Biochemistry and Biomedical Sciences
Director, Michael G. DeGroote Institute for Infectious Disease Research
Canada Research Chair in Antimicrobial Biochemistry
905-525-9140 ext. 22664
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- Microbiological Biochemistry
- Antimicrobial Research
The discovery of antibiotic compounds derived from microorganisms some 50 years ago has provided an arsenal of drugs for the treatment of infectious diseases.
Unfortunately, many pathogenic organisms have acquired resistance to antibiotics and now some infections are virtually untreatable by standard antibiotic therapies. In order to address this problem we are using three complementary strategies. The first is direct study of the molecular mechanisms of bacterial antibiotic resistance, the second is the elucidation of antibiotic biosynthesis with the ultimate goal of manipulating the biosynthetic pathway to produce novel antibiotics.