Health Research Methods, Evidence, and Impact

Deborah J. Cook

MSc(McMaster), Critical Care Medicine (Stanford),

Canada Research Chair of Research Transfer in Intensive Care

Professor, Department of Medicine, Health Research Methods, Evidence, and Impact

Joint Member, Dept of Health Research Methods, Evidence, and Impact

Academic Chair, Critical Care Medicine, McMaster University

Co-Chair, Critical Research Interest Group

Member, CLARITY (Clinical Advances through Research and Information Translation)

Royal Society of Canada (2009)

ACCM Distinguished Investigator Award (2006)

OCUFA Distinguished Teacher Award (2006)

Canadian Society of Internal Medicine Dr. David Sackett Senior Investigator Award (2006)

905.525.9140 x 22900

McMaster University
Faculty of Health Sciences
1280 Main Street West, Rm. 2C11
Hamilton, Ontario, Canada
L8S 4K1

Office location: HSC-2C11

Administrative Assistant: Laurel Grainger
905.525.9140 x 23162

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Academic Interests

Dr. Cook designs and conducts patient-centered research in the ICU. She is interested in risk factors for serious illness, prevention of ICU-acquired complications, life support technology, and end-of-life decisions for critically ill patients. Her educational interests are in evidence based practice and research uptake. Her methodological interests are in the design and conduct of multicenter randomized trials, minimizing bias in systematic reviews, and incorporation of diverse kinds of evidence into practice guidelines and clinical recommendations.

Selected Publications

  1. Cook DJ, Rocker G, Marshall J et al for the Level of Care Study Investigators and The Canadian Critical Care Trials Group. Withdrawal of mechanical ventilation in anticipation of death in the intensive care unit. N Engl J Med 2003;349:1123-32.
  2. Cook D, Meade M, Guyatt G, Walter S, Heels-Ansdell D, Warkentin TE, Zytaruk N, Crowther M, Geerts W, Cooper DJ, Vallance S, Qushmaq I, Rocha M, Berwanger O, Vlahakis NE, Writing Committee, for the PROTECT Investigators, & the Canadian Critical Care Trials Group & the Australian and New Zealand Intensive Care Society Clinical Trials Group.  A randomized trial of dalteparin versus unfractionated heparin in critically Ill patients.  N Engl J Med 2011;epub ahead of print (10.1056/NEJMoa1014475).
  3. Cook DJ, Guyatt GH, Rocker G et al for the Canadian Critical Care Trials Group. Cardiopulmonary resuscitation directives on admission to the Intensive Care Unit: an international observational study. Lancet 2001;358:1941-5.
  4. Cook DJ, Walter S, Cook RJ, et al for the Canadian Critical Care Trials Group. The incidence and risk factors for ventilator-associated pneumonia in critically ill patients. Ann Intern Med 1999;129(6):433-40.
  5. Cook DJ, Guyatt GH, Marshall J, et al for the Canadian Critical Care Trials Group. A comparison of sucralfate and ranitidine for prevention of upper gastrointestinal bleeding in patients requiring mechanical ventilation. N Engl J Med 1999;338(12):791-7.
  6. Cook DJ, Fuller H, Guyatt GH, et al for the Canadian Critical Care Trials Group. Risk factors for gastrointestinal bleeding in critically ill patients. N Engl J Med 1994;330:377-81

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