusuf S, on behalf of the POISE-2 Investigators.  Clonidine in patients undergoing noncardiac surgery.  N Engl J Med. 2014: 370: 1504-1503. (Published Online First).        
  9. Devereaux PJ, Mrkobrada M, Sessler DI, Leslie K, Alonso-Coello P, Kurz A, Villar JC, Sigamani A, Biccard BM, Meyhoff CS, Parlow JL, Guyatt G, Robinson A, Garg AX, Rodseth RN, Botto F, Lurati Buse G, Xavier D, Chan MTV, Tiboni M, Cook D, Kumar PA, Forget P, Malaga G, Fleischmann E, Amir M, Eikelboom J, Mizera R, Torres D, Wang CY, VanHelder T, Paniagua P, Berwanger O, Srinathan S, Graham M, Pasin L, Le Manach Y, Gao P, Pogue J, Whitlock R, Lamy A, Kearon C, Baigent C, Chow C, Pettit S, Chrolavicius S, Yusuf S, on behalf of the POISE-2 Investigators.  Aspirin in patients undergoing noncardiac surgery.  N Engl J Med. 2014: 370: 1494-1503. (Published Online First).      
  10. Garg AX, Devereaux PJ, Yusuf S, Cuerden MS, Parikh CR, Coca SG, Walsh M, Novick R,  Cook RJ, Jain AR, Pan X, Noiseux N, Vik K, Stolf NA, Ritchie A, Favaloro RR, Parvathaneni S, Whitlock RP, Ou Y, Lawrence M, Lamy A, for the CORONARY Investigators.  Kidney function after off-pump or on-pump coronary artery bypass graft surgery: A randomized clinical trial.  JAMA.  2014; 311: 2191-2198. (Published Online First).    

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